Nigel Klein

What is he best known for?

The fields of study he is best known for:

• Internal medicine
• Immune system
• Gene

His primary scientific interests are in Immunology, Internal medicine, Mannan-binding lectin, Microbiology and Inflammation. His Immunology study frequently draws connections to adjacent fields such as Intensive care. The concepts of his Internal medicine study are interwoven with issues in Gastroenterology and Endocrinology.

His biological study spans a wide range of topics, including Prospective cohort study, Complement system and Collectin. His research integrates issues of Neisseria meningitidis, Lipopolysaccharide, Microbiome and Intestinal mucosa in his study of Microbiology. While the research belongs to areas of Inflammation, he spends his time largely on the problem of Aspirin, intersecting his research to questions surrounding Macrophage activation syndrome, Etiology, Bradykinin, Heart disease and Kawasaki disease.

His most cited work include:

• Oligosaccharides in Human Milk: Structural, Functional, and Metabolic Aspects (828 citations)
• Mental Stress Induces Transient Endothelial Dysfunction in Humans (517 citations)
• Mannose-Binding Lectin Binds to a Range of Clinically Relevant Microorganisms and Promotes Complement Deposition (494 citations)

What are the main themes of his work throughout his whole career to date?

Nigel Klein mainly focuses on Immunology, Internal medicine, Microbiology, Pediatrics and Immune system. His Mannan-binding lectin, Inflammation, Sepsis, T cell and Cytokine study are his primary interests in Immunology. His Mannan-binding lectin research is multidisciplinary, incorporating elements of Complement system, Collectin and Genotype.

His Internal medicine study integrates concerns from other disciplines, such as Gastroenterology, Endocrinology and Pathology. The Microbiology study combines topics in areas such as Neisseria meningitidis and Lipopolysaccharide. His Endothelium research includes elements of Cell adhesion molecule and Cell biology.

He most often published in these fields:

• Immunology (43.98%)
• Internal medicine (21.17%)
• Microbiology (11.50%)

What were the highlights of his more recent work (between 2017-2021)?

• Immunology (43.98%)
• Internal medicine (21.17%)
• Randomized controlled trial (4.38%)

In recent papers he was focusing on the following fields of study:

Nigel Klein spends much of his time researching Immunology, Internal medicine, Randomized controlled trial, Viral load and Antiretroviral therapy. As part of his studies on Immunology, Nigel Klein often connects relevant subjects like Endothelial dysfunction. His Internal medicine research incorporates themes from Gastroenterology and Infection control.

Nigel Klein usually deals with Randomized controlled trial and limits it to topics linked to Adverse effect and Young adult. His Viral load research is multidisciplinary, incorporating perspectives in Cross-sectional study and Reverse-transcriptase inhibitor. His research in Antiretroviral therapy intersects with topics in Hiv infected and Immunophenotyping.

Between 2017 and 2021, his most popular works were:

• Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans (77 citations)
• Paediatric European Network for Treatment of AIDS (PENTA) guidelines for treatment of paediatric HIV‐1 infection 2015: optimizing health in preparation for adult life (58 citations)
• Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells (48 citations)

In his most recent research, the most cited papers focused on:

• Internal medicine
• Gene
• Immune system

His scientific interests lie mostly in Immunology, Internal medicine, Randomized controlled trial, Viral load and Pregnancy. Nigel Klein interconnects Penetrance and Hematopoietic stem cell transplantation in the investigation of issues within Immunology. His work on Cystic fibrosis as part of general Internal medicine research is frequently linked to Nontuberculous mycobacteria, thereby connecting diverse disciplines of science.

As part of the same scientific family, he usually focuses on Viral load, concentrating on Antiretroviral therapy and intersecting with Discontinuation, Rate ratio and Hiv infected. His Pregnancy study combines topics from a wide range of disciplines, such as Mycoplasma, DNA extraction, Physiology and Obstetrics. His Immune system study combines topics in areas such as Cord Blood Stem Cell Transplantation and Transplantation.