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Petter Brandtzaeg

Petter Brandtzaeg

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Microbiology
Norway
2026

D-Index & Metrics

Microbiology

D-Index
67
Citations
14686
World Ranking
2285
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Microbiology in Norway Leader Award
  • 2025 - Research.com Microbiology in Norway Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Immune system
  • Internal medicine
  • Antibody

His scientific interests lie mostly in Immunology, Meningococcal disease, Pathology, Antibody and Meningitis. His Immunology research incorporates elements of Macrophage, Molecular biology and Intestinal mucosa. The subject of his Meningococcal disease research is within the realm of Neisseria meningitidis.

The concepts of his Neisseria meningitidis study are interwoven with issues in Transmission and Carriage. His studies deal with areas such as Bacteremia, Interleukin 6, Cerebrospinal fluid and Virology as well as Meningitis. While the research belongs to areas of Septic shock, Petter Brandtzaeg spends his time largely on the problem of Shock, intersecting his research to questions surrounding Andrology.

His most cited work include:

  • Epidemic meningitis, meningococcaemia, and Neisseria meningitidis. (709 citations)
  • Plasma Endotoxin as a Predictor of Multiple Organ Failure and Death in Systemic Meningococcal Disease (500 citations)
  • Update on Meningococcal Disease with Emphasis on Pathogenesis and Clinical Management (488 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Immunology, Neisseria meningitidis, Microbiology, Septic shock and Meningococcal disease. His research on Immunology frequently connects to adjacent areas such as Intestinal mucosa. His research integrates issues of Meningitis, Whole blood, Complement system, Wild type and Fulminant in his study of Neisseria meningitidis.

His study on Microbiology also encompasses disciplines like

  • Lipopolysaccharide together with Macrophage inflammatory protein,
  • Molecular biology most often made with reference to Monocyte. His work in Septic shock covers topics such as Tumor necrosis factor alpha which are related to areas like Interleukin. In his study, Antibiotics is inextricably linked to Internal medicine, which falls within the broad field of Meningococcal disease.

He most often published in these fields:

  • Immunology (57.96%)
  • Neisseria meningitidis (41.40%)
  • Microbiology (39.49%)

What were the highlights of his more recent work (between 2012-2021)?

  • Neisseria meningitidis (41.40%)
  • Septic shock (25.48%)
  • Immunology (57.96%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Neisseria meningitidis, Septic shock, Immunology, Microbiology and Whole blood. Petter Brandtzaeg has included themes like Lipopolysaccharide, Internal medicine, Case fatality rate and Complement system in his Neisseria meningitidis study. Petter Brandtzaeg combines subjects such as Meningitis, Tumor necrosis factor alpha, Spleen, Meningococcal disease and Fulminant with his study of Septic shock.

Petter Brandtzaeg interconnects Limulus amebocyte lysate, Invasive disease, Pathogenesis, Severe sepsis and Disseminated intravascular coagulation in the investigation of issues within Meningococcal disease. Immunology and Gene expression are frequently intertwined in his study. His Whole blood research includes elements of Wild type, Mutant, Meningococcal sepsis and Tissue factor.

Between 2012 and 2021, his most popular works were:

  • Microparticle-associated tissue factor activity correlates with plasma levels of bacterial lipopolysaccharides in meningococcal septic shock (33 citations)
  • Microparticle-associated tissue factor activity correlates with plasma levels of bacterial lipopolysaccharides in meningococcal septic shock (33 citations)
  • Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood. (18 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Internal medicine
  • Antibody

Petter Brandtzaeg focuses on Tissue factor, Immunology, Neisseria meningitidis, Whole blood and Septic shock. His Tissue factor research is multidisciplinary, relying on both Gene expression profiling, Receptor, Signal transduction, Regulation of gene expression and Interleukin 10. His research in Immunology is mostly focused on Cytokine.

Neisseria meningitidis is closely attributed to Lipopolysaccharide in his study. His research in Lipopolysaccharide intersects with topics in Tumor necrosis factor alpha, Inflammation, Shock, Fulminant and Sudden infant death syndrome. His Whole blood study incorporates themes from Meningitis, Limulus amebocyte lysate, Meningococcal disease, Disseminated intravascular coagulation and Thrombin.

Best Publications

  • The complex pattern of cytokines in serum from patients with meningococcal septic shock. Association between interleukin 6, interleukin 1, and fatal outcome.

    A Waage;P Brandtzaeg;A Halstensen;P Kierulf

  • Epidemic meningitis, meningococcaemia, and Neisseria meningitidis.

    David S Stephens;David S Stephens;Brian Greenwood;Petter Brandtzaeg

  • Update on Meningococcal Disease with Emphasis on Pathogenesis and Clinical Management

    M. van Deuren;P. Brandtzaeg;J.W.M. van der Meer

  • Plasma Endotoxin as a Predictor of Multiple Organ Failure and Death in Systemic Meningococcal Disease

    Petter Brandtzaeg;Peter Kierulf;Peter Gaustad;Andreas Skulberg

  • Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma.

    E. M. Nilsen;K. E. A. Lundin;P. Krajci;H. Scott

  • Increased macrophage subset in inflammatory bowel disease: apparent recruitment from peripheral blood monocytes.

    J Rugtveit;P Brandtzaeg;T S Halstensen;O Fausa

  • Net inflammatory capacity of human septic shock plasma evaluated by a monocyte-based target cell assay: identification of interleukin-10 as a major functional deactivator of human monocytes

    P Brandtzaeg;L Osnes;R Ovstebø;G B Joø

  • Regulation of the formation and external transport of secretory immunoglobulins.

    I N Norderhaug;F E Johansen;H Schjerven;P Brandtzaeg

  • Complement activation and endotoxin levels in systemic meningococcal disease.

    Petter Brandtzaeg;Tom Eirik Mollnes;Peter Kierulf

  • The quantitative association of plasma endotoxin, antithrombin, protein C, extrinsic pathway inhibitor and fibrinopeptide A in systemic meningococcal disease.

    Petter Brandtzaeg;Per Morten Sandset;Gun Britt Joø;Reidun Øvstebø

  • Plasminogen activator inhibitor 1 and 2, alpha-2-antiplasmin, plasminogen, and endotoxin levels in systemic meningococcal disease.

    Petter Brandtzaeg;Gun Britt Joø;Berit Brusletto;Peter Kierulf

  • Cytokine profiles of cultured microvascular endothelial cells from the human intestine.

    E. M. Nilsen;F.-E. Johansen;F. L. Jahnsen;K. E. A. Lundin

  • The clinical condition of IgA-deficient patients is related to the proportion of IgD- and IgM-producing cells in their nasal mucosa.

    P Brandtzaeg;G Karlsson;G Hansson;B Petruson

  • B cell attracting chemokine 1 (CXCL13) and its receptor CXCR5 are expressed in normal and aberrant gut associated lymphoid tissue.

    Carlsen Hs;Baekkevold Es;Johansen Fe;Haraldsen G

  • Differential distribution of B7.1 (CD80) and B7.2 (CD86) costimulatory molecules on mucosal macrophage subsets in human inflammatory bowel disease (IBD)

    J. Rugtveit;A. Bakka;P. Brandtzaeg

  • Expression and Regulation of Adhesion Molecules ICAM‐1 (CD54) and LFA‐3 (CD58) in Human Intestinal Epithelial Cell Lines

    D. Kvale;P. Krajci;P. Brandtzaeg

  • Meningococcal endotoxin in lethal septic shock plasma studied by gas chromatography, mass-spectrometry, ultracentrifugation, and electron microscopy.

    P Brandtzaeg;K Bryn;P Kierulf;R Ovstebø

  • Microbial colonization influences composition and T-cell receptor V beta repertoire of intraepithelial lymphocytes in rat intestine.

    L. Helgeland;J. T. Vaage;B. Rolstad;T. Midtvedt

  • Distribution of macrophages and granulocytes expressing L1 protein (calprotectin) in human Peyer's patches compared with normal ileal lamina propria and mesenteric lymph nodes.

    K Bjerke;T S Halstensen;F Jahnsen;K Pulford

  • Interleukin-8 in Serum and Cerebrospinal Fluid from Patients with Meningococcal Disease

    Alfred Halstensen;Miroslav Ceska;Petter Brandtzaeg;Heinz Redl

  • Heterogeneity of M-cell-associated B and T cells in human Peyer's patches.

    I N Farstad;T S Halstensen;O Fausa;P Brandtzaeg

Frequent Co-Authors

Peter Kierulf
Peter Kierulf Oslo University Hospital
Tom Eirik Mollnes
Tom Eirik Mollnes Oslo University Hospital
Helge Scott
Helge Scott University of Oslo
Ernst Arne Høiby
Ernst Arne Høiby Norwegian Institute of Public Health
Stig S. Frøland
Stig S. Frøland University of Oslo
Frode L. Jahnsen
Frode L. Jahnsen Oslo University Hospital
Finn-Eirik Johansen
Finn-Eirik Johansen University of Oslo
Terje Espevik
Terje Espevik Norwegian University of Science and Technology
Ludvig M. Sollid
Ludvig M. Sollid Oslo University Hospital
Guttorm Haraldsen
Guttorm Haraldsen Oslo University Hospital

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