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John H. Alexander

John H. Alexander

D-Index & Metrics

Medicine

D-Index
102
Citations
44410
World Ranking
7578
National Ranking
3952

Overview

John H. Alexander is affiliated with Duke University in the United States and has contributed extensively to the field of medicine, with a particular focus on cardiology and cardiovascular medicine. The breadth of their research spans several subfields including surgery, endocrinology, diabetes and metabolism, civil and structural engineering, and hematology.

The areas of research that dominate their work include:

  • Atrial Fibrillation Management and Outcomes
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Acute Myocardial Infarction Research
  • Cardiac Arrhythmias and Treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac Imaging and Diagnostics
  • Erythropoietin and Anemia Treatment

John H. Alexander's recent papers reflect an active engagement with contemporary cardiovascular and hematological topics, often intersecting with COVID-19 research:

  • Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial, 2021, published in The Lancet
  • Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19, 2021, published in JAMA
  • 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines, 2025, published in Circulation
  • Rivaroxaban in Patients with Atrial Fibrillation and a Bioprosthetic Mitral Valve, 2020, published in New England Journal of Medicine
  • Effect of Antithrombotic Therapy on Clinical Outcomes in Outpatients With Clinically Stable Symptomatic COVID-19, 2021, published in JAMA

Collaboration has been a notable aspect of their work, with frequent co-authors including Renato D. Lópes, Christopher B. Granger, Shaun G. Goodman, Daniel Wojdyla, and Lars Wallentin. The collaborations indicate significant engagement with other researchers in cardiovascular medicine.

Their research has been published in multiple well-known venues within the cardiovascular and medical community, including:

  • Circulation
  • Journal of the American College of Cardiology
  • American Heart Journal
  • European Heart Journal
  • JAMA Cardiology

Best Publications

  • Apixaban versus Warfarin in Patients with Atrial Fibrillation

    Christopher B. Granger;John H. Alexander;Renato D. Lopes;Elaine M. Hylek

  • Apixaban with Antiplatelet Therapy after Acute Coronary Syndrome

    John H. Jh Alexander;RD D Renato D. Rd Renato D Lopes;Stefan James;Rakhi Kilaru

  • Prasugrel versus clopidogrel for acute coronary syndromes without revascularization

    Matthew T. Roe;Paul W. Armstrong;Keith A.A. Fox;Harvey D. White

  • Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation

    R.D. Lopes;G. Heizer;R. Aronson;A.N. Vora

  • Effect of Linagliptin vs Placebo on Major Cardiovascular Events in Adults With Type 2 Diabetes and High Cardiovascular and Renal Risk: The CARMELINA Randomized Clinical Trial.

    Julio Rosenstock;Vlado Perkovic;Odd Erik Johansen;Mark E. Cooper

  • Efficacy of apixaban when compared with warfarin in relation to renal function in patients with atrial fibrillation: insights from the ARISTOTLE trial.

    Stefan H. Hohnloser;Ziad Hijazi;Laine Thomas;John H. Alexander

  • Apixaban, an oral, direct, selective factor Xa inhibitor, in combination with antiplatelet therapy after acute coronary syndrome: results of the Apixaban for Prevention of Acute Ischemic and Safety Events (APPRAISE) trial.

    Investigators;John H Alexander;Richard C Becker

  • Apixaban for Reduction In Stroke and Other ThromboemboLic Events in Atrial Fibrillation (ARISTOTLE) trial: Design and rationale

    Renato D. Lopes;John H. Alexander;Sana M. Al-Khatib;Jack Ansell

  • The novel biomarker-based ABC (age, biomarkers, clinical history)-bleeding risk score for patients with atrial fibrillation: a derivation and validation study

    Ziad Hijazi;Jonas Oldgren;Johan Lindbäck;John H Alexander

  • Therapeutic versus prophylactic anticoagulation for patients admitted to hospital with COVID-19 and elevated D-dimer concentration (ACTION): an open-label, multicentre, randomised, controlled trial.

    Renato D Lopes;Pedro Gabriel Melo de Barros e Silva;Remo H M Furtado;Ariane Vieira Scarlatelli Macedo

  • Surgical Treatment of Moderate Ischemic Mitral Regurgitation

    Peter K. Smith;John D. Puskas;Deborah D. Ascheim;Pierre Voisine

  • The ABC (age, biomarkers, clinical history) stroke risk score: a biomarker-based risk score for predicting stroke in atrial fibrillation

    Ziad Hijazi;Johan Lindbäck;John H. Alexander;Michael Hanna

  • Major Bleeding in Patients With Atrial Fibrillation Receiving Apixaban or Warfarin: The ARISTOTLE Trial (Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation): Predictors, Characteristics, and Clinical Outcomes

    Elaine M. Hylek;Claes Held;John H. Alexander;Renato D. Lopes

  • Endoscopic versus Open Vein-Graft Harvesting in Coronary-Artery Bypass Surgery

    Renato D. Lopes;Gail E. Hafley;Keith B. Allen;T. Bruce Ferguson

  • Saphenous Vein Graft Failure After Coronary Artery Bypass Surgery: Pathophysiology, Management, and Future Directions

    Ralf E. Harskamp;Renato D. Lopes;Clinton E. Baisden;Robbert J. de Winter

  • Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial.

    Triumph Investigators;John H Alexander;Harmony R Reynolds;Amanda L Stebbins

  • Apixaban compared with warfarin in patients with atrial fibrillation and previous stroke or transient ischaemic attack: a subgroup analysis of the ARISTOTLE trial.

    J Donald Easton;Renato D Lopes;M Cecilia Bahit;Daniel M Wojdyla

  • Growth Differentiation Factor 15, a Marker of Oxidative Stress and Inflammation, for Risk Assessment in Patients With Atrial Fibrillation Insights From the Apixaban for Reduction in Stroke and Other Thromboembolic Events in Atrial Fibrillation (ARISTOTLE) Trial

    Lars Wallentin;Ziad Hijazi;Ulrika Andersson;John H. Alexander

  • Effect of Discontinuing vs Continuing Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers on Days Alive and Out of the Hospital in Patients Admitted With COVID-19: A Randomized Clinical Trial.

    Renato D Lopes;Ariane V S Macedo;Pedro G M de Barros E Silva;Renata J Moll-Bernardes

  • Association of Myocardial Enzyme Elevation and Survival Following Coronary Artery Bypass Graft Surgery

    Michael J. Domanski;Kenneth Mahaffey;Vic Hasselblad;Sorin J. Brener

Frequent Co-Authors

Renato D. Lopes
Renato D. Lopes Duke University
Christopher B. Granger
Christopher B. Granger Duke University
Lars Wallentin
Lars Wallentin Uppsala University
Robert A. Harrington
Robert A. Harrington Cornell University
Michael G. Hanna
Michael G. Hanna University College London
Elaine M. Hylek
Elaine M. Hylek Boston University
Robert M. Califf
Robert M. Califf Duke University
Sana M. Al-Khatib
Sana M. Al-Khatib Duke University
Kenneth W. Mahaffey
Kenneth W. Mahaffey Stanford University
Richard C. Becker
Richard C. Becker University of Cincinnati

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