Daniel Rauh

Overview

Best Publications

• Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

  Martin Peifer;Lynnette Fernández-Cuesta;Martin L. Sos;Julie George

  1542
  Citations

• Frequent and Focal FGFR1 Amplification Associates with Therapeutically Tractable FGFR1 Dependency in Squamous Cell Lung Cancer

  Jonathan Weiss;Martin L. Sos;Danila Seidel;Martin Peifer

  1003
  Citations

• Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

  Peter S. Hammerman;Martin L. Sos;Alex H. Ramos;Chunxiao Xu

  593
  Citations

• Highly enantioselective synthesis and cellular evaluation of spirooxindoles inspired by natural products

  Andrey P. Antonchick;Claas Gerding-Reimers;Mario Catarinella;Markus Schürmann

  588
  Citations

• Small-molecule inhibition of APT1 affects Ras localization and signaling

  Frank J Dekker;Oliver Rocks;Nachiket Vartak;Sascha Menninger

  441
  Citations

• Identification of Thiazolidinones Spiro-Fused to Indolin-2-ones as Potent and Selective Inhibitors of the Mycobacterium tuberculosis Protein Tyrosine Phosphatase B

  Viktor V. Vintonyak;Karin Warburg;Holger Kruse;Stefan Grimme

  392
  Citations

• Predicting drug susceptibility of non–small cell lung cancers based on genetic lesions

  Martin L. Sos;Kathrin Michel;Thomas Zander;Jonathan Weiss

  339
  Citations

• Natural-product-derived fragments for fragment-based ligand discovery.

  Björn Over;Stefan Wetzel;Christian Grütter;Yasushi Nakai

  312
  Citations

• An unbiased cell morphology-based screen for new, biologically active small molecules.

  Masahiro Tanaka;Raynard Bateman;Daniel Rauh;Eugeni Vaisberg

  309
  Citations

• Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer

  Martin L. Sos;Stefanie Fischer;Roland Ullrich;Martin Peifer

  302
  Citations

• Interactive exploration of chemical space with Scaffold Hunter.

  Stefan Wetzel;Karsten Klein;Steffen Renner;Daniel Rauh

  266
  Citations

• Chemogenomic Profiling Provides Insights into the Limited Activity of Irreversible EGFR Inhibitors in Tumor Cells Expressing the T790M EGFR Resistance Mutation

  Martin L Sos;Haridas B. Rode;Stefanie Heynck;Martin Peifer

  254
  Citations

• Strategies for the Selective Regulation of Kinases with Allosteric Modulators: Exploiting Exclusive Structural Features

  Zhizhou Fang;Christian Grütter;Daniel Rauh

  249
  Citations

• Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

  Jimmy A Blair;Daniel Rauh;Charles Kung;Cai-Hong Yun

  234
  Citations

• Tumor VEGF:VEGFR2 autocrine feed-forward loop triggers angiogenesis in lung cancer

  Sampurna Chatterjee;Lukas C. Heukamp;Maike Siobal;Jakob Schöttle

  230
  Citations

• BSKs are partially redundant positive regulators of brassinosteroid signaling in Arabidopsis.

  Shivakumar Sreeramulu;Yana Mostizky;Sukumaran Sunitha;Eilon Shani

  224
  Citations

• ALK Mutations Conferring Differential Resistance to Structurally Diverse ALK Inhibitors

  Johannes M. Heuckmann;Michael Hölzel;Martin L. Sos;Stefanie Heynck

  213
  Citations

• A framework for identification of actionable cancer genome dependencies in small cell lung cancer.

  Martin L. Sos;Felix Dietlein;Felix Dietlein;Martin Peifer;Martin Peifer;Jakob Schöttle;Jakob Schöttle

  209
  Citations

• Development of a fluorescent-tagged kinase assay system for the detection and characterization of allosteric kinase inhibitors.

  Jeffrey R. Simard;Matthäus Getlik;Christian Grütter;Vijaykumar Pawar

  208
  Citations

• Hybrid compound design to overcome the gatekeeper T338M mutation in cSrc

  Matthäus Getlik;Christian Grütter;Jeffrey R. Simard;Sabine Klüter

  189
  Citations