World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
68
Citations
15166
World Ranking
6586
National Ranking
1169

Overview

Gong Chen is affiliated with Nankai University in China and has contributed extensively to the fields of chemistry and medicine. Their research work spans over 152 publications in chemistry and 147 in medicine, with a strong focus on organic chemistry and molecular biology among other disciplines.

The scientist's main subfields of study include:

  • Organic Chemistry
  • Molecular Biology
  • Oncology
  • Pulmonary and Respiratory Medicine
  • Epidemiology

The primary topics of research involve catalytic methods and chemical synthesis, alongside applications in biological and medical management. Specific areas covered are:

  • Catalytic C-H Functionalization Methods
  • Chemical Synthesis and Analysis
  • Synthesis and Catalytic Reactions
  • Click Chemistry and Applications
  • Acute Ischemic Stroke Management
  • Sulfur-Based Synthesis Techniques
  • Radical Photochemical Reactions

Gong Chen's recent papers illustrate a focus on immunotherapy, synthetic chemistry, and oncology-related topics, including the following:

  • Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study, 2022, Cell Research
  • Nitrene-mediated intermolecular N-N coupling for efficient synthesis of hydrazides, 2021, Nature Chemistry
  • Iron-catalysed reductive cross-coupling of glycosyl radicals for the stereoselective synthesis of C-glycosides, 2022, Nature Synthesis
  • The watch-and-wait strategy versus surgical resection for rectal cancer patients with a clinical complete response after neoadjuvant chemoradiotherapy, 2021, Radiation Oncology
  • Stereoselective Synthesis of C-Vinyl Glycosides via Palladium-Catalyzed C−H Glycosylation of Alkenes, 2021, Angewandte Chemie International Edition

The scientist has published frequently in certain venues, indicating recurring contributions to specific journals and platforms:

  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature (17 publications)
  • Organic Letters (9 publications)
  • Angewandte Chemie International Edition (7 publications)
  • Angewandte Chemie (7 publications)
  • Journal of the American Chemical Society (6 publications)

Collaboration is a notable aspect of Gong Chen's work, with frequent coauthors including:

  • Gang He (45 coauthored papers)
  • Bo Li (16 coauthored papers)
  • Xin Chu (15 coauthored papers)
  • Hao Wang (11 coauthored papers)
  • Chuanzheng Zhou (10 coauthored papers)

Best Publications

  • Highly efficient syntheses of azetidines, pyrrolidines, and indolines via palladium catalyzed intramolecular amination of C(sp3)-H and C(sp2)-H bonds at γ and δ positions.

    Gang He;Yingsheng Zhao;Shuyu Zhang;Chengxi Lu

  • A Practical Strategy for the Structural Diversification of Aliphatic Scaffolds through the Palladium-Catalyzed Picolinamide-Directed Remote Functionalization of Unactivated C(sp3) ? H Bonds

    Gang He;Gong Chen

  • Syntheses and Transformations of α-Amino Acids via Palladium-Catalyzed Auxiliary-Directed sp3 C–H Functionalization

    Gang He;Bo Wang;William A. Nack;Gong Chen;Gong Chen

  • Total synthesis of celogentin C by stereoselective C-H activation.

    Yiqing Feng;Gong Chen

  • Palladium-Catalyzed Picolinamide-Directed Alkylation of Unactivated C(sp3)–H Bonds with Alkyl Iodides

    Shu Yu Zhang;Gang He;William A. Nack;Yingsheng Zhao

  • Use of a Readily Removable Auxiliary Group for the Synthesis of Pyrrolidones by the Palladium‐Catalyzed Intramolecular Amination of Unactivated γ C(sp3) ? H Bonds

    Gang He;Shu Yu Zhang;William A. Nack;Qiong Li

  • Efficient Alkyl Ether Synthesis via Palladium-Catalyzed, Picolinamide-Directed Alkoxylation of Unactivated C(sp3)–H and C(sp2)–H Bonds at Remote Positions

    Shu Yu Zhang;Gang He;Yingsheng Zhao;Kiwan Wright

  • Stereoselective Synthesis of β-Alkylated α-Amino Acids via Palladium-Catalyzed Alkylation of Unactivated Methylene C(sp3)–H Bonds with Primary Alkyl Halides

    Shu Yu Zhang;Qiong Li;Gang He;William A. Nack

  • Photoredox-mediated Minisci C–H alkylation of N-heteroarenes using boronic acids and hypervalent iodine

    Guo Xing Li;Christian A. Morales-Rivera;Yaxin Wang;Fang Gao

  • Halogen-Bond-Promoted Photoactivation of Perfluoroalkyl Iodides: A Photochemical Protocol for Perfluoroalkylation Reactions

    Yaxin Wang;Junhua Wang;Guo Xing Li;Gang He

  • Tonic inhibition in dentate gyrus impairs long- term potentiation and memory in an Alzhiemer's disease model

    Zheng Wu;Ziyuan Guo;Marla Gearing;Gong Chen

  • A general strategy for synthesis of cyclophane-braced peptide macrocycles via palladium-catalysed intramolecular sp 3 C-H arylation

    Xuekai Zhang;Gang Lu;Meng Sun;Madhu Mahankali

  • Novel magnetic MnO2/MnFe2O4 nanocomposite as a heterogeneous catalyst for activation of peroxymonosulfate (PMS) toward oxidation of organic pollutants

    Unknown

  • Copper-catalyzed carboxamide-directed ortho amination of anilines with alkylamines at room temperature.

    Qiong Li;Shu Yu Zhang;Gang He;Zhaoyan Ai

  • Diameter-selective resonant Raman scattering in double-wall carbon nanotubes

    S. Bandow;G. Chen;G. U. Sumanasekera;R. Gupta

  • Palladium-Catalyzed Alkylation of ortho-C(sp2)–H Bonds of Benzylamide Substrates with Alkyl Halides

    Yingsheng Zhao;Gong Chen

  • Iridium-Catalyzed Enantioselective C(sp 3 )-H Amidation Controlled by Attractive Noncovalent Interactions

    Hao Wang;Yoonsu Park;Ziqian Bai;Sukbok Chang

  • A visible-light-promoted radical reaction system for azidation and halogenation of tertiary aliphatic C-H bonds

    Yaxin Wang;Guo Xing Li;Guohui Yang;Gang He

  • Histidine-Specific Peptide Modification via Visible-Light-Promoted C-H Alkylation.

    Xiaoping Chen;Farong Ye;Xiaosheng Luo;Xueyi Liu

  • Palladium-Catalyzed Amide-Directed Enantioselective Hydrocarbofunctionalization of Unactivated Alkenes Using a Chiral Monodentate Oxazoline Ligand

    Hao Wang;Zibo Bai;Tangqian Jiao;Zhiqiang Deng

  • Building Complex Glycopeptides: Development of a Cysteine‐Free Native Chemical Ligation Protocol

    Bin Wu;Jiehao Chen;J. David Warren;Gong Chen

  • Palladium-catalyzed trifluoroacetate-promoted mono-arylation of the β-methyl group of alanine at room temperature: synthesis of β-arylated α-amino acids through sequential C–H functionalization

    Bo Wang;William A. Nack;Gang He;Shu Yu Zhang

  • An Enantioselective Bidentate Auxiliary Directed Palladium-Catalyzed Benzylic C−H Arylation of Amines Using a BINOL Phosphate Ligand

    Hao Wang;Hua Rong Tong;Gang He;Gong Chen;Gong Chen

  • Anticancer Peptidylarginine Deiminase (PAD) Inhibitors Regulate the Autophagy Flux and the Mammalian Target of Rapamycin Complex 1 Activity

    Yuji Wang;Yuji Wang;Pingxin Li;Shu Wang;Jing Hu

  • Improved Protocol for Indoline Synthesis via Palladium-Catalyzed Intramolecular C(sp2)–H Amination

    Gang He;Chengxi Lu;Yingsheng Zhao;William A. Nack

Frequent Co-Authors

Shu-Yu Zhang
Shu-Yu Zhang Shanghai Jiao Tong University
Samuel J. Danishefsky
Samuel J. Danishefsky Columbia University
Peng Liu
Peng Liu University of Pittsburgh
Yanming Wang
Yanming Wang Shanghai Jiao Tong University
Tom L. Richard
Tom L. Richard Pennsylvania State University
Dalibor Sames
Dalibor Sames Columbia University
Qian Peng
Qian Peng Chinese Academy of Sciences
Marla Gearing
Marla Gearing Emory University
Sukbok Chang
Sukbok Chang Korea Advanced Institute of Science and Technology
B. Franklin Pugh
B. Franklin Pugh Cornell University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students pursuing Chemistry in the USA, exploring related fields such as forensic science can open up diverse career opportunities. The realm of forensic science careers merges chemical knowledge with investigative work, making it an exciting path for those interested in applying chemistry to real-world problems.

Considering educational pathways, many students opt for flexible online programs. Understanding the criminal justice degree cost is crucial when planning for online studies, as fees can vary widely depending on the institution and program level.

If you're looking for accessible entry points, some of the best online associates in criminal justice offer foundational knowledge that complements chemistry-focused careers, particularly in law enforcement or regulatory agencies.

Additionally, roles such as paralegals benefit from a grasp of scientific terminology and evidence handling. Exploring paralegal salary trends can help students understand the financial prospects in legal support positions linked to scientific fields.

Best Scientists Citing Gong Chen

Trending Scientists

Recently Published Articles