World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
69
Citations
15508
World Ranking
6267
National Ranking
1909

Biology and Biochemistry

D-Index
81
Citations
22764
World Ranking
3913
National Ranking
1934

Overview

Paul R. Thompson is affiliated with the University of Massachusetts Chan Medical School in the United States. Their research spans multiple areas within medicine, biochemistry, genetics, and molecular biology.

The scientist's main fields of study include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Subfields of focus encompass:

  • Molecular Biology
  • Immunology
  • Oncology
  • Cancer Research
  • Immunology and Allergy

Key topics in their work cover:

  • Signaling Pathways in Disease
  • Peptidase Inhibition and Analysis
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Cell Adhesion Molecules Research
  • Protease and Inhibitor Mechanisms
  • Inflammasome and immune disorders
  • Interferon and immune responses

Frequent coauthors collaborating with Paul R. Thompson include:

  • Santanu Mondal
  • Leonard Barasa
  • Ronak Tilvawala
  • Janneke D. Icso
  • Venkatesh V. Nemmara

The scientist regularly publishes in several venues, with notable frequency in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biochemistry
  • Journal of the American Chemical Society
  • International Journal of Molecular Sciences
  • Current Opinion in Chemical Biology

Recent publications by Paul R. Thompson include:

  • Succination inactivates gasdermin D and blocks pyroptosis, 2020, Science
  • Citrullinated vimentin mediates development and progression of lung fibrosis, 2021, Science Translational Medicine
  • Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188, 2021, Viruses
  • PADI2-Catalyzed MEK1 Citrullination Activates ERK1/2 and Promotes IGF2BP1-Mediated SOX2 mRNA Stability in Endometrial Cancer, 2021, Advanced Science
  • Targeting STING oligomerization with small-molecule inhibitors, 2023, Proceedings of the National Academy of Sciences

Best Publications

  • NETs Are a Source of Citrullinated Autoantigens and Stimulate Inflammatory Responses in Rheumatoid Arthritis

    Ritika Khandpur;Carmelo Carmona-Rivera;Anuradha Vivekanandan-Giri;Alison Gizinski

  • Diverse stimuli engage different neutrophil extracellular trap pathways

    Elaine F Kenny;Alf Herzig;Renate Krüger;Aaron Muth

  • Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

    Huw D Lewis;John Liddle;Jim E Coote;Stephen J Atkinson

  • Succination inactivates gasdermin D and blocks pyroptosis

    Fiachra Humphries;Liraz Shmuel-Galia;Natalia Ketelut-Carneiro;Sheng Li

  • Dexamethasone and pentoxifylline inhibit endotoxin-induced cachectin/tumor necrosis factor synthesis at separate points in the signaling pathway.

    J Han;P Thompson;B Beutler

  • The structural basis of protein acetylation by the p300/CBP transcriptional coactivator

    Xin Liu;Ling Wang;Kehao Zhao;Kehao Zhao;Paul R. Thompson;Paul R. Thompson

  • Regulation of the p300 HAT domain via a novel activation loop

    Paul R Thompson;Paul R Thompson;Dongxia Wang;Ling Wang;Marcella Fulco

  • Peptidylarginine Deiminase Inhibition Reduces Vascular Damage and Modulates Innate Immune Responses in Murine Models of Atherosclerosis

    Jason S. Knight;Wei Luo;Alexander A. O’Dell;Srilakshmi Yalavarthi

  • Peptidylarginine deiminase inhibition disrupts NET formation and protects against kidney, skin and vascular disease in lupus-prone MRL/lpr mice

    Jason S Knight;Venkataraman Subramanian;Alexander A O'Dell;Srilakshmi Yalavarthi

  • Activation of PAD4 in NET formation

    Amanda S. Rohrbach;Daniel J. Slade;Paul R. Thompson;Kerri A. Mowen

  • Peptidylarginine deiminase inhibition is immunomodulatory and vasculoprotective in murine lupus

    Jason S. Knight;Wenpu Zhao;Wei Luo;Venkataraman Subramanian

  • Inhibitors and Inactivators of Protein Arginine Deiminase 4: Functional and Structural Characterization

    Yuan Luo;Kyouhei Arita;Monica Bhatia;Bryan Knuckley

  • Chemical biology of protein arginine modifications in epigenetic regulation.

    Jakob Fuhrmann;Kathleen W. Clancy;Paul R. Thompson

  • N-α-Benzoyl-N5-(2-Chloro-1-Iminoethyl)-l-Ornithine Amide, a Protein Arginine Deiminase Inhibitor, Reduces the Severity of Murine Collagen-Induced Arthritis

    Van C. Willis;Alison M. Gizinski;Nirmal K. Banda;Corey P. Causey

  • Protein Arginine Deiminases and Associated Citrullination: Physiological Functions and Diseases Associated with Dysregulation.

    Erin E. Witalison;Paul R. Thompson;Lorne J. Hofseth

  • A saturable transport mechanism in the intestinal absorption of gabapentin is the underlying cause of the lack of proportionality between increasing dose and drug levels in plasma.

    Unknown

  • Structure of an Enzyme Required for Aminoglycoside Antibiotic Resistance Reveals Homology to Eukaryotic Protein Kinases

    Wai-Ching Hon;Geoffrey A. McKay;Paul R. Thompson;Robert M. Sweet

  • Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.

    Carmelo Carmona-Rivera;Philip M. Carlucci;Erica Moore;Nithya Lingampalli;Nithya Lingampalli

  • Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4

    Pingxin Li;Hongjie Yao;Zhiqiang Zhang;Ming Li

  • Protein arginine deiminase 4 (PAD4): current understanding and future therapeutic potential

    Justin E Jones;Corey P Causey;Bryan Knuckley;Jessica L Slack-Noyes

  • The protein arginine deiminases: Structure, function, inhibition, and disease.

    Kevin L. Bicker;Paul R. Thompson

Frequent Co-Authors

Scott A. Coonrod
Scott A. Coonrod Cornell University
Eranthie Weerapana
Eranthie Weerapana Boston College
Gerard D. Wright
Gerard D. Wright McMaster University
Mariana J. Kaplan
Mariana J. Kaplan National Institutes of Health
Philip A. Cole
Philip A. Cole Brigham and Women's Hospital
Thomas Arnesen
Thomas Arnesen University of Bergen
I-Cheng Ho
I-Cheng Ho Brigham and Women's Hospital
Jason S. Knight
Jason S. Knight University of Michigan–Ann Arbor
William H. Robinson
William H. Robinson Stanford University
Patrick J. Venables
Patrick J. Venables University of Oxford

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring Biology and Biochemistry opens the door to a range of online degree programs and certification pathways in the USA. Many students interested in life sciences also consider healthcare and allied health careers, and online education offers flexible options to gain credentials.

For those drawn to human performance, an exercise science degree online accredited can lead to roles in fitness, wellness, and rehabilitation settings. Similarly, pursuing an online bachelor's in kinesiology provides foundational knowledge for careers in movement science, sports medicine, and physical therapy fields.

Graduates looking to specialize further in healthcare can explore nursing-focused options. Programs like pmhnp online programs prepare registered nurses for practice in psychiatric mental health, while a post masters fnp certification helps nurses become family nurse practitioners ready for advanced clinical roles.

These online pathways provide students from biology and biochemistry backgrounds with practical options to advance their education and unlock diverse career opportunities in science and healthcare fields.

Best Scientists Citing Paul R. Thompson

Trending Scientists