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Eranthie Weerapana

Eranthie Weerapana

D-Index & Metrics

Chemistry

D-Index
57
Citations
12683
World Ranking
11012
National Ranking
3011

Overview

Eranthie Weerapana is affiliated with Boston College in the United States and has an extensive research portfolio primarily in the fields of biochemistry, genetics, and molecular biology. Their work spans multiple subfields, including molecular biology, organic chemistry, nutrition and dietetics, oncology, and cell biology.

Their research topics cover a range of areas, such as:

  • Click Chemistry and Applications
  • Trace Elements in Health
  • Peptidase Inhibition and Analysis
  • Biotin and Related Studies
  • Redox Biology and Oxidative Stress
  • Metalloenzymes and Iron-Sulfur Proteins
  • S100 Proteins and Annexins

They have contributed to publications in several venues, most frequently in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • ACS Chemical Biology
  • Nature Chemical Biology
  • Cell Chemical Biology
  • Nature Communications

Some of their recent published works include:

  • Genetically encoded protein sulfation in mammalian cells, 2020, Nature Chemical Biology
  • Proteomic characterization of the Toxoplasma gondii cytokinesis machinery portrays an expanded hierarchy of its assembly and function, 2022, Nature Communications
  • The Antimalarial Natural Product Salinipostin A Identifies Essential α/β Serine Hydrolases Involved in Lipid Metabolism in P. falciparum Parasites, 2020, Cell Chemical Biology
  • Monitoring Fe-S cluster occupancy across the E. coli proteome using chemoproteomics, 2023, Nature Chemical Biology
  • Profiling Cysteine Reactivity and Oxidation in the Endoplasmic Reticulum, 2020, ACS Chemical Biology

Frequent collaborators in their research include:

  • Daniel W. Bak
  • Qianni Peng
  • Abhishek Chatterjee
  • Julia A. Falco
  • Aaron Maurais

Best Publications

  • Quantitative reactivity profiling predicts functional cysteines in proteomes

    Eranthie Weerapana;Chu Wang;Gabriel M. Simon;Florian Richter

  • Optimized Metal-Organic-Framework Nanospheres for Drug Delivery: Evaluation of Small-Molecule Encapsulation

    Jia Zhuang;Chun Hong Kuo;Lien Yang Chou;De Yu Liu

  • Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

    Kay Ahn;Douglas S. Johnson;Mauro Mileni;David Beidler

  • Asparagine-linked protein glycosylation: from eukaryotic to prokaryotic systems.

    Eranthie Weerapana;Barbara Imperiali

  • Strategies for discovering and derisking covalent, irreversible enzyme inhibitors

    Douglas S Johnson;Eranthie Weerapana;Benjamin F Cravatt

  • A chemoproteomic platform to quantitatively map targets of lipid-derived electrophiles.

    Chu Wang;Eranthie Weerapana;Megan M Blewett;Benjamin F Cravatt

  • Tandem orthogonal proteolysis-activity-based protein profiling (TOP-ABPP)—a general method for mapping sites of probe modification in proteomes

    Eranthie Weerapana;Anna E Speers;Benjamin F Cravatt

  • Mechanistic and Pharmacological Characterization of PF-04457845: A Highly Potent and Selective Fatty Acid Amide Hydrolase Inhibitor That Reduces Inflammatory and Noninflammatory Pain

    Kay Ahn;Sarah E. Smith;Marya B. Liimatta;David Beidler

  • Disparate proteome reactivity profiles of carbon electrophiles

    Eranthie Weerapana;Gabriel M Simon;Benjamin F Cravatt

  • MsrB1 and MICALs Regulate Actin Assembly and Macrophage Function via Reversible Stereoselective Methionine Oxidation

    Byung Cheon Lee;Zalán Péterfi;Fu Kun W. Hoffmann;Richard E. Moore

  • Zinc-binding cysteines: diverse functions and structural motifs.

    Nicholas J. Pace;Eranthie Weerapana

  • Diverse compounds from pleuromutilin lead to a thioredoxin inhibitor and inducer of ferroptosis

    Evijola Llabani;Robert W. Hicklin;Hyang Yeon Lee;Stephen E. Motika

  • Covalent protein modification: the current landscape of residue-specific electrophiles

    D Alexander Shannon;Eranthie Weerapana

  • From structure to redox: The diverse functional roles of disulfides and implications in disease

    Tyler J. Bechtel;Eranthie Weerapana

  • Diverse functional roles of reactive cysteines.

    Nicholas J. Pace;Eranthie Weerapana

  • The Rheumatoid Arthritis-Associated Citrullinome

    Ronak Tilvawala;Son Hong Nguyen;Aaron J. Maurais;Venkatesh V. Nemmara

  • GSTP1 Is a Driver of Triple-Negative Breast Cancer Cell Metabolism and Pathogenicity

    Sharon M. Louie;Elizabeth A. Grossman;Lisa A. Crawford;Lucky Ding

  • Reactive-cysteine profiling for drug discovery

    Aaron J Maurais;Eranthie Weerapana

  • In vitro assembly of the undecaprenylpyrophosphate-linked heptasaccharide for prokaryotic N-linked glycosylation

    Kerney Jebrell Glover;Eranthie Weerapana;Barbara Imperiali

  • Investigating the Proteome Reactivity and Selectivity of Aryl Halides

    D. Alexander Shannon;Ranjan Banerjee;Elizabeth R. Webster;Daniel W. Bak

  • Direct biochemical evidence for the utilization of UDP-bacillosamine by PglC, an essential glycosyl-1-phosphate transferase in the Campylobacter jejuni N-linked glycosylation pathway.

    Kerney Jebrell Glover;Eranthie Weerapana;Mark M. Chen;Barbara Imperiali

Frequent Co-Authors

Benjamin F. Cravatt
Benjamin F. Cravatt Scripps Research Institute
Matthew Bogyo
Matthew Bogyo Stanford University
W. Marston Linehan
W. Marston Linehan National Institutes of Health
Markus Kaiser
Markus Kaiser University of Duisburg-Essen
I-Cheng Ho
I-Cheng Ho Brigham and Women's Hospital
Lizbeth Hedstrom
Lizbeth Hedstrom Brandeis University
Renier A. L. van der Hoorn
Renier A. L. van der Hoorn University of Oxford
Matthew K. Waldor
Matthew K. Waldor Harvard Medical School
Vadim N. Gladyshev
Vadim N. Gladyshev Brigham and Women's Hospital

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