World's Best Scientists 2026 revealed!
Joseph R. Casey

Joseph R. Casey

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
10397
World Ranking
16142
National Ranking
563

Overview

Joseph R. Casey is affiliated with the University of Alberta in Canada, focusing primarily on medical research with a concentration in cardiology and cardiovascular medicine, radiology, nuclear medicine and imaging, surgery, physiology, and ophthalmology.

Their recent research contributions include studies published in a range of scientific venues such as Biochimica et Biophysica Acta (BBA) - Biomembranes, Circulation, Reviews of Physiology, Biochemistry and Pharmacology, Biochemical Pharmacology, and Scientific Reports.

Notable publications include:

  • Large conformational dynamics in Band 3 protein: Significance for erythrocyte senescence signalling (2021) in Biochimica et Biophysica Acta (BBA) - Biomembranes
  • Molecular Mechanisms of Fuchs and Congenital Hereditary Endothelial Corneal Dystrophies (2020) in Reviews of Physiology, Biochemistry and Pharmacology
  • Human red blood cell uptake and sequestration of arsenite and selenite: Evidence of seleno-bis(S-glutathionyl) arsinium ion formation in human cells (2020) in Biochemical Pharmacology
  • Altered gene expression in slc4a11−/− mouse cornea highlights SLC4A11 roles (2021) in Scientific Reports
  • SLICE-CEA CardioLink-8: A Randomized Trial of Evolocumab on Carotid Artery Atherosclerotic Plaque Characteristics in Asymptomatic High-Risk Carotid Stenosis (2025) in Circulation

The primary research areas covered in their work include:

  • Corneal surgery and disorders
  • Glaucoma and retinal disorders
  • Arsenic contamination and mitigation
  • Selenium in biological systems
  • Heavy metal exposure and toxicity
  • Peripheral artery disease management
  • Erythrocyte function and pathophysiology

Joseph R. Casey has collaborated frequently with a number of researchers, including:

  • Hwee Teoh
  • Subodh Verma
  • Adrian Quan
  • Michael Moroney
  • Gurnit Kaur

Their work spans multiple subfields of medicine, reflecting an interdisciplinary approach that integrates surgical practices, cardiovascular studies, imaging techniques, and ophthalmological research. This diverse scope supports investigations ranging from molecular and cellular mechanisms, such as erythrocyte function and heavy metal toxicity, to clinical trials focused on cardiovascular disease management.

Best Publications

  • Sensors and regulators of intracellular pH

    Joseph R. Casey;Sergio Grinstein;John Orlowski

  • A Transport Metabolon FUNCTIONAL INTERACTION OF CARBONIC ANHYDRASE II AND CHLORIDE/BICARBONATE EXCHANGERS

    Deborah Sterling;Reinhart A.F. Reithmeier;Joseph R. Casey

  • Mutations in sodium-borate cotransporter SLC4A11 cause recessive congenital hereditary endothelial dystrophy (CHED2)

    Eranga N Vithana;Patricio Morgan;Periasamy Sundaresan;Neil D Ebenezer

  • SLC4A11 mutations in Fuchs endothelial corneal dystrophy

    Eranga N. Vithana;Patricio E. Morgan;Vedam Ramprasad;Donald T.H. Tan

  • Carbonic anhydrase II binds to and enhances activity of the Na+/H+ exchanger

    Xiuju J. Li;Bernando Alvarez;Joseph R. Casey;Reinhart A. F. Reithmeier

  • Analysis of the oligomeric state of Band 3, the anion transport protein of the human erythrocyte membrane, by size exclusion high performance liquid chromatography. Oligomeric stability and origin of heterogeneity.

    J. R. Casey;R. A. F. Reithmeier

  • Band 3, the human red cell chloride/bicarbonate anion exchanger (AE1, SLC4A1), in a structural context.

    Reinhart A.F. Reithmeier;Joseph R. Casey;Antreas C. Kalli;Mark S.P. Sansom

  • Bicarbonate transport in cell physiology and disease.

    Emmanuelle Cordat;Joseph R. Casey

  • The extracellular component of a transport metabolon. Extracellular loop 4 of the human AE1 Cl-/HCO3- exchanger binds carbonic anhydrase IV

    Deborah Sterling;Bernardo V. Alvarez;Joseph R. Casey

  • Carbonic Anhydrase Inhibitors. Design of Selective, Membrane-Impermeant Inhibitors Targeting the Human Tumor-Associated Isozyme IX

    Joseph. R. Casey;Patricio E. Morgan;Daniela Vullo;Andrea Scozzafava

  • Direct extracellular interaction between carbonic anhydrase IV and the human NBC1 sodium/bicarbonate co-transporter.

    Bernardo V. Alvarez;Frederick B. Loiselle;Claudiu T. Supuran;George J. Schwartz

  • Novel Topology in C-terminal Region of the Human Plasma Membrane Anion Exchanger, AE1

    Quansheng Zhu;Diana W.K. Lee;Joseph R. Casey

  • Interactions of Transmembrane Carbonic Anhydrase, CAIX, with Bicarbonate Transporters

    Patricio Eduardo Morgan;Silvia Pastorekova;Alan K Stuart-Tilley;Seth L. Alper

  • Bicarbonate transporters in corals point towards a key step in the evolution of cnidarian calcification

    Didier Zoccola;Philippe Ganot;Anthony Bertucci;Natacha Caminiti-Segonds

  • Topology of the Membrane Domain of Human Erythrocyte Anion Exchange Protein, AE1

    Jocelyne Fujinaga;Xiao-Bo Tang;Joseph R. Casey

  • Metabolon disruption: a mechanism that regulates bicarbonate transport

    Bernardo V Alvarez;Gonzalo L Vilas;Joseph R Casey

  • A novel carbonic anhydrase II binding site regulates NHE1 activity

    Xiuju Li;Yongsheng Liu;Bernardo V. Alvarez;Joseph R. Casey

  • The functional and physical relationship between the DRA bicarbonate transporter and carbonic anhydrase II.

    Deborah Sterling;Nathan J. D. Brown;Claudiu T. Supuran;Joseph R. Casey

  • Transport activity of AE3 chloride/bicarbonate anion-exchange proteins and their regulation by intracellular pH.

    Deborah Sterling;Joseph R. Casey

  • Topology of the Region Surrounding Glu681 of Human AE1 Protein, the Erythrocyte Anion Exchanger

    Xiao-Bo Tang;Jocelyne Fujinaga;Ron Kopito;Joseph R. Casey

Frequent Co-Authors

Eranga N. Vithana
Eranga N. Vithana National University of Singapore
Tin Aung
Tin Aung National University of Singapore
Ron R. Kopito
Ron R. Kopito Stanford University
Claudiu T. Supuran
Claudiu T. Supuran University of Florence
James D. Young
James D. Young University of Alberta
Richard Zimmermann
Richard Zimmermann Saarland University
Donald T.H. Tan
Donald T.H. Tan National University of Singapore
Larry Fliegel
Larry Fliegel University of Alberta
Joachim W. Deitmer
Joachim W. Deitmer Technical University of Kaiserslautern
Kang Zhang
Kang Zhang Macau University of Science and Technology

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

If you’re interested in Biology and Biochemistry, a range of online degrees can help shape your future career. Many students start their healthcare journeys as medical assistants. Transitioning from a medical assistant role, you may want to explore medical assistant to LPN programs, designed to help you advance in the medical field quickly and efficiently.

For those seeking a strong foundation in life sciences, an online biology bachelor's degree offers coursework in genetics, ecology, and molecular biology—essential for roles in research, teaching, and healthcare. If nursing appeals to you, examine online ASN programs, which prepare graduates for registered nursing licensure and clinical practice.

Nutrition is another growing field with significant biochemistry applications. Accredited best online nutrition programs can lead to opportunities in wellness, dietetics, and food science. Whichever path you choose, flexible online options make it easier to advance your education while balancing other commitments.

Best Scientists Citing Joseph R. Casey

Trending Scientists