Xu Wu

Overview

Best Publications

• Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

  Jun Liu;Shifeng Pan;Mindy H. Hsieh;Nicholas Ng

  828
  Citations

• A Stem Cell–Based Approach to Cartilage Repair

  Kristen Johnson;Shoutian Zhu;Matthew S. Tremblay;Matthew S. Tremblay;Joshua N. Payette

  779
  Citations

• Interfering with Resistance to Smoothened Antagonists by Inhibition of the PI3K Pathway in Medulloblastoma

  Silvia Buonamici;Juliet Williams;Michael Morrissey;Anlai Wang

  539
  Citations

• Dedifferentiation of Lineage-Committed Cells by a Small Molecule

  Shuibing Chen;Qisheng Zhang;Xu Wu;Peter G. Schultz

  396
  Citations

• The Renewal and Differentiation of Isl1+ Cardiovascular Progenitors Are Controlled by a Wnt/β-Catenin Pathway

  Yibing Qyang;Silvia Martin-Puig;Murali Chiravuri;Shuibing Chen

  387
  Citations

• Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist

  Shifeng Pan;Xu Wu;Jiqing Jiang;Wenqi Gao

  356
  Citations

• Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

  Michael DeRan;Jiayi Yang;Che-Hung Shen;Eric C. Peters

  306
  Citations

• The inhalation anesthetic isoflurane increases levels of proinflammatory TNF-α, IL-6, and IL-1β

  Xu Wu;Yan Lu;Yan Lu;Yuanlin Dong;Guohua Zhang

  304
  Citations

• A Combinatorial Scaffold Approach toward Kinase-Directed Heterocycle Libraries

  Sheng Ding;Nathanael S. Gray;Xu Wu;Qiang Ding

  294
  Citations

• Small Molecules that Induce Cardiomyogenesis in Embryonic Stem Cells

  Xu Wu;Sheng Ding;Qiang Ding;Nathanael S Gray

  291
  Citations

• Identification of Serum-Derived Sphingosine-1-Phosphate as a Small Molecule Regulator of YAP

  Eric Miller;Jiayi Yang;Michael DeRan;Chunlei Wu

  284
  Citations

• Purmorphamine induces osteogenesis by activation of the hedgehog signaling pathway.

  Xu Wu;John Walker;Jie Zhang;Sheng Ding

  264
  Citations

• A small molecule with osteogenesis-inducing activity in multipotent mesenchymal progenitor cells.

  Xu Wu;Sheng Ding;Qiang Ding;Nathanael S. Gray

  256
  Citations

• The Mitochondrial Pathway of Anesthetic Isoflurane-induced Apoptosis *

  Yiying Zhang;Yiying Zhang;Yuanlin Dong;Xu Wu;Xu Wu;Yan Lu;Yan Lu

  253
  Citations

• Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathway

  PuiYee Chan;Xiao Han;Baohui Zheng;Michael DeRan

  248
  Citations

• Anesthetic sevoflurane causes neurotoxicity differently in neonatal naïve and Alzheimer disease transgenic mice.

  Yan Lu;Xu Wu;Yuanlin Dong;Zhipeng Xu

  225
  Citations

• Protein Lipidation in Cell Signaling and Diseases: Function, Regulation, and Therapeutic Opportunities.

  Baoen Chen;Yang Sun;Jixiao Niu;Gopala K. Jarugumilli

  212
  Citations

• A Small Molecule Primes Embryonic Stem Cells for Differentiation

  Shoutian Zhu;Heiko Wurdak;Jian Wang;Costas A. Lyssiotis

  198
  Citations

• Topical Treatment of Basal Cell Carcinomas in Nevoid Basal Cell Carcinoma Syndrome with a Smoothened Inhibitor

  Hans Skvara;Frank Kalthoff;Josef G. Meingassner;Barbara Wolff-Winiski

  195
  Citations

• Palmitoylation-dependent activation of MC1R prevents melanomagenesis.

  Shuyang Chen;Bo Zhu;Chengqian Yin;Wei Liu

  188
  Citations