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Biology and Biochemistry

D-Index
57
Citations
11978
World Ranking
13817
National Ranking
385

Overview

Walter G. Thomas is affiliated with the University of Queensland in Australia and has an extensive research portfolio primarily within the fields of Medicine and Biochemistry, Genetics and Molecular Biology.

Their research encompasses several interconnected subfields, including Molecular Biology, Cardiology and Cardiovascular Medicine, Biomedical Engineering, Nutrition and Dietetics, and Epidemiology.

Main topics addressed in their work include:

  • Receptor Mechanisms and Signaling
  • Biochemical Analysis and Sensing Techniques
  • Cardiac Fibrosis and Remodeling
  • Apelin-related Biomedical Research
  • Ion Transport and Channel Regulation
  • Heart Failure Treatment and Management
  • RNA and Protein Synthesis Mechanisms

Walter G. Thomas has published across a range of respected venues, with notable frequency in:

  • IUPHAR/BPS Guide to Pharmacology CITE
  • Heart Lung and Circulation
  • Biochemical Pharmacology
  • Proceedings of the National Academy of Sciences
  • Circulation

Their recent publications include the following papers:

  • "Therapeutic Inhibition of Acid-Sensing Ion Channel 1a Recovers Heart Function After Ischemia-Reperfusion Injury," 2021, Circulation
  • "A Bitter Taste in Your Heart," 2020, Frontiers in Physiology
  • "Modular Transient Nanoclustering of Activated β2-Adrenergic Receptors Revealed by Single-Molecule Tracking of Conformation-Specific Nanobodies," 2020, Proceedings of the National Academy of Sciences
  • "A High-Fat Diet Increases Influenza A Virus-Associated Cardiovascular Damage," 2020, The Journal of Infectious Diseases
  • "A Peptide Toxin in Ant Venom Mimics Vertebrate EGF-like Hormones to Cause Long-Lasting Hypersensitivity in Mammals," 2022, Proceedings of the National Academy of Sciences

Frequent collaborators include:

  • Melissa E. Reichelt
  • Anthony P. Davenport
  • Khuraijam Dhanachandra Singh
  • Satoru Eguchi
  • Sadashiva S. Karnik

This network of coauthors has contributed to a multidisciplinary approach that integrates molecular and cardiovascular biological sciences.

Best Publications

  • Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase

    Andrew L Carey;Gregory R Steinberg;S Lance Macaulay;Walter G Thomas

  • The renin-angiotensin system and cancer: old dog, new tricks.

    Amee J George;Walter Glen Thomas;Ross Duncan Hannan;Ross Duncan Hannan;Ross Duncan Hannan

  • High-Density Lipoprotein Modulates Glucose Metabolism in Patients With Type 2 Diabetes Mellitus

    Brian G. Drew;Stephen J. Duffy;Melissa F. Formosa;Alaina K. Natoli

  • THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors

    Stephen P.H. Alexander;Arthur Christopoulos;Anthony P. Davenport;Eamonn Kelly

  • Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest

    Richard J. Mills;Drew M. Titmarsh;Xaver Koenig;Xaver Koenig;Benjamin L. Parker

  • Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

    Alice C. Holloway;Hongwei Qian;Luisa Pipolo;James Ziogas

  • Relative affinity of angiotensin peptides and novel ligands at AT1 and AT2 receptors

    Sanja Bosnyak;Emma S. Jones;Arthur Christopoulos;Arthur Christopoulos;Marie-Isabel Aguilar

  • CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK

    Matthew James Watt;Nicolas Dzamko;Walter G Thomas;Stefan Rose-John

  • Direct Actions of Urotensin II on the Heart: Implications for Cardiac Fibrosis and Hypertrophy

    Alex Tzanidis;Ross D Hannan;Walter G Thomas;Done Onan

  • UBF levels determine the number of active ribosomal RNA genes in mammals.

    Elaine Sanij;Gretchen Poortinga;Kerith Sharkey;Sandy Hung

  • p38 mitogen-activated protein kinase inhibition improves cardiac function and attenuates left ventricular remodeling following myocardial infarction in the rat

    Fiona See;Walter Thomas;Kerrie Way;Alex Tzanidis

  • Adenoviral-Directed Expression of the Type 1A Angiotensin Receptor Promotes Cardiomyocyte Hypertrophy via Transactivation of the Epidermal Growth Factor Receptor

    Walter G. Thomas;Yves Brandenburger;Dominic J. Autelitano;Thao Pham

  • Angiotensin II stimulates sis-inducing factor-like DNA binding activity. Evidence that the AT1A receptor activates transcription factor-Stat91 and/or a related protein.

    G J Bhat;T J Thekkumkara;W G Thomas;K M Conrad

  • Effect of intrauterine growth restriction on the number of cardiomyocytes in rat hearts.

    Hugo Brandt Corstius;Monika A Zimanyi;Noori Maka;Thiloshini Herath

  • G Protein Coupling and Second Messenger Generation Are Indispensable for Metalloprotease-dependent, Heparin-binding Epidermal Growth Factor Shedding through Angiotensin II Type-1 Receptor

    Mizuo Mifune;Haruhiko Ohtsu;Hiroyuki Suzuki;Hidekatsu Nakashima

  • The Angiotensin II Type 2 Receptor Causes Constitutive Growth of Cardiomyocytes and Does Not Antagonize Angiotensin II Type 1 Receptor–Mediated Hypertrophy

    Angelo D’Amore;M. Jane Black;Walter G. Thomas

  • Expression, Regulation and Putative Nutrient-Sensing Function of Taste GPCRs in the Heart

    Simon R Foster;Enzo R Porrello;Brooke W Purdue;Hsiu Wen Chan

  • Stable expression of a truncated AT1A receptor in CHO-K1 cells. The carboxyl-terminal region directs agonist-induced internalization but not receptor signaling or desensitization.

    Walter G. Thomas;Thomas J. Thekkumkara;Thomas J. Motel;Kenneth M. Baker

  • Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular System

    Steven J Forrester;Tatsuo Kawai;Shannon O'Brien;Walter Thomas

  • Caveolin Interacts with the Angiotensin II Type 1 Receptor during Exocytic Transport but Not at the Plasma Membrane

    Bruce D. Wyse;Ian A. Prior;Hongwei Qian;Isabel C. Morrow

Frequent Co-Authors

Ross D. Hannan
Ross D. Hannan Australian National University
Andrew M. Allen
Andrew M. Allen University of Melbourne
Marie-Isabel Aguilar
Marie-Isabel Aguilar Monash University
Peter J. Little
Peter J. Little University of the Sunshine Coast
Peter S. Macdonald
Peter S. Macdonald Victor Chang Cardiac Research Institute
Henry Krum
Henry Krum Monash University
Peter C. M. Molenaar
Peter C. M. Molenaar Pennsylvania State University
Robert G. Parton
Robert G. Parton University of Queensland
Bruce E. Kemp
Bruce E. Kemp Australian Catholic University
Ross A. D. Bathgate
Ross A. D. Bathgate Florey Institute of Neuroscience and Mental Health

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