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Christopher C.W. Hughes

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
23157
World Ranking
6184
National Ranking
2910

Christopher C.W. Hughes publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Christopher C.W. Hughes sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 195 publications — 47th percentile

47% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Christopher C.W. Hughes D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Christopher C.W. Hughes sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 72 D-Index — 69th percentile

69% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Christopher C.W. Hughes is affiliated with the University of California, Irvine in the United States. Their research spans several interconnected fields including Medicine and Biochemistry, Genetics and Molecular Biology, with a focus on subfields such as Molecular Biology, Biomedical Engineering, Oncology, Surgery, and Cancer Research.

The scientist's main topics of work encompass areas related to biomedical innovation and cancer biology. These include:

  • 3D Printing in Biomedical Research
  • Cancer Cells and Metastasis
  • Angiogenesis and VEGF in Cancer
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Pancreatic function and diabetes
  • Diabetes and associated disorders
  • Cancer Genomics and Diagnostics

Christopher C.W. Hughes has contributed to several peer-reviewed papers, some of which have been cited extensively. Representative recent publications include:

  • Engineering Vascularized Organoid-on-a-Chip Models, 2021, Annual Review of Biomedical Engineering
  • An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy, 2021, Lab on a Chip
  • Tumor-on-chip modeling of organ-specific cancer and metastasis, 2021, Advanced Drug Delivery Reviews
  • Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis, 2020, Nature Communications
  • Regulation of Partial and Reversible Endothelial-to-Mesenchymal Transition in Angiogenesis, 2021, Frontiers in Cell and Developmental Biology

Frequent co-authors in Christopher C.W. Hughes's publications include:

  • Stephanie J. Hachey
  • Christopher J. Hatch
  • Steven C. George
  • Jennifer S. Fang
  • Abraham P. Lee

The scientist has published in multiple venues, with higher concentrations of work appearing in the following journals:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Lab on a Chip
  • Cell Reports
  • Frontiers in Cell and Developmental Biology
  • Annals of Surgical Oncology

Best Publications

  • Of mice and not men: differences between mouse and human immunology

    Javier Mestas;Christopher C. W. Hughes

  • Consensus guidelines for the use and interpretation of angiogenesis assays

    Patrycja Nowak-Sliwinska;Kari Alitalo;Elizabeth Allen;Andrey Anisimov

  • CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

    Karin Karmann;Christopher C. W. Hughes;Jeffrey Schechner;William C. Fanslow

  • Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1.

    Martin N. Nakatsu;Richard C.A. Sainson;Jason N. Aoto;Kevin L. Taylor

  • A conserved mechanism for steroid receptor translocation to the plasma membrane.

    Ali Pedram;Mahnaz Razandi;Richard C.A. Sainson;Jin K. Kim

  • The requirement for fibroblasts in angiogenesis: fibroblast-derived matrix proteins are essential for endothelial cell lumen formation.

    Andrew C. Newman;Martin N. Nakatsu;Wayne Chou;Paul D. Gershon

  • In Vitro Perfused Human Capillary Networks

    Monica L. Moya;Yu-Hsiang Hsu;Abraham P. Lee;Christopher C.W. Hughes

  • Diffusion limits of an in vitro thick prevascularized tissue.

    Craig K. Griffith;Cheryl Miller;Richard C.A. Sainson;Jay W. Calvert

  • Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells.

    R. N. Salomon;C. C. Hughes;F. J. Schoen;D. D. Payne

  • Wnt Signaling Induces Matrix Metalloproteinase Expression and Regulates T Cell Transmigration

    Beibei Wu;Steve P. Crampton;Christopher C.W. Hughes

  • In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse.

    J. S. Schechner;A. K. Nath;L. Zheng;M. S. Kluger

  • Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier

    N. J. Abbott;C. C. W. Hughes;P. A. Revest;J. Greenwood

  • 3D microtumors in vitro supported by perfused vascular networks

    Agua Sobrino;Duc T. T. Phan;Rupsa Datta;Xiaolin Wang

  • B7-H1 Is Expressed by Human Endothelial Cells and Suppresses T Cell Cytokine Synthesis

    Melissa M. Mazanet;Christopher C. W. Hughes

  • Prevascularization of a fibrin-based tissue construct accelerates the formation of functional anastomosis with host vasculature.

    Xiaofang Chen;Anna S. Aledia;Cyrus M. Ghajar;Craig K. Griffith

  • Crosstalk Between Vascular Endothelial Growth Factor, Notch, and Transforming Growth Factor-β in Vascular Morphogenesis

    Matthew T. Holderfield;Christopher C.W. Hughes

  • TNF primes endothelial cells for angiogenic sprouting by inducing a tip cell phenotype.

    Richard C. A. Sainson;Douglas A. Johnston;Henry C. Chu;Matthew T. Holderfield

  • Integration of the Non-genomic and Genomic Actions of Estrogen: MEMBRANE-INITIATED SIGNALING BY STEROID TO TRANSCRIPTION AND CELL BIOLOGY *

    Ali Pedram;Mahnaz Razandi;Mark Aitkenhead;Mark Aitkenhead;Christopher C.W. Hughes;Christopher C.W. Hughes

  • An optimized three-dimensional in vitro model for the analysis of angiogenesis.

    Martin N. Nakatsu;Christopher C.W. Hughes

  • The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis

    Cyrus M. Ghajar;Xiaofang Chen;Joseph W. Harris;Vinod Suresh

Frequent Co-Authors

Abraham P. Lee
Abraham P. Lee University of California, Irvine
Jordan S. Pober
Jordan S. Pober Yale University
Marian L. Waterman
Marian L. Waterman University of California, Irvine
Rolf A. Brekken
Rolf A. Brekken The University of Texas Southwestern Medical Center
John Lowengrub
John Lowengrub University of California, Irvine
Steven Z. George
Steven Z. George Duke University
Philip W. Askenase
Philip W. Askenase Yale University
Noo Li Jeon
Noo Li Jeon Seoul National University
Andrew J. Putnam
Andrew J. Putnam University of Michigan–Ann Arbor
Gaetan Lesca
Gaetan Lesca Claude Bernard University Lyon 1

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Best Scientists Citing Christopher C.W. Hughes

Jordan S. Pober

Jordan S. Pober

Yale University

Publications: 103

Roger D. Kamm

Roger D. Kamm

MIT

Publications: 55

Andrew J. Putnam

Andrew J. Putnam

University of Michigan–Ann Arbor

Publications: 49

Ellis R. Levin

Ellis R. Levin

University of California, Irvine

Publications: 40

Lieping Chen

Lieping Chen

Yale University

Publications: 30

Bert A. 't Hart

Bert A. 't Hart

University of Amsterdam

Publications: 30

George E. Davis

George E. Davis

University of South Florida

Publications: 30

Richard A. Flavell

Richard A. Flavell

Yale University

Publications: 29

Jan Kitajewski

Jan Kitajewski

Columbia University

Publications: 29

John Greenwood

John Greenwood

University College London

Publications: 28

David J. Mooney

David J. Mooney

Harvard University

Publications: 27

Christopher S. Chen

Christopher S. Chen

Boston University

Publications: 26

Peter Libby

Peter Libby

Brigham and Women's Hospital

Publications: 25

Ali Khademhosseini

Ali Khademhosseini

Terasaki Foundation

Publications: 25

Jacques Banchereau

Jacques Banchereau

Immunai

Publications: 24

Domenico Ribatti

Domenico Ribatti

University of Bari Aldo Moro

Publications: 23

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