D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 58 Citations 16,708 100 World Ranking 6178 National Ranking 2892

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Cancer
  • Immune system

Christopher C.W. Hughes focuses on Cell biology, Angiogenesis, Molecular biology, Endothelial stem cell and Immunology. His Cell biology research is multidisciplinary, incorporating perspectives in Tumor necrosis factor alpha, T cell and Cytotoxic T cell. His Angiogenesis research focuses on Endocrinology and how it relates to Tube morphogenesis.

His research in Molecular biology intersects with topics in Interleukin, Fibroblast and Extracellular matrix. His Endothelial stem cell research includes themes of Growth factor and Notch signaling pathway. Christopher C.W. Hughes has researched Immunology in several fields, including Coronary arteries and Endothelium.

His most cited work include:

  • Of mice and not men: differences between mouse and human immunology (2264 citations)
  • CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression. (421 citations)
  • Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1. (377 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Angiogenesis, Cancer research, Immunology and Molecular biology. His Cell biology research integrates issues from Endocrinology, In vitro and Internal medicine. The study incorporates disciplines such as Endothelial stem cell, Tube formation, Blood vessel, Basement membrane and Extracellular matrix in addition to Angiogenesis.

His research investigates the connection between Cancer research and topics such as Pathology that intersect with problems in Transplantation. His study ties his expertise on Endothelium together with the subject of Immunology. In his research on the topic of Molecular biology, Cytokine is strongly related with Tumor necrosis factor alpha.

He most often published in these fields:

  • Cell biology (31.61%)
  • Angiogenesis (27.59%)
  • Cancer research (21.84%)

What were the highlights of his more recent work (between 2017-2021)?

  • Cancer research (21.84%)
  • In vivo (13.79%)
  • Internal medicine (9.20%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cancer research, In vivo, Internal medicine, Angiogenesis and Prostate cancer. His Cancer research study combines topics from a wide range of disciplines, such as Tumor necrosis factor alpha, Cancer, CDC42, GTPase and Response to therapy. His work in In vivo tackles topics such as Drug which are related to areas like In vitro and Disease.

Christopher C.W. Hughes has included themes like Endothelial stem cell, Vasculogenesis, Extravasation and Cell biology in his Angiogenesis study. His Endothelial stem cell study integrates concerns from other disciplines, such as Function, Signal transduction, Notch signaling pathway, Slug and Organ-on-a-chip. His Cell biology study frequently draws parallels with other fields, such as Tube formation.

Between 2017 and 2021, his most popular works were:

  • Consensus guidelines for the use and interpretation of angiogenesis assays (194 citations)
  • Applications of tumor chip technology (34 citations)
  • Pazopanib may reduce bleeding in hereditary hemorrhagic telangiectasia. (33 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Cancer
  • Immune system

Angiogenesis, In vivo, Tumor cells, Vasculogenesis and Extravasation are his primary areas of study. His studies deal with areas such as Tumor angiogenesis and Computational biology as well as Angiogenesis. He integrates In vivo and Preclinical research in his research.

Many of his studies on Tumor cells involve topics that are commonly interrelated, such as Neuroscience.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Of mice and not men: differences between mouse and human immunology

Javier Mestas;Christopher C. W. Hughes.
Journal of Immunology (2004)

3074 Citations

CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.

Karin Karmann;Christopher C. W. Hughes;Jeffrey Schechner;William C. Fanslow.
Proceedings of the National Academy of Sciences of the United States of America (1995)

569 Citations

A conserved mechanism for steroid receptor translocation to the plasma membrane.

Ali Pedram;Mahnaz Razandi;Richard C.A. Sainson;Jin K. Kim.
Journal of Biological Chemistry (2007)

472 Citations

Angiogenic sprouting and capillary lumen formation modeled by human umbilical vein endothelial cells (HUVEC) in fibrin gels: the role of fibroblasts and Angiopoietin-1.

Martin N. Nakatsu;Richard C.A. Sainson;Jason N. Aoto;Kevin L. Taylor.
Microvascular Research (2003)

472 Citations

Human coronary transplantation-associated arteriosclerosis. Evidence for a chronic immune reaction to activated graft endothelial cells.

R. N. Salomon;C. C. Hughes;F. J. Schoen;D. D. Payne.
American Journal of Pathology (1991)

425 Citations

Diffusion limits of an in vitro thick prevascularized tissue.

Craig K. Griffith;Cheryl Miller;Richard C.A. Sainson;Jay W. Calvert.
Tissue Engineering (2005)

394 Citations

In vivo formation of complex microvessels lined by human endothelial cells in an immunodeficient mouse.

J. S. Schechner;A. K. Nath;L. Zheng;M. S. Kluger.
Proceedings of the National Academy of Sciences of the United States of America (2000)

390 Citations

Development and characterisation of a rat brain capillary endothelial culture: towards an in vitro blood-brain barrier

N. J. Abbott;C. C. W. Hughes;P. A. Revest;J. Greenwood.
Journal of Cell Science (1992)

376 Citations

Wnt Signaling Induces Matrix Metalloproteinase Expression and Regulates T Cell Transmigration

Beibei Wu;Steve P. Crampton;Christopher C.W. Hughes.
Immunity (2007)

363 Citations

Integration of the Non-genomic and Genomic Actions of Estrogen: MEMBRANE-INITIATED SIGNALING BY STEROID TO TRANSCRIPTION AND CELL BIOLOGY *

Ali Pedram;Mahnaz Razandi;Mark Aitkenhead;Mark Aitkenhead;Christopher C.W. Hughes;Christopher C.W. Hughes.
Journal of Biological Chemistry (2002)

355 Citations

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