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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
11771
World Ranking
14983
National Ranking
6268

Overview

Marian L. Waterman is affiliated with the University of California, Irvine in the United States. Their research primarily focuses on Biochemistry, Genetics, and Molecular Biology, with a significant emphasis on Molecular Biology, Oncology, Biomedical Engineering, Cancer Research, and Genetics as subfields.

The scientist's main topics of work include:

  • Cancer Cells and Metastasis
  • Single-cell and spatial transcriptomics
  • 3D Printing in Biomedical Research
  • Cancer, Hypoxia, and Metabolism
  • Advanced Biosensing Techniques and Applications
  • Cancer Genomics and Diagnostics
  • Hedgehog Signaling Pathway Studies

Marian L. Waterman has contributed to several prominent publication venues, with multiple papers appearing in the following journals:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Communications Biology
  • Nature Cancer
  • Lab on a Chip
  • Science Advances

Their recent papers include the following:

  • "α-Ketoglutarate attenuates Wnt signaling and drives differentiation in colorectal cancer," 2020, Nature Cancer
  • "An in vitro vascularized micro-tumor model of human colorectal cancer recapitulates in vivo responses to standard-of-care therapy," 2021, Lab on a Chip
  • "Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer," 2022, Science Advances
  • "Spatial transcriptomics using combinatorial fluorescence spectral and lifetime encoding, imaging and analysis," 2022, Nature Communications
  • "Transcriptomic and proteomic signatures of stemness and differentiation in the colon crypt," 2020, Communications Biology

Frequent co-authors collaborating with Waterman include:

  • Amber N. Habowski
  • Robert A. Edwards
  • Jie Wu
  • Anand K. Ganesan
  • Linzi Hosohama

Best Publications

  • The TAK1–NLK–MAPK-related pathway antagonizes signalling between β-catenin and transcription factor TCF

    Tohru Ishitani;Jun Ninomiya-Tsuji;Shln Ichl Nagai;Michiru Nishita

  • TCF/LEFs and Wnt Signaling in the Nucleus

    Ken M. Cadigan;Marian L. Waterman

  • The TAK1-NLK Mitogen-Activated Protein Kinase Cascade Functions in the Wnt-5a/Ca2+ Pathway To Antagonize Wnt/β-Catenin Signaling

    Tohru Ishitani;Satoshi Kishida;Junko Hyodo-Miura;Junko Hyodo-Miura;Naoto Ueno

  • Beta-catenin-sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer.

    Karine Hovanes;Tony W.H. Li;Jesus E. Munguia;Trung Truong

  • Diversity of LEF/TCF action in development and disease

    L Arce;N N Yokoyama;M L Waterman

  • A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer.

    M L Waterman;W H Fischer;K A Jones

  • Wnt signaling directs a metabolic program of glycolysis and angiogenesis in colon cancer

    Kira T Pate;Chiara Stringari;Stephanie Sprowl-Tanio;Kehui Wang

  • NOTCH signaling is required for formation and self-renewal of tumor-initiating cells and for repression of secretory cell differentiation in colon cancer.

    Shaheen S Sikandar;Kira T Pate;Scott Anderson;Diana Dizon

  • Metabolic trajectory of cellular differentiation in small intestine by Phasor Fluorescence Lifetime Microscopy of NADH

    Chiara Stringari;Robert A. Edwards;Kira T. Pate;Marian L. Waterman

  • Steroid receptor-mediated inhibition of rat prolactin gene expression does not require the receptor DNA-binding domain

    Stuart Adler;Marian L. Waterman;Xi He;Michael G. Rosenfeld

  • T cell factor 1 initiates the T helper type 2 fate by inducing the transcription factor GATA-3 and repressing interferon-gamma.

    Qing Yu;Archna Sharma;Sun Young Oh;Hyung Geun Moon

  • Expression of Wnt ligands and Frizzled receptors in colonic mucosa and in colon carcinoma.

    R F Holcombe;J L Marsh;M L Waterman;F Lin

  • Wnt signaling and colon carcinogenesis: beyond APC.

    Rani Najdi;Randall F Holcombe;Marian L Waterman

  • A single domain of the estrogen receptor confers deoxyribonucleic acid binding and transcriptional activation of the rat prolactin gene

    Marian L. Waterman;Stuart Adlerf;Christian Nelson;Geoffrey L. Greene

  • The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells.

    Peter Carlsson;Marian L. Waterman;Katherine A. Jones

  • A three-dimensional in vitro model of tumor cell intravasation

    Seema M. Ehsan;Katrina M. Welch-Reardon;Marian L. Waterman;Christopher C. W. Hughes

  • Induction of a β-catenin-LEF-1 complex by wnt-1 and transforming mutants of β-catenin

    Emilio Porfiri;Bonnee Rubinfeld;Iris Albert;Karine Hovanes

  • Purification of TCF-1 alpha, a T-cell-specific transcription factor that activates the T-cell receptor C alpha gene enhancer in a context-dependent manner.

    M L Waterman;K A Jones

  • A Unique DNA Binding Domain Converts T-Cell Factors into Strong Wnt Effectors

    Fawzia A. Atcha;Adeela Syed;Beibei Wu;Nate P. Hoverter

  • A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities

    Rani Najdi;Kyle Proffitt;Stephanie Sprowl;Simran Kaur

Frequent Co-Authors

Christopher C.W. Hughes
Christopher C.W. Hughes University of California, Irvine
John Lowengrub
John Lowengrub University of California, Irvine
Michael G. Rosenfeld
Michael G. Rosenfeld University of California, San Diego
J. Lawrence Marsh
J. Lawrence Marsh University of California, Irvine
Ronald M. Evans
Ronald M. Evans Salk Institute for Biological Studies
Katherine A. Jones
Katherine A. Jones Salk Institute for Biological Studies
Bert L. Semler
Bert L. Semler University of California, Irvine
Enrico Gratton
Enrico Gratton University of California, Irvine
Arthur D. Lander
Arthur D. Lander University of California, Irvine
David M. Virshup
David M. Virshup Duke NUS Graduate Medical School

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