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Philip W. Askenase

Philip W. Askenase

D-Index & Metrics

Immunology

D-Index
73
Citations
19090
World Ranking
2141
National Ranking
1042

Overview

Philip W. Askenase is affiliated with Yale University in the United States and conducts research primarily in the fields of medicine and biochemistry, genetics, and molecular biology. Their work spans multiple subfields, including molecular biology, dermatology, pathology and forensic medicine, infectious diseases, and cancer research.

The primary topics covered in their research involve extracellular vesicles in disease, spinal cord injury research, COVID-19 clinical research studies, microRNA in disease regulation, mesenchymal stem cell research, dermatological and COVID-19 studies, and circular RNAs in diseases.

The scientist has contributed to several recent papers, including the following:

  • Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF-β upregulation, microvascular stabilization and functional recovery in a rodent model of severe spinal cord injury (2021, Journal of Extracellular Vesicles)
  • COVID-19 therapy with mesenchymal stromal cells (MSC) and convalescent plasma must consider exosome involvement: Do the exosomes in convalescent plasma antagonize the weak immune antibodies? (2020, Journal of Extracellular Vesicles)
  • Exosomes provide unappreciated carrier effects that assist transfers of their miRNAs to targeted cells; I. They are 'The Elephant in the Room' (2021, RNA Biology)
  • Rare Skin Reactions after mRNA Vaccination, Similar to Jones-Mote Basophil Responses (2021, New England Journal of Medicine)
  • Recommendation: Treatment of clinical long COVID encephalopathies with nasal administered mesenchymal stromal cell extracellular vesicles (2022, Frontiers in Nanotechnology)

Frequent coauthors associated with their publications include Masahito Nakazaki, Tomonori Morita, Karen L. Lankford, Jeffery D. Kocsis, and Monika Majewska-Szczepanik.

Their work has appeared multiple times in key publication venues, notably:

  • Journal of Extracellular Vesicles (2 publications)
  • RNA Biology (1 publication)
  • New England Journal of Medicine (1 publication)
  • Frontiers in Nanotechnology (1 publication)
  • Contact Dermatitis (1 publication)

Best Publications

  • Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

    Hina Kalra;Richard J. Simpson;Hong Ji;Elena Aikawa

  • Critical role for NALP3/CIAS1/cryopyrin in innate and adaptive immunity through its regulation of caspase-1

    Fayyaz S. Sutterwala;Yasunori Ogura;Marian Szczepanik;Marian Szczepanik;Maria Lara-Tejero

  • Development of atopic dermatitis-like skin lesion with IgE hyperproduction in NC/Nga mice.

    H Matsuda;N Watanabe;G P Geba;J Sperl

  • Critical role for the chemokine receptor CXCR6 in NK cell-mediated antigen-specific memory of haptens and viruses

    Silke Paust;Silke Paust;Harvinder S Gill;Harvinder S Gill;Bao-Zhong Wang;Michael P Flynn

  • Augmentation of delayed-type hypersensitivity by doses of cyclophosphamide which do not affect antibody responses.

    P W Askenase;B J Hayden;R K Gershon

  • Cutting Edge: Invariant Vα14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model

    Mariette Lisbonne;Séverine Diem;Alexandre de Castro Keller;Alexandre de Castro Keller;Jean Lefort

  • Salp15, an Ixodes scapularis Salivary Protein, Inhibits CD4+ T Cell Activation

    Juan Anguita;Nandhini Ramamoorthi;Joppe W.R Hovius;Subrata Das

  • A novel community driven software for functional enrichment analysis of extracellular vesicles data

    Mohashin Pathan;Shivakumar Keerthikumar;David Chisanga;Riccardo Alessandro

  • Differential release of serotonin and histamine from mast cells

    Theoharis C. Theoharides;Philip K. Bondy;Nikolaos D. Tsakalos;Philip W. Askenase

  • Lyme arthritis. Spirochetes found in synovial microangiopathic lesions.

    Y. E. Johnston;P. H. Duray;A. C. Steere;M. Kashgarian

  • Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity

    Krzysztof Bryniarski;Wlodzimierz Ptak;Asha Jayakumar;Kerstin Püllmann

  • Role of antigen-presenting cells in the development and persistence of contact hypersensitivity.

    W Ptak;D Rozycka;P W Askenase;R K Gershon

  • Intravenously delivered mesenchymal stem cell-derived exosomes target M2-type macrophages in the injured spinal cord.

    Karen L. Lankford;Edgardo J. Arroyo;Katarzyna Nazimek;Krzysztof Bryniarski;Krzysztof Bryniarski

  • Cutaneous Immunization Rapidly Activates Liver Invariant Vα14 NKT Cells Stimulating B-1 B Cells to Initiate T Cell Recruitment for Elicitation of Contact Sensitivity

    Regis A. Campos;Marian Szczepanik;Atsuko Itakura;Moe Akahira-Azuma

  • Ablation of immunity to Amblyomma americanum by anti-basophil serum: cooperation between basophils and eosinophils in expression of immunity to ectoparasites (ticks) in guinea pigs.

    S J Brown;S J Galli;G J Gleich;P W Askenase

  • Requirement for vasoactive amines for production of delayed-type hypersensitvity skin reactions.

    Richard K. Gershon;Philip W. Askenase;Michael D. Gershon

  • T cell-dependent mast cell degranulation and release of serotonin in murine delayed-type hypersensitivity.

    P W Askenase;S Bursztajn;M D Gershon;R K Gershon

  • IgE-dependent release of leukotriene C4 from alveolar macrophages.

    John A. Rankin;Margaret Hitchcock;William Merrill;Michael K. Bach

  • An early component of delayed-type hypersensitivity mediated by T cells and mast cells.

    H van Loveren;R Meade;P W Askenase

  • Role of Basophils, Mast Cells, and Vasoamines in Hypersensitivity Reactions with a Delayed Time Course (Part 1 of 4)

    Unknown

  • Molecular mechanisms of CD8+ T cell–mediated delayed hypersensitivity: Implications for allergies, asthma, and autoimmunity

    Richard S. Kalish;Philip W. Askenase

  • Delayed-type hypersensitivity: activation of mast cells by antigen-specific T-cell factors initiates the cascade of cellular interactions

    Philip W Askenase;Henk Van Loverent

Frequent Co-Authors

Richard K. Gershon
Richard K. Gershon Yale University
Stephen J. Brown
Stephen J. Brown New York University
Theoharis C. Theoharides
Theoharis C. Theoharides Nova Southeastern University
Hiroshi Matsuda
Hiroshi Matsuda Tokyo University of Agriculture and Technology
Jordan S. Pober
Jordan S. Pober Yale University
Frank A. Redegeld
Frank A. Redegeld Utrecht University
Maria C. Leite-de-Moraes
Maria C. Leite-de-Moraes Centre national de la recherche scientifique, CNRS
Michael Kashgarian
Michael Kashgarian Yale University
Martin K. Church
Martin K. Church Southampton General Hospital
Jun Lu
Jun Lu Zhejiang University

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Related Online Degrees & Career Pathways

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Choosing the right online degree or certification program is vital for those balancing career goals with academic progression, particularly in complex fields like immunology intertwined with nursing and healthcare.

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