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Immunology

D-Index
45
Citations
7446
World Ranking
4709
National Ranking
224

Overview

Maria C. Leite-de-Moraes is affiliated with the Centre national de la recherche scientifique (CNRS) in France. Their research spans multiple domains within medicine and immunology, focusing on cellular and molecular mechanisms relevant to immune responses and respiratory diseases.

The scientist's work includes 31 publications in the field of medicine and 18 in immunology and microbiology. Subfields of study emphasize immunology, physiology, molecular biology, infectious diseases, and pulmonary and respiratory medicine.

Key research topics addressed by Maria C. Leite-de-Moraes include:

  • IL-33, ST2, and ILC pathways
  • Asthma and respiratory diseases
  • Immune cell function and interaction
  • T-cell and B-cell immunology
  • Antimicrobial resistance in Staphylococcus
  • Allergic rhinitis and sensitization
  • Dermatology and skin diseases

The scientist has published frequently in several journals, including:

  • Frontiers in Immunology
  • Science Translational Medicine
  • Allergy
  • Cell Reports
  • JCI Insight

Notable recent publications span from 2020 to 2023 and include:

  • "High Dimensional Single-Cell Analysis Reveals iNKT Cell Developmental Trajectories and Effector Fate Decision," 2020, Cell Reports
  • "Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation," 2020, JCI Insight
  • "New Insights into Asthma Inflammation: Focus on iNKT, MAIT, and γδT Cells," 2020, Clinical Reviews in Allergy & Immunology
  • "Assessment of local and systemic signature of eosinophilic esophagitis (EoE) in children through multi-omics approaches," 2023, Frontiers in Immunology
  • "A Comprehensive Analysis of Immune Constituents in Blood and Bronchoalveolar Lavage Allows Identification of an Immune Signature of Severe Asthma in Children," 2021, Frontiers in Immunology

Maria C. Leite-de-Moraes has collaborated with several researchers on multiple occasions, including:

  • Céline Dietrich
  • Guillaume Lezmi
  • Karine Adel-Patient
  • Marta Grauso
  • Blanche Guillon

Best Publications

  • Activation of natural killer T cells by α -galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes

    Shayan Sharif;Guillermo A. Arreaza;Peter Zucker;Qing-Sheng Mi

  • Identification of an IL-17–producing NK1.1neg iNKT cell population involved in airway neutrophilia

    Marie-Laure Michel;Alexandre Castro Keller;Christophe Paget;Christophe Paget;Masakazu Fujio

  • Cutting Edge: Invariant Vα14 NKT Cells Are Required for Allergen-Induced Airway Inflammation and Hyperreactivity in an Experimental Asthma Model

    Mariette Lisbonne;Séverine Diem;Alexandre de Castro Keller;Alexandre de Castro Keller;Jean Lefort

  • Activation of Invariant NKT Cells by Toll-like Receptor 9-Stimulated Dendritic Cells Requires Type I Interferon and Charged Glycosphingolipids

    Christophe Paget;Christophe Paget;Thierry Mallevaey;Thierry Mallevaey;Anneliese O. Speak;David Torres;David Torres

  • Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation

    Marie-Laure Michel;Daniella Mendes-da-Cruz;Alexandre Castro Keller;Matthias Lochner

  • A distinct IL-18-induced pathway to fully activate NK T lymphocytes independently from TCR engagement.

    Maria C. Leite-de-Moraes;Agathe Hameg;Anne Arnould;François Machavoine

  • IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis.

    Paméla Gasse;Nicolas Riteau;Rachel Vacher;Marie-Laure Michel

  • Relevance of sexual dimorphism to regulatory T cells: estradiol promotes IFN-γ production by invariant natural killer T cells

    Pierre Gourdy;Luiza M. Araujo;Ren Zhu;Barbara Garmy-Susini

  • IL-18 Enhances IL-4 Production by Ligand-Activated NKT Lymphocytes: A Pro-Th2 Effect of IL-18 Exerted Through NKT Cells

    Maria C. Leite-de-Moraes;Agathe Hameg;Maria Pacilio;Yasuhiko Koezuka

  • α‐Galactosylceramide‐induced iNKT cells suppress experimental allergic asthma in sensitized mice: Role of IFN‐γ

    Patricia Hachem;Mariette Lisbonne;Marie-Laure Michel;Séverine Diem

  • Fas/Fas Ligand Interactions Promote Activation-Induced Cell Death of NK T Lymphocytes

    Maria C. Leite-de-Moraes;André Herbelin;Christine Gouarin;Yasuhiko Koezuka

  • The Ets-1 transcription factor controls the development and function of natural regulatory T cells.

    Enguerran Mouly;Karine Chemin;Hai Vu Nguyen;Martine Chopin

  • Early posttransplantation donor-derived invariant natural killer T-cell recovery predicts the occurrence of acute graft-versus-host disease and overall survival.

    Marie-Thérèse Rubio;Lucia Moreira-Teixeira;Emmanuel Bachy;Marie Bouillié

  • IL-4-producing NK T cells are biased towards IFN-γ production by IL-12. Influence of the microenvironment on the functional capacities of NK T cells

    Maria C. Leite-De-Moraes;Géraldine Moreau;Anne Arnould;François Machavoine

  • Invariant natural killer T cells in bronchial asthma.

    Seddon Y Thomas;Craig M Lilly;Andrew D Luster

  • NKT cells are critical for the initiation of an inflammatory bowel response against Toxoplasma gondii

    Catherine Ronet;Sylvie Darche;Maria Leite de Moraes;Sachiko Miyake

  • Studies on the thymus in chagas' disease

    Wilson Savino;Maria Do Carmo Leite-de-Moraes;Mireille Hontebeyrie-Joskowicz;Mireille Dardenne

  • Activation of Invariant NKT Cells by the Helminth Parasite Schistosoma mansoni

    Thierry Mallevaey;Jean Pierre Zanetta;Christelle Faveeuw;Christelle Faveeuw;Christelle Faveeuw;Josette Fontaine;Josette Fontaine;Josette Fontaine

  • Proinflammatory Environment Dictates the IL-17–Producing Capacity of Human Invariant NKT Cells

    Lúcia Moreira-Teixeira;Mariana Resende;Maryaline Coffre;Odile Devergne

  • Enhanced frequency of immunoregulatory invariant natural killer T cells in the airways of children with asthma.

    Nhan Pham-Thi;Jacques de Blic;Muriel Le Bourgeois;Michel Dy

Frequent Co-Authors

Michel Dy
Michel Dy Université Paris Cité
Olivier Hermine
Olivier Hermine Necker-Enfants Malades Hospital
François Trottein
François Trottein Institut Pasteur
Yasuhiko Koezuka
Yasuhiko Koezuka Vanderbilt University
Agnès Lehuen
Agnès Lehuen Université Paris Cité
Stefan H. E. Kaufmann
Stefan H. E. Kaufmann Max Planck Institute for Infection Biology
Gérard Eberl
Gérard Eberl Université Paris Cité
Philip W. Askenase
Philip W. Askenase Yale University
Mustapha Si-Tahar
Mustapha Si-Tahar François Rabelais University

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