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François Trottein

François Trottein

D-Index & Metrics

Immunology

D-Index
68
Citations
15300
World Ranking
2606
National Ranking
111

Overview

François Trottein is a researcher affiliated with the Institut Pasteur in France, with a primary focus on medicine, immunology, and microbiology. Their work spans a range of subfields including immunology, infectious diseases, molecular biology, physiology, and epidemiology. The scientist's research addresses several interconnected topics, notably gut microbiota and health, Clostridium difficile and Clostridium perfringens research, COVID-19 clinical research studies, SARS-CoV-2 and COVID-19 research, immune cell function and interaction, diet and metabolism studies, and immune cells in cancer.

The scientist has contributed to numerous papers, some of which have been published in prominent journals. Selected recent publications include:

  • Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production, 2020, Cell Reports
  • The lung-gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes, 2021, Mucosal Immunology
  • A druggable copper-signalling pathway that drives inflammation, 2023, Nature
  • The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells, 2021, Nature Neuroscience
  • Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells, 2021, Cell Reports

The scientist frequently collaborates with other researchers, including Valentin Sencio, Cyril Robil, Séverine Heumel, Arnaud Machelart, and Isabelle Wolowczuk. The extent of collaboration varies, with Valentin Sencio being the most frequent co-author.

François Trottein's work has been published in several venues that reflect their research focus. These include bioRxiv (Cold Spring Harbor Laboratory), Gut Microbes, Cell Reports, Zenodo (CERN European Organization for Nuclear Research), and Frontiers in Immunology.

Best Publications

  • Peroxisome proliferator-activated receptor activators inhibit thrombin-induced endothelin-1 production in human vascular endothelial cells by inhibiting the activator protein-1 signaling pathway

    Philippe Delerive;Françoise Martin-Nizard;Giulia Chinetti;François Trottein

  • Identification of an IL-17–producing NK1.1neg iNKT cell population involved in airway neutrophilia

    Marie-Laure Michel;Alexandre Castro Keller;Christophe Paget;Christophe Paget;Masakazu Fujio

  • Immunoreactivity in mammals of two typical plant glyco-epitopes, core α(1,3)-fucose and core xylose

    Muriel Bardor;Christelle Faveeuw;Anne-Catherine Fitchette;Danièle Gilbert

  • Role of the Parasite-Derived Prostaglandin D2 in the Inhibition of Epidermal Langerhans Cell Migration during Schistosomiasis Infection

    Véronique Angeli;Christelle Faveeuw;Olivier Roye;Josette Fontaine

  • The orphan nuclear receptor RORα is a negative regulator of the inflammatory response

    Philippe Delerive;Didier Monté;Guillaume Dubois;François Trottein

  • Peroxisome proliferator‐activated receptor γ activators affect the maturation of human monocyte‐derived dendritic cells

    Philippe Gosset;Anne-Sophie Charbonnier;Philippe Delerive;Josette Fontaine

  • The role of PPARs in atherosclerosis

    Caroline Duval;Giulia Chinetti;Francois Trottein;Jean-Charles Fruchart

  • Gut Dysbiosis during Influenza Contributes to Pulmonary Pneumococcal Superinfection through Altered Short-Chain Fatty Acid Production

    Valentin Sencio;Adeline Barthelemy;Luciana P. Tavares;Marina G. Machado

  • Activation of Invariant NKT Cells by Toll-like Receptor 9-Stimulated Dendritic Cells Requires Type I Interferon and Charged Glycosphingolipids

    Christophe Paget;Christophe Paget;Thierry Mallevaey;Thierry Mallevaey;Anneliese O. Speak;David Torres;David Torres

  • Specific Recognition of Candida albicans by Macrophages Requires Galectin-3 to Discriminate Saccharomyces cerevisiae and Needs Association with TLR2 for Signaling

    Thierry Jouault;Miryam El Abed-El Behi;María Martínez-Esparza;Laetitia Breuilh

  • The lung-gut axis during viral respiratory infections: the impact of gut dysbiosis on secondary disease outcomes.

    Valentin Sencio;Marina Gomes Machado;François Trottein

  • Activation of the D prostanoid 1 receptor suppresses asthma by modulation of lung dendritic cell function and induction of regulatory T cells

    Hamida Hammad;Mirjam Kool;Thomas Soullié;Shuh Narumiya

  • Activation of the Prostaglandin D2 Receptor DP2/CRTH2 Increases Allergic Inflammation in Mouse

    Isabelle Spik;Céline Brénuchon;Véronique Angéli;Delphine Staumont

  • Prostaglandin D2 Inhibits Airway Dendritic Cell Migration and Function in Steady State Conditions by Selective Activation of the D Prostanoid Receptor 1

    Hamida Hammad;Hendrik Jan de Heer;Thomas Soullie;Henk C. Hoogsteden

  • The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells

    Jan Wenzel;Josephine Lampe;Helge Müller-Fielitz;Raphael Schuster

  • Peroxisome proliferator-activated receptor γ activators inhibit interleukin-12 production in murine dendritic cells

    Christelle Faveeuw;Sylvie Fougeray;Véronique Angeli;Josette Fontaine

  • Activation of Peroxisome Proliferator-Activated Receptor-γ in Dendritic Cells Inhibits the Development of Eosinophilic Airway Inflammation in a Mouse Model of Asthma

    Hamida Hammad;Hendrik Jan de Heer;Thomas Soullié;Véronique Angeli

  • Gut microbiota-derived short-chain fatty acids regulate IL-17 production by mouse and human intestinal γδ T cells.

    Louise Dupraz;Louise Dupraz;Aurélie Magniez;Nathalie Rolhion;Mathias L. Richard

  • Double-stranded RNAs from the helminth parasite Schistosoma activate TLR3 in dendritic cells.

    Ezra Aksoy;Ezra Aksoy;Claudia S. Zouain;François Vanhoutte;Josette Fontaine

  • Early IL-2 Production by Mouse Dendritic Cells Is the Result of Microbial-Induced Priming

    Francesca Granucci;Sonia Feau;Sonia Feau;Véronique Angeli;François Trottein

  • Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection: POTENTIAL ROLE IN PROTECTION AGAINST LUNG EPITHELIAL DAMAGES*

    Christophe Paget;Stoyan Ivanov;Josette Fontaine;Joelle Renneson

  • Pivotal roles of the parasite PGD2 synthase and of the host D prostanoid receptor 1 in schistosome immune evasion.

    Maxime Hervé;Véronique Angeli;Elena Pinzar;René Wintjens

Frequent Co-Authors

Monique Capron
Monique Capron University of Lille
Philippe Gosset
Philippe Gosset Institut Pasteur
André Capron
André Capron Institut Pasteur
Jean-Claude Sirard
Jean-Claude Sirard Institut Pasteur
Mustapha Si-Tahar
Mustapha Si-Tahar François Rabelais University
Raymond J. Pierce
Raymond J. Pierce University of Lille
Bernhard Ryffel
Bernhard Ryffel University of Orléans
Bart Staels
Bart Staels University of Lille
André-Bernard Tonnel
André-Bernard Tonnel University of Lille
Bart N. Lambrecht
Bart N. Lambrecht Ghent University

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