World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
85
Citations
30395
World Ranking
3112
National Ranking
1574

Cynthia L. Sears publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Cynthia L. Sears sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 413 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 848 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 949 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 840 scientists 207–216 publications: 733 scientists 217–226 publications: 708 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 417 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 196 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 59 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 318 publications — 81st percentile

81% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Cynthia L. Sears D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Cynthia L. Sears sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 316 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 899 scientists 52–53 D-Index: 1,025 scientists 54–55 D-Index: 1,149 scientists 56–57 D-Index: 1,235 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,162 scientists 62–63 D-Index: 1,130 scientists 64–65 D-Index: 1,031 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 714 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 71 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 85 D-Index — 84th percentile

84% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Cynthia L. Sears is affiliated with Johns Hopkins University in the United States. Their research focuses extensively on medicine, with significant contributions in biochemistry, genetics, and molecular biology. The subfields of their work include molecular biology, oncology, epidemiology, infectious diseases, and surgery.

The scientist's main research topics cover gut microbiota and health, cancer immunotherapy and biomarkers, Clostridium difficile and Clostridium perfringens research, Mycobacterium research and diagnosis, colorectal cancer screening and detection, cancer research and treatments, as well as pancreatic and hepatic oncology research.

They have published multiple papers in well-known venues such as Gastroenterology, The Journal of Infectious Diseases, Cancer Research, bioRxiv (Cold Spring Harbor Laboratory), and Cancer Discovery. Their frequent coauthors include Julia L. Drewes, Shaoguang Wu, James R. White, Fyza Y. Shaikh, and Martha J. Shrubsole.

Notable recent papers include:

  • Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps (2021, Cell)
  • A Procarcinogenic Colon Microbe Promotes Breast Tumorigenesis and Metastatic Progression and Concomitantly Activates Notch and β-Catenin Axes (2021, Cancer Discovery)
  • Intestinal Bacteria Maintain Adult Enteric Nervous System and Nitrergic Neurons via Toll-like Receptor 2-induced Neurogenesis in Mice (2020, Gastroenterology)
  • Human Colon Cancer-Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice (2022, Cancer Discovery)
  • Prevalence and association of pks+ Escherichia coli with colorectal cancer in patients at the University Malaya Medical Centre, Malaysia (2020, PLoS ONE)

Best Publications

  • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses

    Shaoguang Wu;Ki Jong Rhee;Ki Jong Rhee;Ki Jong Rhee;Emilia Albesiano;Shervin Rabizadeh

  • The Vigorous Immune Microenvironment of Microsatellite Instable Colon Cancer Is Balanced by Multiple Counter-Inhibitory Checkpoints

    Nicolas J. Llosa;Michael Cruise;Ada Tam;Elizabeth C. Wicks

  • Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes

    Erick Riquelme;Erick Riquelme;Yu Zhang;Liangliang Zhang;Maria Montiel

  • Microbes, Microbiota, and Colon Cancer

    Cynthia L. Sears;Wendy S. Garrett

  • Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria

    Christine M. Dejea;Payam Fathi;John M. Craig;Annemarie Boleij;Annemarie Boleij

  • Microbiota organization is a distinct feature of proximal colorectal cancers

    Christine M. Dejea;Elizabeth C. Wick;Elizabeth M. Hechenbleikner;James R. White

  • Enteric bacterial toxins: mechanisms of action and linkage to intestinal secretion.

    Cynthia L. Sears;James B. Kaper

  • The emerging clinical importance of non-O157 Shiga toxin-producing Escherichia coli.

    Kristine E. Johnson;Cheleste M. Thorpe;Cynthia L. Sears

  • The Bacteroides fragilis Toxin Gene Is Prevalent in the Colon Mucosa of Colorectal Cancer Patients

    Annemarie Boleij;Elizabeth M. Hechenbleikner;Andrew C. Goodwin;Ruchi Badani

  • Oxidative Damage Targets Complexes Containing DNA Methyltransferases, SIRT1, and Polycomb Members to Promoter CpG Islands

    Heather M. O'Hagan;Wei Wang;Subhojit Sen;Christina DeStefano Shields

  • Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.

    Liam Chung;Erik Thiele Orberg;Abby L. Geis;June L. Chan

  • Polyamine catabolism contributes to enterotoxigenic Bacteroides fragilis-induced colon tumorigenesis.

    Andrew C. Goodwin;Christina E. Destefano Shields;Shaoguang Wu;David L. Huso

  • The Human Tumor Atlas Network: Charting Tumor Transitions Across Space and Time at Single-Cell Resolution

    Orit Rozenblatt-Rosen;Aviv Regev;Aviv Regev;Aviv Regev;Philipp Oberdoerffer;Tal Nawy

  • A dynamic partnership: celebrating our gut flora.

    Cynthia L. Sears

  • Enterotoxigenic Bacteroides fragilis: a Rogue among Symbiotes

    Cynthia L. Sears

  • Bacteroides fragilis enterotoxin cleaves the zonula adherens protein, E-cadherin

    Shaoguang Wu;Kuei Cheng Lim;Julie Huang;Roxan F. Saidi

  • Bacteroides fragilis enterotoxin induces c-Myc expression and cellular proliferation

    Shaoguang Wu;Patrice J. Morin;Djik Maouyo;Cynthia L. Sears

  • Oncogenic Kras Activates a Hematopoietic-to-Epithelial IL-17 Signaling Axis in Preinvasive Pancreatic Neoplasia

    Florencia McAllister;Jennifer M. Bailey;Janivette Alsina;Christopher J. Nirschl

  • Bacteroides fragilis subverts mucosal biology: from symbiont to colon carcinogenesis

    Cynthia L. Sears;Abby L. Geis;Franck Housseau

  • Metabolism links bacterial biofilms and colon carcinogenesis

    Caroline H. Johnson;Christine M. Dejea;David Edler;Linh T. Hoang

Frequent Co-Authors

Franck Housseau
Franck Housseau Johns Hopkins University School of Medicine
Drew M. Pardoll
Drew M. Pardoll Johns Hopkins University School of Medicine
David L. Huso
David L. Huso Johns Hopkins University
Robert A. Anders
Robert A. Anders Johns Hopkins University School of Medicine
Bert Vogelstein
Bert Vogelstein Johns Hopkins University
Kenneth W. Kinzler
Kenneth W. Kinzler Johns Hopkins University
Luis A. Diaz
Luis A. Diaz Memorial Sloan Kettering Cancer Center
Francis M. Giardiello
Francis M. Giardiello Johns Hopkins University School of Medicine
Elizabeth M. Jaffee
Elizabeth M. Jaffee Johns Hopkins University
Nickolas Papadopoulos
Nickolas Papadopoulos Johns Hopkins University School of Medicine

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