Member of the European Molecular Biology Organization (EMBO)
Genetics, RNA, Viral evolution, RNA virus and Evolutionary biology are his primary areas of study. As part of his studies on Genetics, Santiago F. Elena frequently links adjacent subjects like Virology. His work carried out in the field of Viral evolution brings together such families of science as Adaptation, Plant virus and Mutation rate.
His Adaptation study combines topics in areas such as Host and Genetic diversity. His RNA virus study combines topics from a wide range of disciplines, such as Proofreading, Mutant and Viral replication. His Evolutionary biology research includes themes of Epistasis, Fitness landscape, Natural selection and Human evolutionary genetics.
Santiago F. Elena mostly deals with Genetics, Viral evolution, Virology, RNA and Gene. RNA virus, Genome, Virus, Plant virus and Mutation rate are among the areas of Genetics where the researcher is concentrating his efforts. His Mutation rate research is multidisciplinary, relying on both Fitness landscape, Mutant and Robustness.
His Viral evolution research is multidisciplinary, incorporating elements of Evolutionary biology, Epistasis, Molecular evolution and Adaptation, Experimental evolution. His Virology study which covers Phylogenetic tree that intersects with Phylogenetics. Santiago F. Elena focuses mostly in the field of RNA, narrowing it down to topics relating to Viral replication and, in certain cases, Evolutionary dynamics.
Santiago F. Elena spends much of his time researching Genetics, Viral evolution, Gene, Evolutionary dynamics and Evolutionary biology. His study in Host, Virus, Genetic variation, RNA and Phenotype is carried out as part of his studies in Genetics. His Experimental evolution research extends to the thematically linked field of Viral evolution.
The Experimental evolution study which covers Potyvirus that intersects with Robustness and Mutation rate. The Evolutionary biology study combines topics in areas such as Genome and Clade. His study looks at the relationship between Genome and topics such as Genus, which overlap with Virology and Phylogeography.
His primary areas of investigation include Viral evolution, Virus, Genetics, Evolutionary dynamics and Evolutionary biology. His Viral evolution research includes elements of Host, Multiplicity of infection, Virulence and Viral life cycle. The concepts of his Virus study are interwoven with issues in Adaptation, RNA virus and Computational biology.
His research in Evolutionary dynamics intersects with topics in Human evolutionary genetics and Phenotypic plasticity. His Evolutionary biology research is multidisciplinary, relying on both Clade, Phylogenetic tree, Type species and Virology. His Type species research is multidisciplinary, incorporating elements of Genome and Gene.
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Evolution experiments with microorganisms: the dynamics and genetic bases of adaptation.
Santiago F. Elena;Richard E. Lenski.
Nature Reviews Genetics (2003)
Perspective: Evolution and detection of genetic robustness.
The distribution of fitness effects caused by single-nucleotide substitutions in an RNA virus.
Rafael Sanjuán;Andrés Moya;Santiago F. Elena.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Basic concepts in RNA virus evolution.
Esteban Domingo;Cristina Escarmís;Noemi Sevilla;Andres Moya.
The FASEB Journal (1996)
Test of synergistic interactions among deleterious mutations in bacteria.
Santiago F. Elena;Richard E. Lenski.
Punctuated Evolution Caused by Selection of Rare Beneficial Mutations
Santiago F. Elena;Vaughn S. Cooper;Richard E. Lenski.
The evolution of sex: empirical insights into the roles of epistasis and drift
J Arjan G M de Visser;Santiago F Elena.
Nature Reviews Genetics (2007)
Exponential increases of RNA virus fitness during large population transmissions
Isabel S. Novella;Elizabeth A. Duarte;Santiago F. Elena;Andres Moya.
Proceedings of the National Academy of Sciences of the United States of America (1995)
Clonal interference and the evolution of RNA viruses.
Rosario Miralles;Philip J. Gerrish;Andrés Moya;Santiago F. Elena.
Adaptive Value of High Mutation Rates of RNA Viruses: Separating Causes from Consequences
Santiago F. Elena;Rafael Sanjuán.
Journal of Virology (2005)
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