World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
74
Citations
22566
World Ranking
1560
National Ranking
683

Overview

John J. Holland was affiliated with the University of California, San Diego in the United States. Their research primarily focused on the field of Medicine, with particular attention to Pulmonary and Respiratory Medicine, Radiology, Nuclear Medicine and Imaging, Cardiology and Cardiovascular Medicine, Radiation, and Endocrinology, Diabetes and Metabolism.

Their scholarly output included work on several key topics, such as:

  • Lung Cancer Diagnosis and Treatment
  • Advanced Radiotherapy Techniques
  • Effects of Radiation Exposure
  • Diabetes Treatment and Management
  • Metabolism, Diabetes, and Cancer
  • Pharmacology and Obesity Treatment
  • Renal Transplantation Outcomes and Treatments

Among their recent published papers were:

  • Angiotensin Receptor Blockade and Stereotactic Body Radiation Therapy for Early Stage Lung Cancer, 2021, Research Square (Research Square)
  • Semaglutide as an Aid to Weight Reduction in Adults With Obesity and Advanced CKD, 2022, Journal of the American Society of Nephrology
  • Comprehensive Geriatric Assessment (CGA) and Optimisation Services before Kidney Transplantation in Older Potential Recipients: Results from the First UK-Wide Transplant Centre Survey Study, 2024, Journal of the American Society of Nephrology
  • Postoperative cardiovascular and renal complications, 2024, Medicine

Their work appeared most frequently in the Journal of the American Society of Nephrology, with additional publications in Research Square and Medicine.

During their career, John J. Holland collaborated often with colleagues including Lauren Maloney, Garth W. Tormoen, Emile Latour, Yiyi Chen, and Douglas R. Rice.

Best Publications

  • RNA virus mutations and fitness for survival

    E. Domingo;J. J. Holland

  • Rapid evolution of RNA genomes

    John Holland;Katherine Spindler;Katherine Spindler;Frank Horodyski;Elizabeth Grabau

  • Mutation rates among RNA viruses

    John W. Drake;John J. Holland

  • Rapid Evolution of RNA Viruses

    D A Steinhauer;J J Holland

  • Origin and evolution of viruses

    John Holland;Esteban Domingo

  • RNA virus populations as quasispecies.

    J. J. Holland;J. C. De La Torre;D. A. Steinhauer

  • The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review

    Esteban Domingo;Encarnación Martínez-Salas;Francisco Sobrino;Juan Carlos de la Torre

  • Basic concepts in RNA virus evolution.

    Esteban Domingo;Cristina Escarmís;Noemi Sevilla;Andres Moya

  • Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase.

    David A. Steinhauer;Esteban Domingo;John J. Holland

  • Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses.

    J J Holland;J C de la Torre;D K Clarke;E Duarte

  • Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis.

    John J. Holland;Esteban Domingo;Juan Carlos de la Torre;David A. Steinhauer

  • Exponential increases of RNA virus fitness during large population transmissions

    Isabel S. Novella;Elizabeth A. Duarte;Santiago F. Elena;Andres Moya

  • Genetic and Fitness Changes Accompanying Adaptation of an Arbovirus to Vertebrate and Invertebrate Cells

    Scott C. Weaver;Aaron C. Brault;Wenli Kang;John J. Holland

  • Effects of defective interfering viruses on virus replication and pathogenesis in vitro and in vivo.

    Laurent Roux;Anne E. Simon;John J. Holland

  • RNA virus quasispecies: significance for viral disease and epidemiology.

    E. A. Duarte;I. S. Novella;Scott Weaver;E. Domingo

  • RNA virus quasispecies populations can suppress vastly superior mutant progeny.

    J C de la Torre;J J Holland

  • Direct method for quantitation of extreme polymerase error frequencies at selected single base sites in viral RNA.

    D A Steinhauer;J J Holland

  • Genetic bottlenecks and population passages cause profound fitness differences in RNA viruses.

    D K Clarke;E A Duarte;A Moya;S F Elena

  • Mechanism of rejection of virus persistently infected tumor cells by athymic nude mice.

    Nagahiro Minato;Nagahiro Minato;Barry R. Bloom;Barry R. Bloom;Charlotte Jones;Charlotte Jones;John Holland;John Holland

  • Persistent Noncytocidal Vesicular Stomatitis Virus Infections Mediated by Defective T Particles that Suppress Virion Transcriptase

    John J. Holland;Louis Perez Villarreal

Frequent Co-Authors

Esteban Domingo
Esteban Domingo Centro de Biología Molecular Severo Ochoa
David A. Steinhauer
David A. Steinhauer Emory University
Bert L. Semler
Bert L. Semler University of California, Irvine
Santiago F. Elena
Santiago F. Elena Santa Fe Institute
Andrés Moya
Andrés Moya University of Valencia
Josep Quer
Josep Quer Instituto de Salud Carlos III
Cristina Escarmís
Cristina Escarmís Spanish National Research Council
Francisco Sobrino
Francisco Sobrino Spanish National Research Council
Scott C. Weaver
Scott C. Weaver The University of Texas Medical Branch at Galveston
Luis Menéndez-Arias
Luis Menéndez-Arias Spanish National Research Council

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Exploring microbiology opens doors to a variety of career paths, many of which can be enhanced or supported by related online degrees. For those interested in healthcare careers, becoming a functional medicine nurse offers a specialized route combining biology and patient care, with strong growth potential.

Additionally, careers in medical coding and health information management are accessible through certifications like the cpc certification. This certification allows individuals to work in healthcare settings by managing medical records and billing, which complements microbiology knowledge for roles focused on clinical work.

For students or professionals facing unique challenges, understanding options such as the best degree for a convicted felon can help them find pathways to gainful employment. Many online programs provide flexible, accessible education suited to diverse backgrounds.

Some microbiology graduates also explore roles in child health and development, where awareness of the child specialist salary can guide career decisions and expectations. Online coursework paired with hands-on experience supports entry into these rewarding fields.

Best Scientists Citing John J. Holland