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David A. Steinhauer

David A. Steinhauer

D-Index & Metrics

Microbiology

D-Index
47
Citations
11759
World Ranking
4747
National Ranking
1829

Overview

David A. Steinhauer is affiliated with Emory University in the United States, with a research focus spanning medicine, biochemistry, genetics, and molecular biology. Their work emphasizes epidemiology and molecular biology, along with specific interests in radiology, nuclear medicine, imaging, organic chemistry, and agronomy and crop science.

The core of Steinhauer's research centers on influenza virus studies, glycosylation and glycoproteins, and respiratory viral infections. Additional focal areas include carbohydrate chemistry and synthesis, animal disease management and epidemiology, monoclonal and polyclonal antibodies research, as well as SARS-CoV-2 and COVID-19 research.

Notable recent papers authored or co-authored by Steinhauer include:

  • The Human Lung Glycome Reveals Novel Glycan Ligands for Influenza A Virus (2020, Scientific Reports)
  • Characterizing Emerging Canine H3 Influenza Viruses (2020, PLoS Pathogens)
  • Sialylated and sulfated N-Glycans in MDCK and engineered MDCK cells for influenza virus studies (2022, Scientific Reports)
  • SARS-CoV-2 and other coronaviruses bind to phosphorylated glycans from the human lung (2021, Virology)
  • Molecular epidemiology and glycomics of swine influenza viruses circulating in commercial swine farms in the southeastern and midwest United States (2020, Veterinary Microbiology)

Frequent co-authors collaborating with Steinhauer include Lauren Byrd-Leotis, Richard D. Cummings, Yoshihiro Kawaoka, Nan Jia, and Yasuyuki Matsumoto. These collaborations have contributed to several papers across diverse publication venues.

Publication venues where Steinhauer's work appears regularly include:

  • Scientific Reports
  • Virology
  • PLoS Pathogens
  • Veterinary Microbiology
  • Apollo (University of Cambridge)

Steinhauer's contributions to the academic community highlight multidisciplinary approaches integrating virology, glycomics, and epidemiology, with implications for understanding influenza viruses and emerging respiratory pathogens.

Best Publications

  • Role of hemagglutinin cleavage for the pathogenicity of influenza virus.

    David A. Steinhauer

  • The structure and receptor binding properties of the 1918 influenza hemagglutinin.

    S. J. Gamblin;L. F. Haire;R. J. Russell;D. J. Stevens

  • Rapid Evolution of RNA Viruses

    D A Steinhauer;J J Holland

  • RNA virus populations as quasispecies.

    J. J. Holland;J. C. De La Torre;D. A. Steinhauer

  • Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.

    Jue Chen;Kon Ho Lee;David A Steinhauer;David J Stevens

  • The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance — a review

    Esteban Domingo;Encarnación Martínez-Salas;Francisco Sobrino;Juan Carlos de la Torre

  • Lack of evidence for proofreading mechanisms associated with an RNA virus polymerase.

    David A. Steinhauer;Esteban Domingo;John J. Holland

  • Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion

    Rupert J. Russell;Philip S. Kerry;David J. Stevens;David A. Steinhauer

  • Mutation frequencies at defined single codon sites in vesicular stomatitis virus and poliovirus can be increased only slightly by chemical mutagenesis.

    John J. Holland;Esteban Domingo;Juan Carlos de la Torre;David A. Steinhauer

  • Genetics of influenza viruses.

    David A. Steinhauer;John J. Skehel

  • Influenza HA Subtypes Demonstrate Divergent Phenotypes for Cleavage Activation and pH of Fusion: Implications for Host Range and Adaptation

    Summer E. Galloway;Mark L. Reed;Charles J. Russell;Charles J. Russell;David A. Steinhauer

  • Direct method for quantitation of extreme polymerase error frequencies at selected single base sites in viral RNA.

    D A Steinhauer;J J Holland

  • Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutinin.

    D A Steinhauer;S A Wharton;J J Skehel;D C Wiley

  • Introduction of intersubunit disulfide bonds in the membrane-distal region of the influenza hemagglutinin abolishes membrane fusion activity

    L. Godley;J. Pfeifer;D. Steinhauer;B. Ely

  • The Interplay between the Host Receptor and Influenza Virus Hemagglutinin and Neuraminidase

    Lauren Byrd-Leotis;Richard D. Cummings;David A. Steinhauer

  • Studies of the binding properties of influenza hemagglutinin receptor-site mutants.

    Javier Martín;Stephen A. Wharton;Yi Pu Lin;Darin K. Takemoto

  • Composition and Functions of the Influenza Fusion Peptide

    Karen J. Cross;William A. Langley;Rupert J. Russell;John J. Skehel

  • Amantadine selection of a mutant influenza virus containing an acid-stable hemagglutinin glycoprotein: evidence for virus-specific regulation of the pH of glycoprotein transport vesicles

    David A. Steinhauer;Stephen A. Wharton;John J. Skehel;Don C. Wiley

  • Electron microscopy of antibody complexes of influenza virus haemagglutinin in the fusion pH conformation.

    S. A. Wharton;L. J. Calder;R. W. H. Ruigrok;J. J. Skehel

  • Influenza a viruses with mutations in the m1 helix six domain display a wide variety of morphological phenotypes.

    Laura M. Burleigh;Lesley J. Calder;John J. Skehel;David A. Steinhauer;David A. Steinhauer

  • Genetics of influenza viruses

    Peter Palese;David W. Kingsbury

Frequent Co-Authors

John J. Skehel
John J. Skehel The Francis Crick Institute
Richard D. Cummings
Richard D. Cummings Harvard Medical School
Don C. Wiley
Don C. Wiley Harvard University
John J. Holland
John J. Holland University of California, San Diego
David F. Smith
David F. Smith Emory University
Esteban Domingo
Esteban Domingo Centro de Biología Molecular Severo Ochoa
Richard K. Plemper
Richard K. Plemper Georgia State University
Richard W. Compans
Richard W. Compans Emory University
Ralph A. Tripp
Ralph A. Tripp University of Georgia
Charles J. Russell
Charles J. Russell St. Jude Children's Research Hospital

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