World's Best Scientists 2026 revealed!

D-Index & Metrics

Microbiology

D-Index
113
Citations
60721
World Ranking
213
National Ranking
29

Medicine

D-Index
112
Citations
60654
World Ranking
5068
National Ranking
499

Research.com Recognitions

  • 2014 - Member of the National Academy of Sciences
  • 1992 - Member of Academia Europaea
  • 1987 - Robert Koch Prize
  • 1984 - Fellow of the Royal Society, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Member of the European Molecular Biology Organization (EMBO)

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Virus

His primary scientific interests are in Virus, Virology, Biochemistry, Protein structure and Influenza A virus. His research in Virus intersects with topics in Transcription, Mutant and Glycoprotein. John J. Skehel combines subjects such as Antibody and Antigen with his study of Virology.

The various areas that he examines in his Protein structure study include Conformational change, Peptide sequence and Lipid bilayer fusion. His Lipid bilayer fusion research integrates issues from Ectodomain and Protein folding. His Influenza A virus study combines topics from a wide range of disciplines, such as Receptor, N-Acetylneuraminic acid and Binding site.

His most cited work include:

  • Atomic structure of the ectodomain from HIV-1 gp41 (1476 citations)
  • Structure of influenza haemagglutinin at the pH of membrane fusion (1375 citations)
  • The Structure and Function of the Hemagglutinin Membrane Glycoprotein of Influenza Virus (1193 citations)

What are the main themes of his work throughout his whole career to date?

John J. Skehel spends much of his time researching Virology, Virus, Hemagglutinin, Biochemistry and Lipid bilayer fusion. His work carried out in the field of Virology brings together such families of science as Antibody and Antigen. His studies in Virus integrate themes in fields like Molecular biology and Glycoprotein.

The study incorporates disciplines such as T cell, Conformational change, Stereochemistry, Epitope and Binding site in addition to Hemagglutinin. The concepts of his Lipid bilayer fusion study are interwoven with issues in Viral entry, Biophysics and Ectodomain. John J. Skehel has included themes like Receptor and Influenza A virus subtype H5N1 in his Viral protein study.

He most often published in these fields:

  • Virology (59.49%)
  • Virus (55.38%)
  • Hemagglutinin (26.15%)

What were the highlights of his more recent work (between 2004-2021)?

  • Virology (59.49%)
  • Virus (55.38%)
  • Hemagglutinin (26.15%)

In recent papers he was focusing on the following fields of study:

John J. Skehel mostly deals with Virology, Virus, Hemagglutinin, Influenza A virus and Receptor. The Neuraminidase, Influenza A virus subtype H5N1 and Orthomyxoviridae research he does as part of his general Virology study is frequently linked to other disciplines of science, such as H5N1 genetic structure, therefore creating a link between diverse domains of science. Many of his studies on Virus involve topics that are commonly interrelated, such as Binding site.

His research integrates issues of Epitope, Biophysics and Lipid bilayer fusion in his study of Hemagglutinin. His Receptor research is multidisciplinary, incorporating perspectives in Protein structure, Plasma protein binding, Avidity and Viral protein. As a part of the same scientific family, he mostly works in the field of Biochemistry, focusing on Viral entry and, on occasion, Glycoprotein and Simian immunodeficiency virus.

Between 2004 and 2021, his most popular works were:

  • A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins (940 citations)
  • The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design (653 citations)
  • Structure of an unliganded simian immunodeficiency virus gp120 core (481 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Gene
  • Virus

His primary areas of investigation include Virology, Virus, Influenza A virus, Hemagglutinin and Receptor. His study in Virology is interdisciplinary in nature, drawing from both Antibody and Monoclonal antibody. John J. Skehel has researched Virus in several fields, including Sialic acid, Binding site and Microbiology.

Hemagglutinin is the subject of his research, which falls under Biochemistry. His Receptor study which covers Viral protein that intersects with Plasma protein binding, Mutant and Avidity. His Lipid bilayer research focuses on Viral entry and how it relates to Simian immunodeficiency virus, Gp41 and Glycoprotein.

Best Publications

  • Receptor Binding and Membrane Fusion in Virus Entry: The Influenza Hemagglutinin

    John J. Skehel;Don C. Wiley

  • Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution.

    I. A. Wilson;J. J. Skehel;D. C. Wiley

  • Structural identification of the antibody-binding sites of Hong Kong influenza haemagglutinin and their involvement in antigenic variation

    D. C. Wiley;I. A. Wilson;J. J. Skehel

  • Atomic structure of the ectodomain from HIV-1 gp41

    W. Weissenhorn;A. Dessen;S. C. Harrison;S. C. Harrison;J. J. Skehel

  • The Structure and Function of the Hemagglutinin Membrane Glycoprotein of Influenza Virus

    Don C. Wiley;John J. Skehel

  • Structure of influenza haemagglutinin at the pH of membrane fusion

    Per A. Bullough;Frederick M. Hughson;John J. Skehel;Don C. Wiley;Don C. Wiley

  • Structure of the influenza virus haemagglutinin complexed with its receptor, sialic acid

    W. Weis;J. H. Brown;S. Cusack;S. Cusack;J. C. Paulson

  • A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins

    Davide Corti;Jarrod Voss;Steven J. Gamblin;Giosiana Codoni

  • Printed covalent glycan array for ligand profiling of diverse glycan binding proteins

    Ola Blixt;Steve Head;Tony Mondala;Christopher Scanlan

  • The molecular basis of the specific anti-influenza action of amantadine.

    A J Hay;A J Wolstenholme;J J Skehel;M H Smith

  • The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design

    Rupert J. Russell;Lesley F. Haire;David J. Stevens;Patrick J. Collins

  • Changes in the conformation of influenza virus hemagglutinin at the pH optimum of virus-mediated membrane fusion.

    J J Skehel;P M Bayley;E B Brown;S R Martin

  • The structure and receptor binding properties of the 1918 influenza hemagglutinin.

    S. J. Gamblin;L. F. Haire;R. J. Russell;D. J. Stevens

  • Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity

    G. N. Rogers;J. C. Paulson;R. S. Daniels;J. J. Skehel

  • Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion.

    Donald J. Benton;Antoni G. Wrobel;Pengqi Xu;Pengqi Xu;Chloë Roustan

  • Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors

    Shinya Yamada;Yasuo Suzuki;Takashi Suzuki;Mai Q. Le

  • Influenza Hemagglutinin and Neuraminidase Membrane Glycoproteins

    Steven J. Gamblin;John J. Skehel

  • Structure of an unliganded simian immunodeficiency virus gp120 core.

    Bing Chen;Erik M. Vogan;Erik M. Vogan;Haiyun Gong;John J. Skehel

  • Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformation.

    Jue Chen;Kon Ho Lee;David A Steinhauer;David J Stevens

  • X-ray structures of H5 avian and H9 swine influenza virus hemagglutinins bound to avian and human receptor analogs.

    Ya Ha;David J. Stevens;John J. Skehel;Don C. Wiley

  • A carbohydrate side chain on hemagglutinins of Hong Kong influenza viruses inhibits recognition by a monoclonal antibody

    J J Skehel;D J Stevens;R S Daniels;A R Douglas

Frequent Co-Authors

Don C. Wiley
Don C. Wiley Harvard University
David A. Steinhauer
David A. Steinhauer Emory University
Stephen C. Harrison
Stephen C. Harrison Harvard University
Steven J. Gamblin
Steven J. Gamblin The Francis Crick Institute
Alan J. Hay
Alan J. Hay Medical Research Council
John W. McCauley
John W. McCauley The Francis Crick Institute
Stephen R. Martin
Stephen R. Martin The Francis Crick Institute
Ian A. Wilson
Ian A. Wilson Scripps Research Institute
Winfried Weissenhorn
Winfried Weissenhorn Grenoble Alpes University
James C. Paulson
James C. Paulson Scripps Research Institute

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying microbiology in the USA opens doors to a variety of related online degrees and career paths. For individuals with unique backgrounds, including those seeking the best degree for felons, there are flexible online options that provide accessible education opportunities in science and healthcare fields.

One rapidly growing pathway is becoming a functional medicine nurse practitioner. This profession combines health sciences with holistic care, offering a rewarding career that benefits from a strong foundation in biological and microbiological concepts.

Additionally, the healthcare industry demands skilled professionals in administrative roles, such as medical coding. Obtaining a certified professional coder certification can lead to lucrative positions that support clinical data management, an essential part of healthcare systems.

For graduates interested in leadership and data management, a degree in health information management is a smart option. The health information management bachelor degree salary reflects strong demand for professionals who ensure the accuracy and security of patient data.

Best Scientists Citing John J. Skehel

Trending Scientists

Recently Published Articles