World's Best Scientists 2026 revealed!

D-Index & Metrics

Immunology

D-Index
63
Citations
22487
World Ranking
2980
National Ranking
1402

John J. Letterio publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where John J. Letterio sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 173 publications — 24th percentile

24% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

John J. Letterio D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where John J. Letterio sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 63 D-Index — 40th percentile

40% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

John J. Letterio is affiliated with Case Western Reserve University in the United States. Their research primarily focuses on medicine and the intersecting disciplines of biochemistry, genetics, and molecular biology. Among their explored subfields are molecular biology, oncology, immunology, hematology, and artificial intelligence.

The scientist's recent scholarly contributions include studies on COVID-19 epidemiology and its broader pandemic impacts, childhood cancer survivors' quality of life, genetic factors in colorectal cancer, cancer immunotherapy and biomarkers, as well as topics involving genomics, phytochemicals, oxidative stress, and glutathione transferases and polymorphisms.

Recent papers authored or coauthored by John J. Letterio include:

  • Estimating the prevalence and risk of COVID-19 among international travelers and evacuees of Wuhan through modeling and case reports, 2020, PLoS ONE
  • Loss of p27Kip1 leads to expansion of CD4+ effector memory T cells and accelerates colitis-associated colon cancer in mice with a T cell lineage restricted deletion of Smad4, 2020, OncoImmunology
  • Tm4sf19 deficiency inhibits osteoclast multinucleation and prevents bone loss, 2023, Metabolism
  • Smad4-deficient T cells promote colitis-associated colon cancer via an IFN-γ-dependent suppression of 15-hydroxyprostaglandin dehydrogenase, 2022, Frontiers in Immunology
  • Modeling and Predicting Antibody Durability for mRNA-1273 Vaccine for SARS-CoV-2 Variants, 2021, bioRxiv (Cold Spring Harbor Laboratory)

Their frequent collaborators include researchers such as George Luo, Byung-Gyu Kim, Alex Y. Huang, Sung Hee Choi, and Toby Chen.

John J. Letterio's work has been published in various scientific venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • PLoS ONE
  • OncoImmunology
  • Metabolism
  • Frontiers in Immunology

Best Publications

  • REGULATION OF IMMUNE RESPONSES BY TGF-β*

    John James Letterio;Anita B. Roberts

  • TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

    Julien C. Marie;John James Letterio;Marc Gavin;Alexander Y. Rudensky

  • Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response.

    Gillian S. Ashcroft;Xiao Yang;Adam B. Glick;Michael Weinstein

  • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-β

    Xiao Yang;John J. Letterio;Robert J. Lechleider;Lin Chen

  • CD4+CD25+ Regulatory T Cells Can Mediate Suppressor Function in the Absence of Transforming Growth Factor β1 Production and Responsiveness

    Ciriaco A. Piccirillo;John J. Letterio;Angela M. Thornton;Rebecca S. McHugh

  • Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance Abrogation Prevents Tumor Recurrence

    Masaki Terabe;So Matsui;Jong-Myun Park;Mizuko Mamura

  • A Role for Endogenous Transforming Growth Factor β1 in Langerhans Cell Biology: The Skin of Transforming Growth Factor β1 Null Mice Is Devoid of Epidermal Langerhans Cells

    Teresa A. Borkowski;John J. Letterio;Andrew G. Farr;Mark C. Udey

  • Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance

    Stephanie Dillon;Sudhanshu Agrawal;Kaustuv Banerjee;John Letterio

  • Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects

    Yu An Yang;Oksana Dukhanina;Binwu Tang;Mizuko Mamura

  • IL-13 Activates a Mechanism of Tissue Fibrosis That Is Completely TGF-β Independent

    Mallika Kaviratne;Matthias Hesse;Mary Leusink;Allen W. Cheever

  • Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis.

    Marika C. Kullberg;Dragana Jankovic;Peter L. Gorelick;Patricia Caspar

  • A Novel Synthetic Oleanane Triterpenoid, 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic Acid, with Potent Differentiating, Antiproliferative, and Anti-Inflammatory Activity

    Nanjoo Suh;Yongping Wang;Tadashi Honda;Gordon W. Gribble

  • Smad4 signalling in T cells is required for suppression of gastrointestinal cancer

    Byung Gyu Kim;Cuiling Li;Wenhui Qiao;Mizuko Mamura

  • Cdk5 disruption attenuates tumor PD-L1 expression and promotes antitumor immunity

    R. Dixon Dorand;Joseph Nthale;Joseph Nthale;Jay T. Myers;Jay T. Myers;Deborah S. Barkauskas;Deborah S. Barkauskas

  • Factors involved in the differentiation of TGF-beta-producing cells from naive CD4+ T cells: IL-4 and IFN-gamma have opposing effects, while TGF-beta positively regulates its own production.

    Robert A. Seder;Thomas Marth;Myra C. Sieve;Warren Strober

  • Autoimmunity associated with TGF-β1-deficiency in mice is dependent on MHC class II antigen expression

    John J. Letterio;Andrew G. Geiser;Ashok B. Kulkarni;Howard Dang

  • Biology of TGF-β in knockout and transgenic mouse models

    Erwin P. Böttinger;John J. Letterio;Anita B. Roberts

  • SLE-like autoantibodies and Sjögren's syndrome-like lymphoproliferation in TGF-beta knockout mice.

    Howard Dang;Andrew G. Geiser;John J. Letterio;Toru Nakabayashi

  • Targeting Improves MSC Treatment of Inflammatory Bowel Disease

    In Kap Ko;Byung Gyu Kim;Amad Awadallah;Jenifer Mikulan

  • Transforming growth factor beta 1 (TGF-beta 1) controls expression of major histocompatibility genes in the postnatal mouse: aberrant histocompatibility antigen expression in the pathogenesis of the TGF-beta 1 null mouse phenotype

    Andrew G. Geiser;John J. Letterio;Ashok B. Kulkarni;Stefan Karlsson

Frequent Co-Authors

Anita B. Roberts
Anita B. Roberts National Institutes of Health
Michael B. Sporn
Michael B. Sporn Dartmouth College
Ashok B. Kulkarni
Ashok B. Kulkarni National Institutes of Health
Eric Lam
Eric Lam Sun Yat-sen University
Marcos de Lima
Marcos de Lima The Ohio State University
Kathleen C. Flanders
Kathleen C. Flanders National Institutes of Health
Seong-Jin Kim
Seong-Jin Kim Seoul National University
Yoram Vodovotz
Yoram Vodovotz University of Pittsburgh
Chu-Xia Deng
Chu-Xia Deng University of Macau
Peter D. Aplan
Peter D. Aplan National Institutes of Health

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