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Jean-Claude Labbé

Jean-Claude Labbé

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
15273
World Ranking
11822
National Ranking
429

Overview

Jean-Claude Labbé is affiliated with the University of Montpellier in France. Their research primarily focuses on biochemistry, genetics, and molecular biology, with significant contributions across 26 publications in these fields. Within these areas, their subfields of study include aging, molecular biology, endocrine and autonomic systems, cell biology, and public health, environmental and occupational health.

The scientist's work covers a range of topics related to genetics, aging, and longevity in model organisms, circadian rhythm and melatonin, reproductive biology and fertility, photosynthetic processes and mechanisms, cellular mechanics and interactions, spaceflight effects on biology, and microtubule and mitosis dynamics.

Jean-Claude Labbé has published research in several academic venues, including UNC Libraries, bioRxiv (Cold Spring Harbor Laboratory), PubMed, Frontiers in Cell and Developmental Biology, and Molecular Biology of the Cell.

Frequent coauthors collaborating with Jean-Claude Labbé include Abigail R. Gerhold, Vincent Poupart, Réda M. Zellag, Eugénie Goupil, and Léa Lacroix.

Among recent papers authored by or involving Jean-Claude Labbé are:

  • Uncoupling cell division and cytokinesis during germline development in metazoans, 2022, Frontiers in Cell and Developmental Biology
  • The initial expansion of the C. elegans syncytial germ line is coupled to incomplete primordial germ cell cytokinesis, 2021, Development
  • CentTracker: a trainable, machine-learning-based tool for large-scale analyses of Caenorhabditis elegans germline stem cell mitosis, 2021, Molecular Biology of the Cell
  • Phosphoproteomic analysis identifies supervillin as an ERK3 substrate regulating cytokinesis and cell ploidy, 2022, Journal of Cellular Physiology
  • OSGN-1 is a conserved flavin-containing monooxygenase required to stabilize the intercellular bridge in late cytokinesis, 2024, Proceedings of the National Academy of Sciences

Best Publications

  • In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase

    M. Peter;J. Nakagawa;M. Dorée;J.C. Labbé

  • Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

    Andrew Burgess;Suzanne Vigneron;Estelle Brioudes;Jean-Claude Labbé

  • Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein.

    U. Strausfeld;J. C. Labbé;D. Fesquet;J. C. Cavadore

  • MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B

    J.-C. Labbe;J.-P. Capony;D. Caput;J.-C. Cavadore

  • The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues

    D Fesquet;J C Labbé;J Derancourt;J P Capony

  • Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs.

    Fulvia Verde;Jean Claude Labbé;Marcel Dorée;Eric Karsenti

  • Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation.

    J.C. Labbe;A. Picard;G. Peaucellier;J.C. Cavadore

  • Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

    Ariane Abrieu;Laura Magnaghi-Jaulin;Jason A. Kahana;Marion Peter

  • Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

    M. Peter;J. Nakagawa;M. Dorée;J.C. Labbé

  • The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

    Aicha Gharbi-Ayachi;Jean-Claude Labbé;Andrew Burgess;Suzanne Vigneron

  • Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2 +

    J. C. Labbe;M. G. Lee;P. Nurse;A. Picard

  • The anaphase-promoting complex: a key factor in the regulation of cell cycle.

    Anna Castro;Cyril Bernis;Suzanne Vigneron;Jean-Claude Labbé

  • CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans.

    S. Felkai;J.J. Ewbank;J. Lemieux;J.‐C Labbé

  • The Expanding Roles of Gβγ Subunits in G Protein–Coupled Receptor Signaling and Drug Action

    Shahriar M. Khan;Rory Sleno;Sarah Gora;Peter Zylbergold

  • MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK.

    A. Devault;A. M. Martinez;D. Fesquet;J. C. Labbé

  • Triggering of cyclin degradation in interphase extracts of amphibian eggs by cdc2 kinase

    Marie-Anne Félix;Jean-Claude Labbé;Marcel Dorée;Tim Hunt

  • Kinetochore Localization of Spindle Checkpoint Proteins: Who Controls Whom?

    Suzanne Vigneron;Susana Prieto;Cyril Bernis;Jean-Claude Labbé

  • Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

    Thierry Lorca;Anna Castro;Anne‐Marie Martinez;Suzanne Vigneron

  • The Polo-like kinase Plx1 is a component of the MPF amplification loop at the G2/M-phase transition of the cell cycle in Xenopus eggs

    Ariane Abrieu;Thierry Brassac;Simon Galas;Daniel Fisher

  • Activation of p34cdc2 protein kinase by microinjection of human cdc25C into mammalian cells. Requirement for prior phosphorylation of cdc25C by p34cdc2 on sites phosphorylated at mitosis.

    U. Strausfeld;A. Fernandez;J.-P. Capony;F. Girard

Frequent Co-Authors

Marcel Dorée
Marcel Dorée Centre national de la recherche scientifique, CNRS
Thierry Lorca
Thierry Lorca University of Montpellier
Ned J. C. Lamb
Ned J. C. Lamb Centre national de la recherche scientifique, CNRS
Anne Fernandez
Anne Fernandez Centre national de la recherche scientifique, CNRS
Erich A. Nigg
Erich A. Nigg University of Basel
Bernard Monsarrat
Bernard Monsarrat Federal University of Toulouse Midi-Pyrénées
Eric Karsenti
Eric Karsenti École Normale Supérieure
Gilles Labesse
Gilles Labesse Grenoble Alpes University
Claude Prigent
Claude Prigent University of Rennes
Kjetil Taskén
Kjetil Taskén Oslo University Hospital

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