His primary areas of investigation include Cyclin-dependent kinase 1, Biochemistry, Cell biology, Mitosis and Cyclin-dependent kinase 3. While the research belongs to areas of Cyclin-dependent kinase 1, Jean-Claude Labbé spends his time largely on the problem of Protein kinase A, intersecting his research to questions surrounding Molecular biology. All of his Biochemistry and Cyclin-dependent kinase complex, Cyclin B and Phosphorylation investigations are sub-components of the entire Biochemistry study.
In his research on the topic of Cyclin B, Cyclin A2 and Cyclin A is strongly related with Cyclin D. His research in Cell biology intersects with topics in Mad2, Anaphase, CDC20, Spindle checkpoint and Cullin. The Mitosis study combines topics in areas such as Cell nucleus, Nuclear lamina and Mitotic M phase.
Jean-Claude Labbé mostly deals with Cell biology, Cyclin-dependent kinase 1, Mitosis, Biochemistry and Molecular biology. His studies deal with areas such as Cell cycle and Cyclin A as well as Cell biology. The study incorporates disciplines such as Cyclin D and Cyclin B in addition to Cyclin A.
His research investigates the connection with Cyclin D and areas like Cyclin-dependent kinase complex which intersect with concerns in Cyclin A2 and Cyclin-dependent kinase 3. His Cyclin-dependent kinase 1 course of study focuses on Cyclin-dependent kinase 2 and Mitogen-activated protein kinase kinase. As a part of the same scientific study, Jean-Claude Labbé usually deals with the Mitosis, concentrating on Anaphase and frequently concerns with Cell cycle checkpoint.
His main research concerns Cell biology, Cyclin B, Mitosis, Cyclin A and Metallurgy. Jean-Claude Labbé interconnects Cell cycle, Spindle checkpoint, Mad1 and Anaphase-promoting complex in the investigation of issues within Cell biology. Cyclin B and Cyclin-dependent kinase 1 are frequently intertwined in his study.
His Mitosis study incorporates themes from Mitotic exit and Cdc25. His study explores the link between Cyclin A and topics such as Cyclin A2 that cross with problems in Cancer research, Cyclin E, Cyclin-dependent kinase complex and Cyclin D. His research investigates the link between Protein phosphatase 2 and topics such as Dephosphorylation that cross with problems in Cyclin and Molecular biology.
Cell biology, Anaphase-promoting complex, Mitotic exit, Cyclin A and Cyclin B are his primary areas of study. His research in Cell biology is mostly focused on Protein phosphatase 2. His work deals with themes such as Molecular biology, Dephosphorylation and Cyclin A2, Cyclin, which intersect with Protein phosphatase 2.
His study connects Mitosis and Mitotic exit. His Cell division control protein 4 research is multidisciplinary, relying on both APC/C activator protein CDH1, Proteasome, Skp1, CDC20 and Cullin. His BUB3 study combines topics from a wide range of disciplines, such as Mad2, BUB1, Spindle checkpoint, Aurora B kinase and Mad1.
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In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
M. Peter;J. Nakagawa;M. Dorée;J.C. Labbé.
Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein.
U. Strausfeld;J. C. Labbé;D. Fesquet;J. C. Cavadore.
MPF from starfish oocytes at first meiotic metaphase is a heterodimer containing one molecule of cdc2 and one molecule of cyclin B.
J.-C. Labbe;J.-P. Capony;D. Caput;J.-C. Cavadore.
The EMBO Journal (1989)
The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues
D Fesquet;J C Labbé;J Derancourt;J P Capony.
The EMBO Journal (1993)
Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs.
Fulvia Verde;Jean Claude Labbé;Marcel Dorée;Eric Karsenti.
Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase
M. Peter;J. Nakagawa;M. Dorée;J.C. Labbé.
Purification of MPF from starfish: identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation.
J.C. Labbe;A. Picard;G. Peaucellier;J.C. Cavadore.
Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.
Ariane Abrieu;Laura Magnaghi-Jaulin;Jason A. Kahana;Marion Peter.
Activation at M-phase of a protein kinase encoded by a starfish homologue of the cell cycle control gene cdc2 +
J C Labbe;M G Lee;P Nurse;A Picard.
MAT1 ('menage à trois') a new RING finger protein subunit stabilizing cyclin H-cdk7 complexes in starfish and Xenopus CAK.
A. Devault;A. M. Martinez;D. Fesquet;J. C. Labbé.
The EMBO Journal (1995)
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