Thierry Lorca

Overview

Best Publications

• Partial inhibition of Cdk1 in G2 phase overrides the SAC and decouples mitotic events

  Rachael A McCloy;Samuel Rogers;C Elizabeth Caldon;Thierry Lorca

  938
  Citations

• Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance

  Andrew Burgess;Suzanne Vigneron;Estelle Brioudes;Jean-Claude Labbé

  809
  Citations

• The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues

  D Fesquet;J C Labbé;J Derancourt;J P Capony

  574
  Citations

• Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs

  Thierry Lorca;Francisco H. Cruzalegui;Didier Fesquet;Jean-claude Cavadore

  545
  Citations

• Mps1 is a kinetochore-associated kinase essential for the vertebrate mitotic checkpoint.

  Ariane Abrieu;Laura Magnaghi-Jaulin;Jason A. Kahana;Marion Peter

  458
  Citations

• The Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

  Aicha Gharbi-Ayachi;Jean-Claude Labbé;Andrew Burgess;Suzanne Vigneron

  425
  Citations

• The anaphase-promoting complex: a key factor in the regulation of cell cycle.

  Anna Castro;Cyril Bernis;Suzanne Vigneron;Jean-Claude Labbé

  353
  Citations

• Kinetochore Localization of Spindle Checkpoint Proteins: Who Controls Whom?

  Suzanne Vigneron;Susana Prieto;Cyril Bernis;Jean-Claude Labbé

  268
  Citations

• Fizzy is required for activation of the APC/cyclosome in Xenopus egg extracts

  Thierry Lorca;Anna Castro;Anne‐Marie Martinez;Suzanne Vigneron

  261
  Citations

• Greatwall maintains mitosis through regulation of PP2A

  Suzanne Vigneron;Estelle Brioudes;Andrew Burgess;Jean-Claude Labbé

  221
  Citations

• Degradation of the proto-oncogene product p39mos is not necessary for cyclin proteolysis and exit from meiotic metaphase: requirement for a Ca(2+)-calmodulin dependent event.

  T. Lorca;S. Galas;D. Fesquet;A. Devault

  210
  Citations

• APC/Fizzy-Related targets Aurora-A kinase for proteolysis

  Anna Castro;Yannick Arlot-Bonnemains;Suzanne Vigneron;Jean-Claude Labbé

  195
  Citations

• Dephosphorylation of cdc2 on threonine 161 is required for cdc2 kinase inactivation and normal anaphase.

  T Lorca;J C Labbé;A Devault;D Fesquet

  189
  Citations

• The APC is dispensable for first meiotic anaphase in Xenopus oocytes.

  Marion Peter;Anna Castro;Thierry Lorca;Christian Le Peuch

  160
  Citations

• Alterations of anaphase-promoting complex genes in human colon cancer cells

  Qing Wang;Caroline Moyret-Lalle;Florence Couzon;Christine Surbiguet-Clippe

  141
  Citations

• Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome.

  Rosemary E. Kiernan;Stéphane Emiliani;Keiko Nakayama;Anna Castro

  129
  Citations

• The proteolysis-dependent metaphase to anaphase transition: calcium/calmodulin-dependent protein kinase II mediates onset of anaphase in extracts prepared from unfertilized Xenopus eggs.

  N Morin;A Abrieu;T Lorca;F Martin

  124
  Citations

• Greatwall is essential to prevent mitotic collapse after nuclear envelope breakdown in mammals

  Mónica Álvarez-Fernández;Ruth Sánchez-Martínez;Belén Sanz-Castillo;Pei Pei Gan

  118
  Citations

• The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A.

  Anna Castro;Suzanne Vigneron;Cyril Bernis;Jean-Claude Labbé

  114
  Citations

• Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry.

  Suzanne Vigneron;Lena Sundermann;Jean-Claude Labbé;Lionel Pintard

  101
  Citations