D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Microbiology D-index 50 Citations 11,589 120 World Ranking 2069 National Ranking 853

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Immune system
  • Cancer

Her primary scientific interests are in Cell biology, T cell, CD28, Immunology and Cytotoxic T cell. Her biological study spans a wide range of topics, including Interleukin 2, Receptor, IL-2 receptor and Immune tolerance. She is involved in the study of T cell that focuses on T-cell receptor in particular.

Her CD28 research incorporates themes from Ex vivo, CD86, Immunosuppression, CD80 and Antigen presentation. In Immunology, Vassiliki A. Boussiotis works on issues like In vivo, which are connected to Tuberculosis, Mycobacterium tuberculosis, Interferon gamma, Interleukin 10 and In vitro. Her work is dedicated to discovering how Cytotoxic T cell, Molecular biology are connected with FYN, CRKL, Semaphorin, CD72 and Germinal center and other disciplines.

Her most cited work include:

  • PD-L2 is a second ligand for PD-1 and inhibits T cell activation (2108 citations)
  • Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation (906 citations)
  • B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4 (550 citations)

What are the main themes of her work throughout her whole career to date?

Vassiliki A. Boussiotis spends much of her time researching Cell biology, T cell, Immunology, Immune system and Cancer research. Her research in Cell biology intersects with topics in Receptor, Jurkat cells and T-cell receptor. Vassiliki A. Boussiotis has researched T cell in several fields, including Cytotoxic T cell and Cell cycle.

The concepts of her Immunology study are interwoven with issues in Hematopoietic stem cell transplantation, Stem cell and Transplantation. Her studies deal with areas such as Transcription factor, B cell and Effector as well as Immune system. The Cancer research study which covers Immunotherapy that intersects with Tumor microenvironment.

She most often published in these fields:

  • Cell biology (45.45%)
  • T cell (41.61%)
  • Immunology (34.97%)

What were the highlights of her more recent work (between 2014-2021)?

  • Cell biology (45.45%)
  • T cell (41.61%)
  • Cancer research (20.98%)

In recent papers she was focusing on the following fields of study:

Her main research concerns Cell biology, T cell, Cancer research, Immune system and Immunology. Vassiliki A. Boussiotis studies Cell biology, focusing on Rap1 in particular. Her T cell research is multidisciplinary, incorporating perspectives in Cytotoxic T cell, Anaerobic glycolysis and Effector.

Her Cancer research study integrates concerns from other disciplines, such as Cancer immunotherapy, Immunotherapy and Myelopoiesis. The study incorporates disciplines such as Receptor, Signal transduction, Antigen and Lymphocyte in addition to Immune system. Vassiliki A. Boussiotis has included themes like After treatment and Hematopoietic stem cell transplantation, Transplantation in her Immunology study.

Between 2014 and 2021, her most popular works were:

  • Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway (495 citations)
  • PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation. (439 citations)
  • The PD1:PD-L1/2 Pathway from Discovery to Clinical Implementation. (204 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cancer

Her primary areas of investigation include T cell, Cell biology, Immune system, Immunotherapy and Cancer immunotherapy. Her work deals with themes such as Tyrosine, Anaerobic glycolysis, Phosphorylation, Lipid metabolism and Effector, which intersect with T cell. Her Cell biology study which covers Acquired immune system that intersects with IL-2 receptor, Antigen-presenting cell, Central tolerance, ZAP70 and Cytotoxic T cell.

Vassiliki A. Boussiotis interconnects Cell, Receptor, Signal transduction, Vaccination and Leukemia in the investigation of issues within Immune system. Her Signal transduction research is multidisciplinary, relying on both Neoplasms therapy, Cell cycle checkpoint, Computational biology and T-cell receptor. Her Cancer immunotherapy study incorporates themes from Peripheral tolerance, Neuroscience, Function and Molecular targets.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

Yvette Latchman;Clive R. Wood;Tatyana Chernova;Divya Chaudhary.
Nature Immunology (2001)

2801 Citations

Cloning of B7-2: A CTLA-4 counter-receptor that costimulates human T cell proliferation

Gordon J. Freeman;John G. Gribben;Vassiliki A. Boussiotis;Judy W. Ng.
Science (1993)

1189 Citations

B7-1 and B7-2 do not deliver identical costimulatory signals, since B7-2 but not B7-1 preferentially costimulates the initial production of IL-4

Gordon J. Freeman;Vassiliki A. Boussiotis;Anukanth Anumanthan;Gregory M. Bernstein.
Immunity (1995)

699 Citations

Molecular and Biochemical Aspects of the PD-1 Checkpoint Pathway

Vassiliki A. Boussiotis.
The New England Journal of Medicine (2016)

658 Citations

PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation.

Nikolaos Patsoukis;Kankana Bardhan;Pranam Chatterjee;Duygu Sari.
Nature Communications (2015)

556 Citations

CTLA-4 regulates induction of anergy in vivo.

Rebecca J. Greenwald;Vassiliki A. Boussiotis;Robert B. Lorsbach;Abul K. Abbas.
Immunity (2001)

554 Citations

Mouse Inducible Costimulatory Molecule (ICOS) Expression Is Enhanced by CD28 Costimulation and Regulates Differentiation of CD4+ T Cells

Alexander J. McAdam;Alexander J. McAdam;Tammy T. Chang;Anna E. Lumelsky;Edward A. Greenfield.
Journal of Immunology (2000)

544 Citations

Transplantation of anergic histoincompatible bone marrow allografts.

Eva C. Guinan;Vassiliki A. Boussiotis;Donna Neuberg;Lisa LaVita Brennan.
The New England Journal of Medicine (1999)

536 Citations

IL-10–producing T cells suppress immune responses in anergic tuberculosis patients

Vassiliki A. Boussiotis;Eunice Y. Tsai;Edmond J. Yunis;Sok Thim.
Journal of Clinical Investigation (2000)

528 Citations

Maintenance of Human T Cell Anergy: Blocking of IL-2 Gene Transcription by Activated Rap1

Vassiliki A. Boussiotis;Gordon J. Freeman;Alla Berezovskaya;Dwayne L. Barber.
Science (1997)

508 Citations

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