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Immunology

D-Index
50
Citations
7294
World Ranking
4278
National Ranking
1946

Overview

John W. Greiner is affiliated with the National Institutes of Health in the United States. Their research spans several interconnected fields, primarily focusing on immunology and oncology with multiple contributions to immunotherapy and immune response studies.

Their recent publications include the following works:

  • The Development of Next-generation PBMC Humanized Mice for Preclinical Investigation of Cancer Immunotherapeutic Agents, 2020, Anticancer Research
  • NHS-IL12, a Tumor-Targeting Immunocytokine, 2021, ImmunoTargets and Therapy
  • The Use of a Humanized NSG-β2m−/− Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa, 2020, Frontiers in Oncology
  • Aging modulates the immunosuppressive, polarizing and metabolic functions of blood-derived myeloid-derived suppressor cells (MDSCs), 2025, Immunity & Ageing
  • 1136 Vaccine targeting of the tumor-associated antigen brachyury reduces development of colitis-induced colorectal lesions in the APCMin/+mouse model, 2023, Regular and Young Investigator Award Abstracts

The research topics covered in these papers reflect a focus on the following areas:

  • CAR-T cell therapy research
  • Immunotherapy and Immune Responses
  • Immune Cell Function and Interaction
  • Cancer Immunotherapy and Biomarkers
  • Virus-based gene therapy research
  • Immune cells in cancer
  • Immune Response and Inflammation

John W. Greiner's work predominantly falls within immunology and microbiology, with notable contributions to medicine. Their research is further detailed by involvement in subfields such as immunology, oncology, genetics, pathology and forensic medicine, and biotechnology.

The scientist has collaborated frequently with several co-authors, including Jeffrey Schlom, Y. Maurice Morillon, Ariana Sabzevari, Lucas A. Horn, and Claudia Palena. These collaborations have contributed to a breadth of published research across multiple venues.

Publication venues where John W. Greiner's work has appeared include:

  • Anticancer Research
  • ImmunoTargets and Therapy
  • Frontiers in Oncology
  • Immunity & Ageing
  • Regular and Young Investigator Award Abstracts

Best Publications

  • Chitosan solution enhances both humoral and cell-mediated immune responses to subcutaneous vaccination.

    David A. Zaharoff;Connie J. Rogers;Kenneth W. Hance;Jeffrey Schlom

  • Generation and Characterization of B72.3 Second Generation Monoclonal Antibodies Reactive with the Tumor-associated Glycoprotein 72 Antigen

    R Muraro;M Kuroki;D Wunderlich;D J Poole

  • Enhanced expression of surface tumor-associated antigens on human breast and colon tumor cells after recombinant human leukocyte α-interferon treatment

    John W. Greiner;Patricia Horan Hand;Philip Noguchi;Paul B. Fisher

  • Recombinant interferon enhances monoclonal antibody-targeting of carcinoma lesions in vivo

    John W. Greiner;Fiorella Guadagni;Philip Noguchi;Sidney Pestka

  • Physical activity and cancer prevention : pathways and targets for intervention.

    Connie J. Rogers;Lisa H. Colbert;John W. Greiner;Susan N. Perkins

  • Induction of Protective Host Immunity to Carcinoembryonic Antigen (CEA), a Self-Antigen in CEA Transgenic Mice, by Immunizing with a Recombinant Vaccinia-CEA Virus

    Erik Kass;Jeffrey Schlom;John Thompson;Fiorella Guadagni

  • An NK cell line (haNK) expressing high levels of granzyme and engineered to express the high affinity CD16 allele.

    Caroline Jochems;James W. Hodge;Massimo Fantini;Rika Fujii

  • The immunocytokine NHS-IL12 as a potential cancer therapeutic

    Jonathan Fallon;Robert Tighe;Giorgio Kradjian;Wilson Guzman

  • Granulocyte/macrophage-colony stimulating factor produced by recombinant avian poxviruses enriches the regional lymph nodes with antigen-presenting cells and acts as an immunoadjuvant

    Erik Kass;Dennis L. Panicali;Gail Mazzara;Jeffrey Schlom

  • Vaccine-based therapy directed against carcinoembryonic antigen demonstrates antitumor activity on spontaneous intestinal tumors in the absence of autoimmunity.

    John W Greiner;Hasan Zeytin;Miriam R Anver;Jeffrey Schlom

  • Immunogenicity and safety of a recombinant vaccinia virus vaccine expressing the carcinoembryonic antigen gene in a nonhuman primate.

    J. Kantor;K. Irvine;S. Abrams;P. Snoy

  • Intravesical Immunotherapy of Superficial Bladder Cancer with Chitosan/Interleukin-12

    David A. Zaharoff;Benjamin S. Hoffman;H. Brooks Hooper;Compton J. Benjamin

  • Regulation of Carcinoembryonic Antigen Expression in Different Human Colorectal Tumor Cells by Interferon-γ

    Fiorella Guadagni;Patricia L. Witt;Paul F. Robbins;Jeffrey Schlom

  • Vaccination with a recombinant Saccharomyces cerevisiae expressing a tumor antigen breaks immune tolerance and elicits therapeutic antitumor responses.

    Elizabeth K. Wansley;Mala Chakraborty;Kenneth W. Hance;Michael B. Bernstein

  • Intratumoral immunotherapy of established solid tumors with chitosan/IL-12.

    David A. Zaharoff;Kenneth W. Hance;Connie J. Rogers;Jeffrey Schlom

  • Selective Interferon-Induced Enhancement of Tumor-Associated Antigens on a Spectrum of Freshly Isolated Human Adenocarcinoma Cells

    Fiorella Guadagni;Jeffrey Schlom;William W. Johnston;Cheryl A. Szpak

  • Systemic Immunotherapy of Non-Muscle Invasive Mouse Bladder Cancer with Avelumab, an Anti–PD-L1 Immune Checkpoint Inhibitor

    Amanda J. Vandeveer;Jonathan K. Fallon;Robert Tighe;Helen Sabzevari

  • Improved Immunotherapy of a Recombinant Carcinoembryonic Antigen Vaccinia Vaccine When Given in Combination with Interleukin-2

    Joanne P. McLaughlin;Jeffrey Schlom;Judy A. Kantor;John W. Greiner

  • CA 72-4 measurement of tumor-associated glycoprotein 72 (TAG-72) as a serum marker in the management of gastric carcinoma

    Fiorella Guadagni;Mario Roselli;Teresa Amato;Maurizio Cosimelli

  • Detection of blood-borne cells in colorectal cancer patients by nested reverse transcription-polymerase chain reaction for carcinoembryonic antigen messenger RNA : Longitudinal analyses and demonstration of its potential importance as an adjunct to multiple serum markers

    Fiorella Guadagni;Judith Kantor;Simona Aloe;Maria Daniela Carone

Frequent Co-Authors

Jeffrey Schlom
Jeffrey Schlom National Institutes of Health
Stephen D. Hursting
Stephen D. Hursting University of North Carolina at Chapel Hill
James W. Hodge
James W. Hodge National Institutes of Health
Kwong Y. Tsang
Kwong Y. Tsang National Institutes of Health
Sidney Pestka
Sidney Pestka Rutgers, The State University of New Jersey
James L. Gulley
James L. Gulley National Institutes of Health
Paul B. Fisher
Paul B. Fisher Virginia Commonwealth University
Ernest C. Borden
Ernest C. Borden Cleveland Clinic
Philip M. Arlen
Philip M. Arlen National Institutes of Health
David Goldstein
David Goldstein University of New South Wales

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