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Neuroscience

D-Index
52
Citations
9842
World Ranking
5327
National Ranking
27

Overview

Insop Shim is affiliated with Kyung Hee University in South Korea. Their research spans primarily in the fields of Neuroscience and Medicine, contributing to an understanding of various neurobiological processes and disorders.

The scientist has published extensively on topics related to brain function and pathology, with a particular focus on neuroinflammation, neurodegeneration, and behavioral neuroscience. Notable research themes include Tryptophan and brain disorders, Stress Responses and Cortisol, Sleep and Wakefulness Research, Neuroinflammation and Neurodegeneration Mechanisms, Sleep and related disorders, Neuroscience and Neuropharmacology Research, and Cholinesterase and Neurodegenerative Diseases.

Frequent publication venues for their work include:

  • Journal of Exercise Rehabilitation
  • International Journal of Molecular Sciences
  • Current Issues in Molecular Biology
  • Molecular Psychiatry
  • Biomedicine & Pharmacotherapy

Regular co-authors have been:

  • Minsook Ye
  • Hyun-Jung Park
  • Sung Ja Rhie
  • Hyun Soo Shim

Some recent publications by Insop Shim are:

  • "Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson's Disease," 2020, published in Current Biology
  • "Pre/post-natal exposure to microplastic as a potential risk factor for autism spectrum disorder," 2022, published in Environment International
  • "The role of neuroinflammation on pathogenesis of affective disorders," 2020, published in Journal of Exercise Rehabilitation
  • "Protective Effects of Quercetin on Anxiety-Like Symptoms and Neuroinflammation Induced by Lipopolysaccharide in Rats," 2020, published in Evidence-based Complementary and Alternative Medicine
  • "Inhibitory effect of carvacrol on lipopolysaccharide-induced memory impairment in rats," 2020, published in Korean Journal of Physiology and Pharmacology

The research contributions cover a combination of experimental studies on neurobiological mechanisms, neuropharmacological interventions, and investigations into environmental factors affecting neurological health.

Best Publications

  • GABA from reactive astrocytes impairs memory in mouse models of Alzheimer's disease

    Seonmi Jo;Seonmi Jo;Oleg Yarishkin;Yu Jin Hwang;Ye Eun Chun

  • Stress and Sleep Disorder

    Kuem Sun Han;Lin Kim;Insop Shim

  • Effect of Crude Saponin of Korean Red Ginseng on High-Fat Diet-Induced Obesity in the Rat

    Ji Hyun Kim;Dae Hyun Hahm;Deck Chun Yang;Jang Hyun Kim

  • Neuroprotective effects of CD4 + CD25 + Foxp3 + regulatory T cells in a 3xTg-AD Alzheimer’s disease model

    Hyunjung Baek;Minsook Ye;Geun-Hyung Kang;Chanju Lee

  • Antidepressant-like effect of Salvia sclarea is explained by modulation of dopamine activities in rats.

    Geun Hee Seol;Hyun Soo Shim;Hyun Soo Shim;Pill Joo Kim;Hea Kyung Moon

  • CD4+CD25+ Regulatory T Cell Depletion Modulates Anxiety and Depression-Like Behaviors in Mice

    Soo-Jeong Kim;Hyojung Lee;Gihyun Lee;Sei-Joong Oh

  • Effects of acupuncture on chronic corticosterone-induced depression-like behavior and expression of neuropeptide Y in the rats.

    Bombi Lee;Insop Shim;Hye-Jung Lee;Young Yang

  • Nicotine-induced behavioral sensitization is associated with extracellular dopamine release and expression of c-Fos in the striatum and nucleus accumbens of the rat.

    Insop Shim;Javaid I. Javaid;David Wirtshafter;Soo Yong Jang

  • Aberrant Tonic Inhibition of Dopaminergic Neuronal Activity Causes Motor Symptoms in Animal Models of Parkinson’s Disease

    Jun Young Heo;Jun Young Heo;Min Ho Nam;Min Ho Nam;Hyung Ho Yoon;Jeongyeon Kim

  • Hypolipidemic effects of crude extract of adlay seed (Coix lachrymajobi var. mayuen) in obesity rat fed high fat diet : Relations of TNF-α and leptin mRNA expressions and serum lipid levels

    Sung Ok Kim;Su-Jin Yun;Bomi Jung;Eunjoo H. Lee

  • Phellodendron amurense and Its Major Alkaloid Compound, Berberine Ameliorates Scopolamine-Induced Neuronal Impairment and Memory Dysfunction in Rats

    Bombi Lee;Bongjun Sur;Insop Shim;Hyejung Lee

  • Expression of neuropeptide Y and cholecystokinin in the rat brain by chronic mild stress.

    Hyunyoung Kim;Wei Whan Whang;Hyun Taek Kim;Kwang Ho Pyun

  • Inhibitory Basal Ganglia Inputs Induce Excitatory Motor Signals in the Thalamus

    Jeongjin Kim;Youngsoo Kim;Ryuichi Nakajima;Anna Shin

  • Effect of acupuncture on anxiety-like behavior during nicotine withdrawal and relevant mechanisms.

    Younbyoung Chae;Mijung Yeom;Ji-Hee Han;Hi-Joon Park

  • The role of neuroinflammation on pathogenesis of affective disorders.

    Sung Ja Rhie;Eun-Yee Jung;Insop Shim

  • Ginsenoside Rg3 Alleviates Lipopolysaccharide-Induced Learning and Memory Impairments by Anti-Inflammatory Activity in Rats

    Bom Bi Lee;Bong Jun Sur;Jin Hee Park;Sung Hun Kim

  • Acupuncture-mediated inhibition of ethanol-induced dopamine release in the rat nucleus accumbens through the GABAB receptor.

    Seong Shoon Yoon;Young Kyu Kwon;Mi Ryeo Kim;Insop Shim

  • Control of motor coordination by astrocytic tonic GABA release through modulation of excitation/inhibition balance in cerebellum

    Junsung Woo;Junsung Woo;Joo Ok Min;Dae-Si Kang;Yoo Sung Kim

  • Acupuncture enhances the synaptic dopamine availability to improve motor function in a mouse model of Parkinson's disease.

    Seung-Nam Kim;Ah-Reum Doo;Ji-Yeun Park;Hyungjin Bae

  • Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease

    Minsook Ye;Hwan-Suck Chung;Chanju Lee;Moon Sik Yoon

  • Effect of electroacupuncture on response to immobilization stress.

    Chae H Yang;B.B Lee;H.S Jung;I Shim

  • Role of nitric oxide synthase inhibitors and NMDA receptor antagonist in nicotine-induced behavioral sensitization in the rat

    Insop Shim;Hyun-Taek Kim;Young-Ho Kim;Boe-Gwun Chun

  • Acupuncture normalizes the release of accumbal dopamine during the withdrawal period and after the ethanol challenge in chronic ethanol-treated rats.

    Rong Jie Zhao;Seong Shoon Yoon;Bong Hyo Lee;Young Kyu Kwon

  • Comparison of the antiobesity effects of the protopanaxadiol- and protopanaxatriol-type saponins of red ginseng.

    Ji Hyun Kim;Soon Ah Kang;Seung-Moo Han;Insop Shim

Frequent Co-Authors

C. Justin Lee
C. Justin Lee Institute for Basic Science
Hoon Ryu
Hoon Ryu Korea Institute of Science and Technology
Daesoo Kim
Daesoo Kim Korea Advanced Institute of Science and Technology
Choon-Gon Jang
Choon-Gon Jang Sungkyunkwan University
David Wirtshafter
David Wirtshafter University of Illinois at Chicago
Junghee Lee
Junghee Lee University of California, Los Angeles
Yong Chul Bae
Yong Chul Bae Kyungpook National University

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