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John P. Neoptolemos

John P. Neoptolemos

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Medicine
Germany
2026

D-Index & Metrics

Medicine

D-Index
140
Citations
90740
World Ranking
1668
National Ranking
83

Research.com Recognitions

  • 2026 - Research.com Medicine in Germany Leader Award
  • 2023 - Research.com Medicine in Germany Leader Award
  • 2019 - Member of Academia Europaea
  • Fellow of The Academy of Medical Sciences, United Kingdom
  • Fellow of The Academy of Medical Sciences, United Kingdom

Overview

John P. Neoptolemos is affiliated with Heidelberg University in Germany and has a research focus primarily in medicine, with significant contributions to biochemistry, genetics, and molecular biology.

Their recent publications cover important topics in oncology and surgery, especially related to pancreatic cancer and pancreatitis. Notable papers include:

  • Neoadjuvant therapy for pancreatic cancer, 2023, Nature Reviews Clinical Oncology
  • Immediate surgery compared with short-course neoadjuvant gemcitabine plus capecitabine, FOLFIRINOX, or chemoradiotherapy in patients with borderline resectable pancreatic cancer (ESPAC5): a four-arm, multicentre, randomised, phase 2 trial, 2022, The Lancet. Gastroenterology & Hepatology
  • A Simple Classification of Pancreatic Duct Size and Texture Predicts Postoperative Pancreatic Fistula, 2021, Annals of Surgery
  • ESPAC-5F: Four-arm, prospective, multicenter, international randomized phase II trial of immediate surgery compared with neoadjuvant gemcitabine plus capecitabine (GEMCAP) or FOLFIRINOX or chemoradiotherapy (CRT) in patients with borderline resectable pancreatic cancer., 2020, Journal of Clinical Oncology
  • Postpancreatectomy Acute Pancreatitis (PPAP), 2021, Annals of Surgery

Their co-authorship network includes frequent collaboration with Thilo Hackert, Markus W. Büchler, Christoph Springfeld, Christopher Halloran, and Jakob R. Izbicki.

Neoptolemos's work is commonly published in specific venues such as:

  • Pancreatology
  • Surgery
  • Annals of Surgery
  • Journal of Clinical Oncology
  • International Journal of Cancer

Their research fields encompass Medicine and Biochemistry, Genetics and Molecular Biology, with subfields focusing on Oncology, Surgery, Cancer Research, Molecular Biology, and Pulmonary and Respiratory Medicine.

The main topics covered in their publications include:

  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Cancer Genomics and Diagnostics
  • Epigenetics and DNA Methylation
  • Renal Cell Carcinoma Treatment
  • Neuroendocrine Tumor Research Advances
  • Gastrointestinal Disorders and Treatments

John P. Neoptolemos has been recognized with professional distinctions such as becoming a Member of Academia Europaea in 2019 and a Fellow of The Academy of Medical Sciences, United Kingdom.

Best Publications

  • Postoperative pancreatic fistula: an international study group (ISGPF) definition.

    Claudio Bassi;Christos Dervenis;Giovanni Butturini;Abe Fingerhut

  • The 2016 update of the International Study Group (ISGPS) definition and grading of postoperative pancreatic fistula : 11 Years After

    Claudio Bassi;Giovanni Marchegiani;Christos Dervenis;Micheal Sarr

  • A Randomized Trial of Chemoradiotherapy and Chemotherapy after Resection of Pancreatic Cancer

    John P. Neoptolemos;Deborah D. Stocken;Helmut Friess;Claudio Bassi

  • Delayed gastric emptying (DGE) after pancreatic surgery: A suggested definition by the International Study Group of Pancreatic Surgery (ISGPS)

    Moritz N. Wente;Claudio Bassi;Christos Dervenis;Abe Fingerhut

  • Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition.

    Moritz N. Wente;Johannes A. Veit;Claudio Bassi;Christos Dervenis

  • Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial

    John P. Neoptolemos;John P. Neoptolemos;Daniel H. Palmer;Daniel H. Palmer;Paula Ghaneh;Eftychia E. Psarelli

  • Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial

    John P. Neoptolemos;Deborah D. Stocken;Claudio Bassi;Paula Ghaneh

  • IAP Guidelines for the Surgical Management of Acute Pancreatitis

    Waldemar Uhl;Andrew Warshaw;Clement Imrie;Claudio Bassi

  • Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial.

    J. P. Neoptolemos;Janet A. Dunn;D. D. Stocken;J. Almond

  • Controlled trial of urgent endoscopic retrograde cholangiopancreatography and endoscopic sphincterotomy versus conservative treatment for acute pancreatitis due to gallstones.

    J.P. Neoptolemos;N.J. London;D. James;D.L. Carr-Locke

  • European evidence-based guidelines on pancreatic cystic neoplasms

    Marco Del Chiaro;Marc G. Besselink;Lianne Scholten;Marco J. Bruno

  • Capecitabine compared with observation in resected biliary tract cancer (BILCAP): a randomised, controlled, multicentre, phase 3 study.

    John N Primrose;Richard P Fox;Daniel H Palmer;Hassan Z Malik

  • Phase III Randomized Comparison of Gemcitabine Versus Gemcitabine Plus Capecitabine in Patients With Advanced Pancreatic Cancer

    David Cunningham;Ian Chau;Deborah D. Stocken;Juan W. Valle

  • Therapeutic developments in pancreatic cancer: current and future perspectives.

    John P. Neoptolemos;Jörg Kleeff;Jörg Kleeff;Patrick Michl;Eithne Costello

  • Borderline resectable pancreatic cancer: a consensus statement by the International Study Group of Pancreatic Surgery (ISGPS).

    Maximilian Bockhorn;Faik G. Uzunoglu;Mustapha Adham;Clem Imrie

  • Inflammatory mediators in acute pancreatitis.

    Madhav Bhatia;Mark Brady;Sheila Shokuhi;Stephen Christmas

  • Influence of resection margins on survival for patients with pancreatic cancer treated by adjuvant chemoradiation and/or chemotherapy in the ESPAC-1 randomized controlled trial.

    John P. Neoptolemos;Deborah D. Stocken;Janet A. Dunn;Jennifer Almond

  • Clinical and genetic characteristics of hereditary pancreatitis in Europe

    Nathan Howes;Markus M. Lerch;William Greenhalf;Deborah D. Stocken

  • Optimizing the outcomes of pancreatic cancer surgery

    Oliver Strobel;John Neoptolemos;Dirk Jäger;Markus W Büchler

  • SPINK1/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis.

    Roland H. Pfützer;M.Michael Barmada;Andrew P.J. Brunskill;Robert Finch

Frequent Co-Authors

Markus W. Büchler
Markus W. Büchler Champalimaud Foundation
Robert Sutton
Robert Sutton University of Liverpool
Claudio Bassi
Claudio Bassi University of Verona
Thilo Hackert
Thilo Hackert Heidelberg University
Markus M. Lerch
Markus M. Lerch Greifswald University Hospital
Oliver Strobel
Oliver Strobel Heidelberg University
David Cunningham
David Cunningham Royal Marsden NHS Foundation Trust
Federico Canzian
Federico Canzian German Cancer Research Center
Juan W. Valle
Juan W. Valle University of Manchester
David L. Carr-Locke
David L. Carr-Locke NewYork–Presbyterian Hospital

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