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Barry J. Goldstein

Barry J. Goldstein

D-Index & Metrics

Medicine

D-Index
81
Citations
31845
World Ranking
16441
National Ranking
8268

Research.com Recognitions

  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Barry J. Goldstein is affiliated with MSD in the United States and has a research profile focusing primarily on medicine with notable contributions in biochemistry, genetics, and molecular biology. Their main fields of study include endocrinology, diabetes, and metabolism, molecular biology, epidemiology, physiology, and neurology.

The research work of Barry J. Goldstein emphasizes diabetes and its related complications, with several publications addressing cardiovascular risks, metabolism, diabetes treatment, and diabetes management. Other major topics include liver disease diagnosis and treatment as well as retinal diseases and treatments.

Frequent publication venues for this researcher include Diabetes Care, Diabetes, JAMA Ophthalmology, and BMC Nutrition. Most of their works have appeared in Diabetes Care, reflecting a strong focus on diabetes-related clinical research.

Selected recent papers illustrate the scope and depth of their research:

  • Effect of Metformin and Lifestyle Interventions on Mortality in the Diabetes Prevention Program and Diabetes Prevention Program Outcomes Study (2021, Diabetes Care)
  • The Impact of Physical Activity on the Prevention of Type 2 Diabetes: Evidence and Lessons Learned From the Diabetes Prevention Program, a Long-Standing Clinical Trial Incorporating Subjective and Objective Activity Measures (2020, Diabetes Care)
  • Risk Factors for the Development of Retinopathy in Prediabetes and Type 2 Diabetes: The Diabetes Prevention Program Experience (2022, Diabetes Care)
  • Association of Metformin With the Development of Age-Related Macular Degeneration (2022, JAMA Ophthalmology)
  • Identification of Genetic Variation Influencing Metformin Response in a Multiancestry Genome-Wide Association Study in the Diabetes Prevention Program (DPP) (2022, Diabetes)

Collaborations are an important aspect of this researcher's career. Frequent co-authors include Dana Dabelea, Ronald Goldberg, Helen P. Hazuda, Kishore M. Gadde, and Kevin Furlong.

This scientist is a member of the Association of American Physicians, which reflects recognition by a professional medical association.

Best Publications

  • Type 2 diabetes - principles of pathogenesis and therapy

    Michael Stumvoll;Barry J Goldstein;Timon W van Haeften

  • Human Epicardial Adipose Tissue Is a Source of Inflammatory Mediators

    Tomasz Mazurek;LiFeng Zhang;Andrew Zalewski;John D. Mannion

  • Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein.

    Xiao Jian Sun;P. Rothenberg;P. Rothenberg;C. R. Kahn;J. M. Backer

  • Adiponectin: A novel adipokine linking adipocytes and vascular function.

    Barry J. Goldstein;Rosario Scalia

  • Adiponectin regulates albuminuria and podocyte function in mice

    Kumar Sharma;Satish RamachandraRao;Gang Qiu;Hitomi Kataoka Usui

  • Insulin resistance as the core defect in type 2 diabetes mellitus

    Barry J Goldstein

  • Effect of Initial Combination Therapy With Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, and Metformin on Glycemic Control in Patients With Type 2 Diabetes

    Barry J. Goldstein;Mark N. Feinglos;Jared K. Lunceford;Jeremy Johnson

  • AMPK and cell proliferation – AMPK as a therapeutic target for atherosclerosis and cancer

    Hiroyuki Motoshima;Barry J. Goldstein;Motoyuki Igata;Eiichi Araki

  • The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

    Kalyankar Mahadev;Hiroyuki Motoshima;Xiangdong Wu;Jean Marie Ruddy

  • Involvement of AMP-activated protein kinase in glucose uptake stimulated by the globular domain of adiponectin in primary rat adipocytes

    Xiangdong Wu;Hiroyuki Motoshima;Kalyankar Mahadev;Timothy J. Stalker

  • Insulin-stimulated Hydrogen Peroxide Reversibly Inhibits Protein-tyrosine Phosphatase 1B in Vivo and Enhances the Early Insulin Action Cascade

    Kalyankar Mahadev;Assaf Zilbering;Li Zhu;Barry J. Goldstein

  • Differential regulation of adiponectin secretion from cultured human omental and subcutaneous adipocytes: effects of insulin and rosiglitazone.

    Hiroyuki Motoshima;Xiangdong Wu;Madhur K. Sinha;V. Elise Hardy

  • Tyrosine Dephosphorylation and Deactivation of Insulin Receptor Substrate-1 by Protein-tyrosine Phosphatase 1B POSSIBLE FACILITATION BY THE FORMATION OF A TERNARY COMPLEX WITH THE GRB2 ADAPTOR PROTEIN

    Barry J. Goldstein;Anna Bittner-Kowalczyk;Morris F. White;Mark Harbeck

  • Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress

    Ling Tao;Erhe Gao;Xiangying Jiao;Yuexing Yuan

  • Adiponectin suppresses proliferation and superoxide generation and enhances eNOS activity in endothelial cells treated with oxidized LDL.

    Hiroyuki Motoshima;Xiangdong Wu;Kalyankar Mahadev;Barry J Goldstein

  • Redox Paradox: Insulin Action Is Facilitated by Insulin-Stimulated Reactive Oxygen Species With Multiple Potential Signaling Targets

    Barry J. Goldstein;Kalyankar Mahadev;Xiangdong Wu

  • The prevalence of retinopathy in impaired glucose tolerance and recent-onset diabetes in the Diabetes Prevention Program.

    D. M. Nathan;D. M. Nathan;E. Chew;C. A. Christophi;M. D. Davis

  • Alterations in skeletal muscle protein-tyrosine phosphatase activity and expression in insulin-resistant human obesity and diabetes.

    F Ahmad;J L Azevedo;R Cortright;G L Dohm

  • Textbook of diabetes

    Richard I. G. Holt;Clive S. Cockram;Allan Flyvbjerg;Barry J. Goldstein

  • Protective vascular and myocardial effects of adiponectin.

    Barry J Goldstein;Rosario G Scalia;Xin L Ma

Frequent Co-Authors

Michael J. Davies
Michael J. Davies University of Copenhagen
Jose C. Florez
Jose C. Florez Harvard University
Kumar Sharma
Kumar Sharma The University of Texas Health Science Center at San Antonio
Robert R. Henry
Robert R. Henry University of California, San Diego
Robert V. Considine
Robert V. Considine Indiana University
Erhe Gao
Erhe Gao Temple University
Michael Stumvoll
Michael Stumvoll Leipzig University
George A. Bray
George A. Bray Louisiana State University
Steven E. Kahn
Steven E. Kahn University of Washington
Paul I. W. de Bakker
Paul I. W. de Bakker Vertex Pharmaceuticals (United Kingdom)

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