Gerard Drewes

Overview

Best Publications

• Functional organization of the yeast proteome by systematic analysis of protein complexes

  Anne-Claude Gavin;Markus Bösche;Roland Krause;Paola Grandi

  6097
  Citations

• Proteome survey reveals modularity of the yeast cell machinery

  Anne-Claude Gavin;Patrick Aloy;Paola Grandi;Roland Krause

  3104
  Citations

• Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

  Mark A. Dawson;Rab K. Prinjha;Antje Dittmann;George Giotopoulos

  1669
  Citations

• A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway.

  Tewis Bouwmeester;Angela Bauch;Heinz Ruffner;Pierre-Olivier Angrand

  1483
  Citations

• Tracking cancer drugs in living cells by thermal profiling of the proteome

  Mikhail M. Savitski;Friedrich B. M. Reinhard;Holger Franken;Thilo Werner

  1225
  Citations

• Quantitative chemical proteomics reveals mechanisms of action of clinical ABL kinase inhibitors

  Marcus Bantscheff;Dirk Eberhard;Yann Abraham;Sonja Bastuck

  1175
  Citations

• MARK, a Novel Family of Protein Kinases That Phosphorylate Microtubule-Associated Proteins and Trigger Microtubule Disruption

  Gerard Drewes;Andreas Ebneth;Ute Preuss;Eva-Maria Mandelkow

  1025
  Citations

• A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response

  Laurens Kruidenier;Chun-wa Chung;Zhongjun Cheng;John Liddle

  1008
  Citations

• Phosphorylation of Ser262 strongly reduces binding of tau to microtubules: Distinction between PHF-like immunoreactivity and microtubule binding

  J Biernat;N Gustke;G Drewes;E M Mandelkow

  989
  Citations

• Inhibition of PAD4 activity is sufficient to disrupt mouse and human NET formation

  Huw D Lewis;John Liddle;Jim E Coote;Stephen J Atkinson

  768
  Citations

• Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

  G Drewes;B Lichtenberg-Kraag;F Döring;E M Mandelkow

  766
  Citations

• Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

  Marcus Bantscheff;Carsten Hopf;Mikhail M Savitski;Antje Dittmann

  753
  Citations

• Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau

  E.-M. Mandelkow;G. Drewes;J. Biernat;N. Gustke

  713
  Citations

• Alzheimer-like paired helical filaments and antiparallel dimers formed from microtubule-associated protein tau in vitro.

  H Wille;G Drewes;J Biernat;E M Mandelkow

  595
  Citations

• Thermal proteome profiling for unbiased identification of direct and indirect drug targets using multiplexed quantitative mass spectrometry

  Holger Franken;Toby Mathieson;Dorothee Childs;Gavain M A Sweetman

  593
  Citations

• Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

  J Chapuis;F Hansmannel;M Gistelinck;A Mounier

  470
  Citations

• MAPs, MARKs and microtubule dynamics.

  Gerard Drewes;Andreas Ebneth;Eva-Maria Mandelkow

  438
  Citations

• Selective targeting of BD1 and BD2 of the BET proteins in cancer and immunoinflammation

  Omer Gilan;Omer Gilan;Inmaculada Rioja;Kathy Knezevic;Matthew J. Bell

  402
  Citations

• Tau domains, phosphorylation, and interactions with microtubules

  E.-M. Mandelkow;J. Biernat;G. Drewes;N. Gustke

  385
  Citations

• Microtubule-associated Protein/Microtubule Affinity-regulating Kinase (p110mark) A NOVEL PROTEIN KINASE THAT REGULATES TAU-MICROTUBULE INTERACTIONS AND DYNAMIC INSTABILITY BY PHOSPHORYLATION AT THE ALZHEIMER-SPECIFIC SITE SERINE 262

  Gerard Drewes;Bernhard Trinczek;Susanne Illenberger;Jacek Biernat

  371
  Citations