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Thomas J. Louie

Thomas J. Louie

D-Index & Metrics

Microbiology

D-Index
61
Citations
18403
World Ranking
2952
National Ranking
84

Overview

Thomas J. Louie is affiliated with the University of Calgary in Canada, focusing on research in medicine with a particular emphasis on infectious diseases. Their contributions span critical subfields including infectious diseases, molecular biology, critical care and intensive care medicine, epidemiology, and gastroenterology.

Louie's research addresses core topics such as Clostridium difficile and Clostridium perfringens infections, gut microbiota and health, nosocomial infections in intensive care units, microscopic colitis, gastrointestinal motility and disorders, Helicobacter pylori-related gastroenterology studies, and viral gastroenteritis research and epidemiology.

Frequent coauthors in Louie's work include Sahil Khanna, Lisa Von Moltke, Paul Feuerstadt, John Conly, and Darrell S. Pardi, indicating collaborative work within infectious diseases and gastroenterology research communities.

The scientist has published extensively in several key venues, with multiple publications appearing in Gastroenterology, Open Forum Infectious Diseases, The American Journal of Gastroenterology, Infection Control and Hospital Epidemiology, and JAMA.

  • Efficacy and Safety of RBX2660 in PUNCH CD3, a Phase III, Randomized, Double-Blind, Placebo-Controlled Trial with a Bayesian Primary Analysis for the Prevention of Recurrent Clostridioides difficile Infection (2022, Drugs)
  • VE303, a Defined Bacterial Consortium, for Prevention of Recurrent Clostridioides difficile Infection (2023, JAMA)
  • Metabolic independence drives gut microbial colonization and resilience in health and disease (2023, Genome Biology)
  • Safety and Tolerability of SER-109 as an Investigational Microbiome Therapeutic in Adults With Recurrent Clostridioides difficile Infection (2023, JAMA Network Open)
  • Detection and quantification of infectious severe acute respiratory coronavirus-2 in diverse clinical and environmental samples (2022, Scientific Reports)

Best Publications

  • Fidaxomicin versus Vancomycin for Clostridium difficile Infection

    Thomas J. Louie;Mark A. Miller;Kathleen M. Mullane;Karl Weiss

  • Novel Multiplex PCR Assay for Characterization and Concomitant Subtyping of Staphylococcal Cassette Chromosome mec Types I to V in Methicillin-Resistant Staphylococcus aureus

    Kunyan Zhang;Jo-Ann McClure;Sameer Elsayed;Thomas Louie

  • Treating Clostridium difficile Infection With Fecal Microbiota Transplantation

    Johan S. Bakken;Thomas Borody;Lawrence J. Brandt;Joel V. Brill

  • Emergence and global spread of epidemic healthcare-associated Clostridium difficile.

    Miao He;Fabio Miyajima;Paul Roberts;Louise Ellison

  • Effect of Oral Capsule- vs Colonoscopy-Delivered Fecal Microbiota Transplantation on Recurrent Clostridium difficile Infection: A Randomized Clinical Trial.

    Dina Kao;Brandi Roach;Marisela Silva;Paul Beck

  • Vancomycin, Metronidazole, or Tolevamer for Clostridium difficile Infection: Results From Two Multinational, Randomized, Controlled Trials

    Stuart Johnson;Thomas J. Louie;Dale N. Gerding;Oliver A. Cornely

  • A human gut bacterial genome and culture collection for improved metagenomic analyses.

    Samuel C. Forster;Samuel C. Forster;Samuel C. Forster;Nitin Kumar;Blessing O. Anonye;Blessing O. Anonye;Alexandre Almeida;Alexandre Almeida

  • New Quadriplex PCR Assay for Detection of Methicillin and Mupirocin Resistance and Simultaneous Discrimination of Staphylococcus aureus from Coagulase-Negative Staphylococci

    Kunyan Zhang;Jennifer Sparling;Barbara L. Chow;Sameer Elsayed

  • Microbial synergy in experimental intra-abdominal abscess.

    Andrew B. Onderdonk;John G. Bartlett;Thomas Louie;Nadine Sullivan-Seigler

  • Treatment of first recurrence of Clostridium difficile infection: fidaxomicin versus vancomycin.

    Oliver A. Cornely;Mark A. Miller;Thomas J. Louie;Derrick W. Crook;Derrick W. Crook

  • Novel Multiplex PCR Assay for Detection of the Staphylococcal Virulence Marker Panton-Valentine Leukocidin Genes and Simultaneous Discrimination of Methicillin-Susceptible from -Resistant Staphylococci

    Jo-Ann McClure;John M. Conly;Vicky Lau;Sameer Elsayed

  • Fidaxomicin Preserves the Intestinal Microbiome During and After Treatment of Clostridium difficile Infection (CDI) and Reduces Both Toxin Reexpression and Recurrence of CDI

    Thomas J. Louie;Kris Cannon;Brendan Byrne;Judy Emery

  • Efficacy of Fidaxomicin Versus Vancomycin as Therapy for Clostridium difficile Infection in Individuals Taking Concomitant Antibiotics for Other Concurrent Infections

    Kathleen M. Mullane;Mark A. Miller;Karl Weiss;Arnold Lentnek

  • A new macrocyclic antibiotic, fidaxomicin (OPT-80), causes less alteration to the bowel microbiota of Clostridium difficile-infected patients than does vancomycin

    Gerald W. Tannock;Karen Munro;Corinda Taylor;Blair Lawley

  • Fidaxomicin versus vancomycin for Clostridium difficile infection: meta-analysis of pivotal randomized controlled trials.

    Derrick W. Crook;Derrick W. Crook;A. Sarah Walker;A. Sarah Walker;Yin Kean;Karl Weiss

  • Aerobic and Anaerobic Bacteria in Diabetic Foot Ulcers

    Thomas J. Louie;John G. Bartlett;Francis P. Tally;Sherwood L. Gorbach

  • OPT-80 eliminates Clostridium difficile and is sparing of bacteroides species during treatment of C. difficile infection.

    Thomas J. Louie;Judy Emery;Walter Krulicki;Brendan Byrne

  • Outbreak in Alberta of community-acquired (USA300) methicillin-resistant Staphylococcus aureus in people with a history of drug use, homelessness or incarceration

    Mark Gilbert;Judy MacDonald;Dan Gregson;Jennifer Siushansian

  • Tolevamer, a Novel Nonantibiotic Polymer, Compared with Vancomycin in the Treatment of Mild to Moderately Severe Clostridium difficile–Associated Diarrhea

    Thomas J. Louie;Jennifer Peppe;C. Kevin Watt;David Johnson

  • Nosocomial Outbreak of Carbapenem-Resistant Pseudomonas aeruginosa with a New blaIMP Allele, blaIMP-7

    Alan Patrick Gibb;Chanwit Tribuddharat;Richard A. Moore;Thomas J. Louie

  • Incidence and risk factors for acquiring nosocomial urinary tract infection in the critically ill

    Kevin B. Laupland;David A. Zygun;David A. Zygun;H.Dele Davies;Deirdre L. Church;Deirdre L. Church

Frequent Co-Authors

Sherwood L. Gorbach
Sherwood L. Gorbach Tufts University
Derrick W. Crook
Derrick W. Crook University of Oxford
Oliver A. Cornely
Oliver A. Cornely University of Cologne
Dale N. Gerding
Dale N. Gerding Veterans Health Administration
Paul L. Beck
Paul L. Beck University of Calgary
Kevin B. Laupland
Kevin B. Laupland Queensland University of Technology
Mark A. Miller
Mark A. Miller University of California San Francisco Medical Center
Deirdre L. Church
Deirdre L. Church University of Calgary
Mark W. Miller
Mark W. Miller Boston University
Carl Erik Nord
Carl Erik Nord Karolinska University Hospital

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