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Biology and Biochemistry

D-Index
46
Citations
7030
World Ranking
18983
National Ranking
609

Research.com Recognitions

  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Nica Borgese is a researcher affiliated with the National Research Council (CNR) in Italy. Their work spans several fields primarily within Biochemistry, Genetics, and Molecular Biology, as well as Medicine. The main subfields of Borgese's research include Molecular Biology, Cell Biology, Neurology, Genetics, and Sensory Systems.

Their research focuses strongly on issues relating to Endoplasmic Reticulum Stress and Disease, Amyotrophic Lateral Sclerosis Research, Neurogenetic and Muscular Disorders Research, Galectins and Cancer Biology, Prion Diseases and Protein Misfolding, and Ion channel regulation and function.

Among recent publications authored or co-authored by Borgese are:

  • Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity, 2020, Proceedings of the National Academy of Sciences
  • The Link between VAPB Loss of Function and Amyotrophic Lateral Sclerosis, 2021, Cells
  • ERO1 alpha deficiency impairs angiogenesis by increasing N-glycosylation of a proangiogenic VEGFA, 2022, Redox Biology
  • Mutant VAPB: Culprit or Innocent Bystander of Amyotrophic Lateral Sclerosis?, 2021, Contact
  • Searching for remote homologs of CAML among eukaryotes, 2020, Traffic

Borgese frequently collaborates with several coauthors, including Ester Zito, Sara Colombo, Francesca Navone, Ersilia Varone, and Alexander Chernorudskiy.

Their publications have appeared in a range of venues such as Cells, Proceedings of the National Academy of Sciences, Redox Biology, Contact, and Traffic.

Borgese has been recognized as a Member of the European Molecular Biology Organization (EMBO), a membership indicating engagement with the broader molecular biology research community.

Best Publications

  • PI(4,5)P2-Dependent and Ca2+-Regulated ER-PM Interactions Mediated by the Extended Synaptotagmins

    Francesca Giordano;Francesca Giordano;Yasunori Saheki;Yasunori Saheki;Olof Idevall-Hagren;Olof Idevall-Hagren;Sara Francesca Colombo

  • Formation of stacked ER cisternae by low affinity protein interactions

    Erik L. Snapp;Ramanujan S. Hegde;Maura Francolini;Francesca Lombardo

  • The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane

    Nica Borgese;Sara Colombo;Emanuela Pedrazzini

  • Targeting pathways of C-tail-anchored proteins.

    Nica Borgese;Elisa Fasana

  • Endoplasmic reticulum architecture: structures in flux.

    Nica Borgese;Maura Francolini;Erik Snapp

  • How tails guide tail-anchored proteins to their destinations.

    Nica Borgese;Silvia Brambillasca;Sara Colombo

  • Ribosomal-membrane interaction: in vitro binding of ribosomes to microsomal membranes.

    Nica Borgese;Winnie Mok;Gert Kreibich;David D. Sabatini

  • Transmembrane topogenesis of a tail-anchored protein is modulated by membrane lipid composition

    Silvia Brambillasca;Monica Yabal;Paolo Soffientini;Sandra Stefanovic

  • Unassisted translocation of large polypeptide domains across phospholipid bilayers

    Silvia Brambillasca;Monica Yabal;Marja Makarow;Nica Borgese

  • Uncovering Common Principles in Protein Export of Malaria Parasites

    Christof Grüring;Arlett Heiber;Florian Kruse;Sven Flemming

  • Targeting of a Tail-anchored Protein to Endoplasmic Reticulum and Mitochondrial Outer Membrane by Independent but Competing Pathways

    Nica Borgese;Ilaria Gazzoni;Massimo Barberi;Sara Colombo

  • KDEL and KKXX Retrieval Signals Appended to the Same Reporter Protein Determine Different Trafficking between Endoplasmic Reticulum, Intermediate Compartment, and Golgi Complex

    Mariano Stornaiuolo;Lavinia V. Lotti;Nica Borgese;Maria Rosaria Torrisi

  • Activation of the Endothelial Nitric-oxide Synthase by Tumor Necrosis Factor-α A NOVEL FEEDBACK MECHANISM REGULATING CELL DEATH

    Stefania Bulotta;Rico Barsacchi;Domenicantonio Rotiroti;Nica Borgese

  • Transmembrane domain-dependent partitioning of membrane proteins within the endoplasmic reticulum.

    Paolo Ronchi;Sara Colombo;Maura Francolini;Nica Borgese

  • A role for N-myristoylation in protein targeting: NADH-cytochrome b5 reductase requires myristic acid for association with outer mitochondrial but not ER membranes

    Nica Borgese;Diego Aggujaro;Paola Carrera;Grazia Pietrini

  • A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum.

    Elisa Fasana;Matteo Fossati;Annamaria Ruggiano;Silvia Brambillasca

  • Selective activation of the transcription factor ATF6 mediates endoplasmic reticulum proliferation triggered by a membrane protein

    Jessica Maiuolo;Stefania Bulotta;Claudia Verderio;Roberta Benfante

  • Activation of endothelial nitric-oxide synthase by tumor necrosis factor-alpha: a novel pathway involving sequential activation of neutral sphingomyelinase, phosphatidylinositol-3' kinase, and Akt.

    Rico Barsacchi;Cristiana Perrotta;Stefania Bulotta;Salvador Moncada

  • A mutant cytochrome b5 with a lengthened membrane anchor escapes from the endoplasmic reticulum and reaches the plasma membrane

    Emanuela Pedrazzini;Antonello Villa;Nica Borgese

  • N-myristoylation determines dual targeting of mammalian NADH-cytochrome b(5) reductase to ER and mitochondrial outer membranes by a mechanism of kinetic partitioning

    Sara Colombo;Renato Longhi;Stefano Alcaro;Francesco Ortuso

Frequent Co-Authors

Jacopo Meldolesi
Jacopo Meldolesi Vita-Salute San Raffaele University
Emilio Clementi
Emilio Clementi University of Milan
Renato Longhi
Renato Longhi National Academies of Sciences, Engineering, and Medicine
Cecilia Gotti
Cecilia Gotti National Research Council (CNR)
Francesco Clementi
Francesco Clementi University of Milan
Pietro De Camilli
Pietro De Camilli Yale University
Maria Antonietta De Matteis
Maria Antonietta De Matteis University of Naples Federico II
Antonello Villa
Antonello Villa University of Milano-Bicocca
Ramanujan S. Hegde
Ramanujan S. Hegde MRC Laboratory of Molecular Biology

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