World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
89
Citations
31118
World Ranking
2537
National Ranking
43

Research.com Recognitions

  • 1991 - Member of Academia Europaea
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Jacopo Meldolesi is affiliated with Vita-Salute San Raffaele University in Italy and has contributed extensively to the fields of Biochemistry, Genetics and Molecular Biology, as well as Neuroscience. Their research integrates molecular biology with neurological studies, reflecting a multidisciplinary approach.

Their work covers a range of subfields including Molecular Biology, Cancer Research, Cellular and Molecular Neuroscience, Genetics, and Neurology. The main topics they have focused on include extracellular vesicles in disease, microRNA in disease regulation, mesenchymal stem cell research, RNA interference and gene delivery, RNA regulation and disease, Alzheimer's disease research and treatments, and neuroinflammation and neurodegeneration mechanisms.

Some of the recent publications by Jacopo Meldolesi include:

  • Alternative Splicing by NOVA Factors: From Gene Expression to Cell Physiology and Pathology, 2020, International Journal of Molecular Sciences
  • Extracellular Vesicles of Mesenchymal Stem Cells: Therapeutic Properties Discovered with Extraordinary Success, 2021, Biomedicines
  • Extracellular vesicles (exosomes and ectosomes) play key roles in the pathology of brain diseases, 2021, Molecular Biomedicine
  • Unconventional Protein Secretion Dependent on Two Extracellular Vesicles: Exosomes and Ectosomes, 2022, Frontiers in Cell and Developmental Biology
  • Autism Spectrum Disorder: Brain Areas Involved, Neurobiological Mechanisms, Diagnoses and Therapies, 2024, International Journal of Molecular Sciences

Jacopo Meldolesi has published multiple articles in notable journals such as Biomedicines, International Journal of Molecular Sciences, Molecular Biomedicine, Journal of Experimental Pathology, and Frontiers in Cell and Developmental Biology.

The scientist frequently collaborates with researchers including Gabriella Racchetti and Jacopo Lamanna.

In recognition of their contributions, Jacopo Meldolesi is a member of Academia Europaea (since 1991) and the European Molecular Biology Organization (EMBO).

Best Publications

  • Shedding microvesicles: artefacts no more

    Emanuele Cocucci;Gabriella Racchetti;Jacopo Meldolesi

  • Molecular and cellular physiology of intracellular calcium stores

    T. Pozzan;R. Rizzuto;P. Volpe;J. Meldolesi

  • Ectosomes and exosomes: shedding the confusion between extracellular vesicles

    Emanuele Cocucci;Emanuele Cocucci;Jacopo Meldolesi

  • CXCR4-activated astrocyte glutamate release via TNFalpha: amplification by microglia triggers neurotoxicity.

    Paola Bezzi;Maria Domercq;Liliana Brambilla;Rossella Galli

  • Exosomes and Ectosomes in Intercellular Communication

    Jacopo Meldolesi

  • 'Calciosome', a cytoplasmic organelle: The inositol 1,4,5-trisphosphate-sensitive Ca2+ store of nonmuscle cells?

    Pompeo Volpe;Karl-Heinz Krause;Sadamitsu Hashimoto;Francesco Zorzato

  • Inositol 1,4,5-trisphosphate receptor localized to endoplasmic reticulum in cerebellar Purkinje neurons.

    Christopher A. Ross;Jacopo Meldolesi;Teresa A. Milner;Tomohide Satoh

  • Neurotransmitter release: fusion or 'kiss-and-run'?

    Riccardo Fesce;Fabio Grohovaz;Flavia Valtorta;Jacopo Meldolesi

  • The inositol 1,4,5,-trisphosphate receptor in cerebellar Purkinje cells: quantitative immunogold labeling reveals concentration in an ER subcompartment.

    Tomohide Satoh;Christopher A. Ross;Antonello Villa;Surachai Supattapone

  • BiP, a major chaperone protein of the endoplasmic reticulum lumen, plays a direct and important role in the storage of the rapidly exchanging pool of Ca2+

    Jean Philippe Lièvremont;Rosario Rizzuto;Linda Hendershot;Jacopo Meldolesi

  • Supramaximal caerulein stimulation and ultrastructure of rat pancreatic acinar cell: early morphological changes during development of experimental pancreatitis

    O. Watanabe;F. M. Baccino;M. L. Steer;J. Meldolesi

  • Differential coupling of dopaminergic D2 receptors expressed in different cell types. Stimulation of phosphatidylinositol 4,5-bisphosphate hydrolysis in LtK- fibroblasts, hyperpolarization, and cytosolic-free Ca2+ concentration decrease in GH4C1 cells.

    Lucia Vallar;Claudia Muca;Michele Magni;Paul Albert

  • Activation of a muscarinic receptor selectively inhibits a rapidly inactivated Ca2+ current in rat sympathetic neurons

    E Wanke;A Ferroni;A Malgaroli;A Ambrosini

  • Composition of cellular membranes in the pancreas of the guinea pig. I. Isolation of membrane fractions.

    J. Meldolesi;J. D. Jamieson;G. E. Palade

  • Macropinocytosis: regulated coordination of endocytic and exocytic membrane traffic events

    Sestina Falcone;Emanuele Cocucci;Paola Podini;Tomas Kirchhausen

  • Control of cytosolic free calcium in rat and chicken osteoclasts. The role of extracellular calcium and calcitonin.

    A Malgaroli;J Meldolesi;A Z Zallone;A Teti

  • The Cell Biology of Experimental Pancreatitis

    Michael L. Steer;Jacopo Meldolesi

  • Pathways of Ca2+ influx at the plasma membrane: Voltage-, receptor-, and second messenger-operated channels

    Jacopo Meldolesi;Tullio Pozzan

  • Ca++-dependent disassembly and reassembly of occluding junctions in guinea pig pancreatic acinar cells. Effect of drugs.

    J Meldolesi;G Castiglioni;R Parma;N Nassivera

  • The Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases

    Pietro Baldelli;Jacopo Meldolesi

Frequent Co-Authors

Tullio Pozzan
Tullio Pozzan University of Padua
Pompeo Volpe
Pompeo Volpe University of Padua
Emilio Clementi
Emilio Clementi University of Milan
Nica Borgese
Nica Borgese National Research Council (CNR)
Atanasio Pandiella
Atanasio Pandiella Spanish National Research Council
Michael L. Steer
Michael L. Steer Harvard University
Flavia Valtorta
Flavia Valtorta Vita-Salute San Raffaele University
Andrea Volterra
Andrea Volterra University of Lausanne
Antonello Villa
Antonello Villa University of Milano-Bicocca
Daniel Pablo Lew
Daniel Pablo Lew University of Geneva

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