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Biology and Biochemistry

D-Index
62
Citations
17919
World Ranking
10608
National Ranking
4607

Overview

Leonid V. Chernomordik is affiliated with the National Institutes of Health in the United States. Their research focuses primarily on the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a significant emphasis on Molecular Biology, Oncology, Rheumatology, Cell Biology, and Nutrition and Dietetics.

The scientist's work extensively covers topics related to Bone Metabolism and Diseases, Bone Health and Treatments, Bone Tumor Diagnosis and Treatments, Trace Elements in Health, Cell Death Mechanisms and Regulation, Lipid Membrane Structure and Behavior, and Cellular Mechanics and Interactions.

Frequent collaborators in Chernomordik's research include Jarred M. Whitlock, Evgenia Leikina, Kamran Melikov, Luis F de Castro, and Michael T. Collins.

Chernomordik has contributed to several recent papers, including:

  • Flagging fusion: Phosphatidylserine signaling in cell-cell fusion (2021), Journal of Biological Chemistry
  • Myomerger promotes fusion pore by elastic coupling between proximal membrane leaflets and hemifusion diaphragm (2021), Nature Communications
  • Cell surface-bound La protein regulates the cell fusion stage of osteoclastogenesis (2023), Nature Communications
  • Novel Majeed Syndrome-Causing LPIN2 Mutations Link Bone Inflammation to Inflammatory M2 Macrophages and Accelerated Osteoclastogenesis (2020), Arthritis & Rheumatology
  • Phosphatidylserine orchestrates Myomerger membrane insertions to drive myoblast fusion (2022), Proceedings of the National Academy of Sciences

The primary publication venues where Chernomordik's work appears include bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, eLife, Biophysical Journal, and Journal of Biological Chemistry.

Best Publications

  • Mechanics of membrane fusion.

    Leonid V Chernomordik;Michael M Kozlov

  • Protein-lipid interplay in fusion and fission of biological membranes.

    Leonid V Chernomordik;Michael M Kozlov

  • Cellular Uptake of Unconjugated TAT Peptide Involves Clathrin-dependent Endocytosis and Heparan Sulfate Receptors

    Jean Philippe Richard;Kamran Melikov;Hilary Brooks;Paul Prevot

  • Lipids in biological membrane fusion.

    L. Chernomordik;M. M. Kozlov;J. Zimmerberg

  • Membrane Hemifusion: Crossing a Chasm in Two Leaps

    Leonid V. Chernomordik;Michael M. Kozlov

  • The pathway of membrane fusion catalyzed by influenza hemagglutinin: restriction of lipids, hemifusion, and lipidic fusion pore formation.

    Leonid V. Chernomordik;Vadim A. Frolov;Eugenia Leikina;Peter Bronk

  • Voltage-induced nonconductive pre-pores and metastable single pores in unmodified planar lipid bilayer.

    Kamran C. Melikov;Kamran C. Melikov;Vadim A. Frolov;Arseniy Shcherbakov;Andrey V. Samsonov

  • Carbohydrate-binding molecules inhibit viral fusion and entry by crosslinking membrane glycoproteins

    Eugenia Leikina;Helene Delanoe-Ayari;Kamran Melikov;Myoung-Soon Cho

  • Lipid Intermediates in Membrane Fusion: Formation, Structure, and Decay of Hemifusion Diaphragm

    Yonathan Kozlovsky;Leonid V. Chernomordik;Michael M. Kozlov

  • Dengue virus ensures its fusion in late endosomes using compartment-specific lipids.

    Elena Zaitseva;Sung-Tae Yang;Kamran Melikov;Sergei Pourmal

  • Non-bilayer lipids and biological fusion intermediates.

    Leonid Chernomordik

  • An Early Stage of Membrane Fusion Mediated by the Low pH Conformation of Influenza Hemagglutinin Depends upon Membrane Lipids

    Leonid V. Chernomordik;Eugenia Leikina;Vadim Frolov;Peter Bronk

  • The hemifusion intermediate and its conversion to complete fusion: regulation by membrane composition.

    L. Chernomordik;A. Chanturiya;J. Green;J. Zimmerberg

  • Protein-driven membrane stresses in fusion and fission

    Michael M. Kozlov;Harvey T. McMahon;Leonid V. Chernomordik

  • Membranes of the world unite

    Leonid V. Chernomordik;Joshua Zimmerberg;Michael M. Kozlov

  • Flickering fusion pores comparable with initial exocytotic pores occur in protein-free phospholipid bilayers

    Alexandr Chanturiya;Leonid V. Chernomordik;Joshua Zimmerberg

  • Mechanisms of Membrane Fusion

    J Zimmerberg;S S Vogel;L V Chernomordik

  • Mechanisms shaping cell membranes

    Michael M Kozlov;Felix Campelo;Nicole Liska;Leonid V Chernomordik

  • Lysolipids reversibly inhibit Ca2+‐, GTP‐ and pH‐dependent fusion of biological membranes

    Leonid V. Chernomordik;Steven S. Vogel;Aleksander Sokoloff;H.Ongun Onaran

  • A Mechanism of Protein-Mediated Fusion: Coupling between Refolding of the Influenza Hemagglutinin and Lipid Rearrangements

    Michael M. Kozlov;Leonid V. Chernomordik

Frequent Co-Authors

Michael M. Kozlov
Michael M. Kozlov Tel Aviv University
Joshua Zimmerberg
Joshua Zimmerberg National Institutes of Health
Richard M. Epand
Richard M. Epand McMaster University
Harvey T. McMahon
Harvey T. McMahon MRC Laboratory of Molecular Biology
Leonid Margolis
Leonid Margolis National Institutes of Health
Félix A. Rey
Félix A. Rey Institut Pasteur
Robert I. Lehrer
Robert I. Lehrer University of California, Los Angeles
Benjamin J. Doranz
Benjamin J. Doranz University of Pennsylvania
Diane E. Griffin
Diane E. Griffin Johns Hopkins University
Kenneth H. Fischbeck
Kenneth H. Fischbeck National Institutes of Health

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