Jean-François Gauchat mainly investigates Molecular biology, Immunoglobulin E, Interleukin 4, T cell and CD40. The various areas that Jean-François Gauchat examines in his Molecular biology study include Antigen, Messenger RNA, Exon, CD23 and COS cells. Jean-François Gauchat combines subjects such as Cytokine and Interleukin 10 with his study of Immunoglobulin E.
His studies deal with areas such as Peripheral blood mononuclear cell and Immunoglobulin class switching as well as Interleukin 4. He focuses mostly in the field of Immunoglobulin class switching, narrowing it down to matters related to B-cell proliferation and, in some cases, Cell biology. His T cell study combines topics in areas such as Cytotoxic T cell, T lymphocyte and B cell.
Jean-François Gauchat spends much of his time researching Molecular biology, Immunology, Cell biology, Cytokine and Immunoglobulin E. His Molecular biology research is multidisciplinary, incorporating perspectives in CD40, T cell, Antigen, B cell and Glycoprotein 130. His work in Immunology covers topics such as In vitro which are related to areas like Pharmacology.
Jean-François Gauchat interconnects Proinflammatory cytokine, Receptor, Cell growth and Antigen-presenting cell in the investigation of issues within Cell biology. Jean-François Gauchat has researched Cytokine in several fields, including Protein subunit, Ciliary neurotrophic factor and CD19. His Immunoglobulin E research is multidisciplinary, relying on both Immunoglobulin class switching, Isotype and Interleukin 4.
The scientist’s investigation covers issues in Cytokine, Cell biology, Immunology, CLCF1 and Receptor. His Cytokine research incorporates themes from Cancer research, Ciliary neurotrophic factor and Bone marrow. His study in Cell biology is interdisciplinary in nature, drawing from both Interleukin 21, IL-2 receptor and Antigen-presenting cell.
His research integrates issues of Defensin and Bacterial protein in his study of Immunology. His CLCF1 research is multidisciplinary, incorporating perspectives in Myeloid and Janus kinase 2. His research in Receptor is mostly focused on Cytokine receptor.
Jean-François Gauchat mainly focuses on Cytokine, Immunology, Internal medicine, Endocrinology and Cell biology. The Cytokine study combines topics in areas such as Plasma cell differentiation, Receptor, Interferon type I and Immunopathology. His work in the fields of Internal medicine, such as Renal cortex, Creatinine and Albuminuria, overlaps with other areas such as Cell morphology.
His work is dedicated to discovering how Endocrinology, Janus kinase 2 are connected with Glycoprotein 130 and Janus kinase and other disciplines. His Glycoprotein 130 study combines topics from a wide range of disciplines, such as Cancer research, Leukemia inhibitory factor receptor and Ciliary neurotrophic factor. His work carried out in the field of Cell biology brings together such families of science as Plasma cell, Regulatory T cell differentiation and Cell growth.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Involvement of LOX-1 in dendritic cell-mediated antigen cross-presentation
Yves Delneste;Giovanni Magistrelli;Jean-François Gauchat;Jean-François Haeuw.
IgE Versus IgG4 Production Can Be Differentially Regulated by IL-10
Pascale Jeannin;Sybille Lecoanet;Yves Delneste;Jean-François Gauchat.
Journal of Immunology (1998)
Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.
J F Gauchat;D A Lebman;R L Coffman;H Gascan.
Journal of Experimental Medicine (1990)
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.
H Gascan;J F Gauchat;M G Roncarolo;H Yssel.
Journal of Experimental Medicine (1991)
Direct bacterial protein PAMP recognition by human NK cells involves TLRs and triggers α-defensin production
Anick Chalifour;Pascale Jeannin;Jean-François Gauchat;Aline Blaecke.
Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways.
H Gascan;J F Gauchat;G Aversa;P Van Vlasselaer.
Journal of Immunology (1991)
A soluble form of CTLA-4 generated by alternative splicing is expressed by nonstimulated human T cells.
Giovanni Magistrelli;Pascale Jeannin;Nathalie Herbault;Amélie Benoit de Coignac.
European Journal of Immunology (1999)
CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex.
G C Elson;E Lelièvre;C Guillet;S Chevalier.
Nature Neuroscience (2000)
IL-10 and viral IL-10 prevent IL-4-induced IgE synthesis by inhibiting the accessory cell function of monocytes.
J Punnonen;R de Waal Malefyt;P van Vlasselaer;J F Gauchat.
Journal of Immunology (1993)
Human CD40-ligand: molecular cloning, cellular distribution and regulation of expression by factors controlling IgE production.
Jean-François Gauchat;Jean-Pierre Aubry;Gonzalo Mazzei;Paul Life.
FEBS Letters (1993)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: