Hugues Gascan

Overview

Best Publications

• Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

  Jérôme Pène;Sylvie Chevalier;Laurence Preisser;Emilie Véneréau

  728
  Citations

• The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

  Sébastien Jaillon;Giuseppe Peri;Yves Delneste;Isabelle Frémaux

  654
  Citations

• Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells.

  Dorothée Duluc;Dorothée Duluc;Yves Delneste;Yves Delneste;Fang Tan;Fang Tan;Marie-Pierre Moles

  597
  Citations

• Binding of the Drosophila cytokine Spätzle to Toll is direct and establishes signaling

  Alexander N.R. Weber;Servane Tauszig-Delamasure;Jules A. Hoffmann;Eric Lelièvre

  533
  Citations

• Direct Stimulation of Human T Cells via TLR5 and TLR7/8: Flagellin and R-848 Up-Regulate Proliferation and IFN-γ Production by Memory CD4 + T Cells

  Gersende Caron;Dorothée Duluc;Isabelle Frémaux;Pascale Jeannin

  528
  Citations

• Induction of osteogenesis in mesenchymal stem cells by activated monocytes/macrophages depends on Oncostatin M signaling

  P. Guihard;P. Guihard;Y. Danger;B. Brounais;B. Brounais;E. David;E. David

  510
  Citations

• Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.

  H Gascan;J F Gauchat;M G Roncarolo;H Yssel

  471
  Citations

• Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production.

  J F Gauchat;D A Lebman;R L Coffman;H Gascan

  446
  Citations

• Released form of CNTF receptor alpha component as a soluble mediator of CNTF responses

  Samuel Davis;Thomas H. Aldrich;Nancy Y. Ip;Neil Stahl

  437
  Citations

• Anti-CD40 monoclonal antibodies or CD4+ T cell clones and IL-4 induce IgG4 and IgE switching in purified human B cells via different signaling pathways.

  H Gascan;J F Gauchat;G Aversa;P Van Vlasselaer

  397
  Citations

• Neutrophils efficiently cross-prime naive T cells in vivo

  Céline Beauvillain;Yves Delneste;Mari Scotet;Audrey Peres

  391
  Citations

• CLF associates with CLC to form a functional heteromeric ligand for the CNTF receptor complex.

  G C Elson;E Lelièvre;C Guillet;S Chevalier

  356
  Citations

• Interleukin-33 overexpression is associated with liver fibrosis in mice and humans.

  Pierrick Marvie;Mariette Lisbonne;Annie L’Helgoualc’h;Michel Rauch

  302
  Citations

• Oncostatin M Secreted by Skin Infiltrating T Lymphocytes Is a Potent Keratinocyte Activator Involved in Skin Inflammation

  Katia Boniface;Caroline Diveu;Caroline Diveu;Franck Morel;Nathalie Pedretti

  229
  Citations

• Functional interaction of STAT3 transcription factor with the cell cycle inhibitor p21WAF1/CIP1/SDI1.

  Olivier Coqueret;Hugues Gascan

  224
  Citations

• Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor

  Damien Derouet;François Rousseau;Fabienne Alfonsi;Josy Froger

  214
  Citations

• Signaling of the Cardiotrophin-1 Receptor EVIDENCE FOR A THIRD RECEPTOR COMPONENT

  Olivier Robledo;Maryvonne Fourcin;Sylvie Chevalier;Catherine Guillet

  171
  Citations

• Modulation of IL-4 induced germline ε RNA synthesis in human B cells by tumor necrosis factor-α, anti-CD40 monoclonal antibodies or transforming growth factor-β correlates with levels of IgE production

  J F Gauchat;G Aversa;H Gascan;J E de Vries

  171
  Citations

• Signaling of Type II Oncostatin M Receptor

  Patrick Auguste;Catherine Guillet;Maryvonne Fourcin;Christophe Olivier

  161
  Citations

• Cyclin D1 Represses STAT3 Activation through a Cdk4-independent Mechanism *

  Frédéric Bienvenu;Hugues Gascan;Olivier Coqueret

  161
  Citations