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Irma A. J. M. Bakker-Woudenberg

Irma A. J. M. Bakker-Woudenberg

D-Index & Metrics

Microbiology

D-Index
51
Citations
6753
World Ranking
4377
National Ranking
163

Overview

Irma A. J. M. Bakker-Woudenberg is affiliated with Erasmus MC in the Netherlands. Their research primarily spans the fields of Medicine, Immunology and Microbiology, and Biochemistry, Genetics and Molecular Biology, with particular focus on several specialized subfields.

The subfields associated with Bakker-Woudenberg's work include Microbiology, Pulmonary and Respiratory Medicine, Pharmaceutical Science, Molecular Medicine, and Pharmacology. This interdisciplinary approach aligns with the scientist's interest in topics related to drug delivery mechanisms, antimicrobial activity, and bacterial resistance.

Key topics covered in their research consist of:

  • Antimicrobial Peptides and Activities
  • Inhalation and Respiratory Drug Delivery
  • Advanced Drug Delivery Systems
  • Antibiotic Resistance in Bacteria
  • Antibiotics Pharmacokinetics and Efficacy
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Biochemical and Structural Characterization

Their publication record includes research articles in peer-reviewed journals such as Antimicrobial Agents and Chemotherapy, Antibiotics, and Scientific Reports. Examples of recent papers authored or coauthored by Bakker-Woudenberg are:

  • "Therapeutic Efficacy of Novel Antimicrobial Peptide AA139-Nanomedicines in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia-Septicemia Model in Rats," 2020, Antimicrobial Agents and Chemotherapy
  • "Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia-Septicemia Model in Rats," 2020, Antibiotics
  • "Differential binding of human and murine IgGs to catalytic and cell wall binding domains of Staphylococcus aureus peptidoglycan hydrolases," 2021, Scientific Reports

Frequent collaborators include Hessel van der Weide, Marian T. ten Kate, Aart van der Meijden, Denise M. C. Vermeulen-de Jongh, and Wil H. F. Goessens, all of whom have coauthored at least two papers with Bakker-Woudenberg.

Best Publications

  • Liposome-encapsulated aminoglycosides in pre-clinical and clinical studies

    Raymond Schiffelers;Gert Storm;Irma Bakker-Woudenberg

  • Time–kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis

    Jurriaan E M de Steenwinkel;Gerjo J de Knegt;Marian T ten Kate;Alex van Belkum

  • Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages

    Toos Daemen;Gert Hofstede;Marian T. Ten Kate;Irma A. J. M. Bakker-Woudenberg

  • Clinical use of liposomal and lipid-complexed amphotericin B

    S. De Marie;R. Janknegt;I. A. J. M. Bakker-Woudenberg

  • Liposomes with Prolonged Blood Circulation and Selective Localization in Klebsiella pneumoniae-Infected Lung Tissue

    I. A. J. M. Bakker-Woudenberg;August F. Lokerse;M. T. ten Kate;J. W. Mouton

  • Quantitative Galactomannan Detection Is Superior to PCR in Diagnosing and Monitoring Invasive Pulmonary Aspergillosis in an Experimental Rat Model

    Martin J. Becker;Siem de Marie;Diana Willemse;Henri A. Verbrugh

  • Therapeutic efficacy of continuous versus intermittent administration of ceftazidime in an experimental Klebsiella pneumoniae pneumonia in rats.

    Robert Roosendaal;I. A. J. M. Bakker-Woudenberg;J. C. van den Berg;M. F. Michel

  • Management of mycetoma: major challenge in tropical mycoses with limited international recognition.

    Abdalla A O Ahmed;Wendy W J van de Sande;Ahmed Fahal;Irma Bakker-Woudenberg

  • Continuous versus intermittent administration of ceftazidime in experimental Klebsiella pneumoniae pneumonia in normal and leukopenic rats.

    R Roosendaal;I A Bakker-Woudenberg;M van den Berghe-van Raffe;M F Michel

  • Drug susceptibility of mycobacterium tuberculosis Beijing genotype and association with MDR TB

    Jurriaan E.M. de Steenwinkel;Marian T. ten Kate;Gerjo J. de Knegt;Kristin Kremer

  • Enhanced localization of liposomes with prolonged blood circulation time in infected lung tissue

    Irma A.J.M. Bakker-Woudenberg;August F. Lokerse;Marian T. ten Kate;Gert Storm

  • Biodistribution of liposomal amphotericin B (AmBisome) and amphotericin B-desoxycholate (Fungizone) in uninfected immunocompetent mice and leucopenic mice infected with Candida albicans

    Els W. M. van Etten;Marièe Otte-Lambillion;Wim van Vianen;Marian T. ten Kate

  • Efficacy of Gentamicin or Ceftazidime Entrapped in Liposomes with Prolonged Blood Circulation and Enhanced Localization in Klebsiella pneumoniae-Infected Lung Tissue

    Irma A. J. M. Bakker-Woudenberg;M. T. ten Kate;L. E. T. Stearne-Cullen;M. C. Woodle

  • Optimization of the Rifampin Dosage to Improve the Therapeutic Efficacy in Tuberculosis Treatment Using a Murine Model

    Jurriaan E. M. de Steenwinkel;Rob E. Aarnoutse;Gerjo J. de Knegt;Marian T. ten Kate

  • Liposomal amphotericin B (AmBisome) reduces dissemination of infection as compared with amphotericin B deoxycholate (Fungizone) in a rate model of pulmonary aspergillosis.

    A. C. A. P. Leenders;S. de Marie;M. T. ten Kate;I. A. J. M. Bakker-Woudenberg

  • In Vitro Susceptibilities of Madurella mycetomatis to Itraconazole and Amphotericin B Assessed by a Modified NCCLS Method and a Viability-Based 2,3-Bis(2-Methoxy-4-Nitro-5- Sulfophenyl)-5-[(Phenylamino)Carbonyl]-2H- Tetrazolium Hydroxide (XTT) Assay

    Abdalla O. A. Ahmed;Wendy W. J. van de Sande;Wim van Vianen;Alex van Belkum

  • Free Versus Liposome-Entrapped Ampicillin in Treatment of Infection Due to Listeria monocytogenes in Normal and Athymic (Nude) Mice

    Irma A. J. M. Bakker-Woudenberg;A. F. Lokerse;F. H. Roerdink;D. Regts

  • Apolipoprotein CI stimulates the response to lipopolysaccharide and reduces mortality in Gram-negative sepsis

    Jimmy F. P. Berbée;Caroline C. van der Hoogt;Robert Kleemann;Emile F. Schippers

  • Testing of the In Vitro Susceptibilities of Madurella mycetomatis to Six Antifungal Agents by Using the Sensititre System in Comparison with a Viability-Based 2,3-Bis(2-Methoxy-4-Nitro-5-Sulfophenyl)-5- [(Phenylamino)Carbonyl]-2H-Tetrazolium Hydroxide (XTT) Assay and a Modified NCCLS Method

    Wendy W. J. van de Sande;Ad Luijendijk;Abdalla O. A. Ahmed;Irma A. J. M. Bakker-Woudenberg

  • Impact of the Dosage Schedule on the Efficacy of Ceftazidime, Gentamicin and Ciprofloxacin in Klebsiella Pneumoniae Pneumonia and Septicemia in Leukopenic Rats

    Roosendaal R;Bakker-Woudenberg Ia;van den Berghe-van Raffe M;Vink-van den Berg Jc

  • Efficacies of amphotericin B-desoxycholate (Fungizone), liposomal amphotericin B (AmBisome) and fluconazole in the treatment of systemic candidosis in immunocompetent and leucopenic mice

    Els W. M. van Etten;Cora van den Heuvel-de Groot;Irma A. J. M. Bakker-Woudenberg

Frequent Co-Authors

Gert Storm
Gert Storm Utrecht University
Henri A. Verbrugh
Henri A. Verbrugh Erasmus University Rotterdam
Raymond M. Schiffelers
Raymond M. Schiffelers Utrecht University
Alex van Belkum
Alex van Belkum BaseClear B.V.
Johan W. Mouton
Johan W. Mouton Radboud University Medical Center
Dick van Soolingen
Dick van Soolingen National Institute for Public Health and the Environment
Girbe Buist
Girbe Buist University Medical Center Groningen
Pieter J. M. Leenen
Pieter J. M. Leenen Erasmus University Rotterdam
Jan Maarten van Dijl
Jan Maarten van Dijl University Medical Center Groningen
Gerrit L. Scherphof
Gerrit L. Scherphof University of Groningen

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