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Microbiology

D-Index
84
Citations
28021
World Ranking
912
National Ranking
49

Overview

Hans Yssel is affiliated with Sorbonne University in France and works primarily in the field of Medicine. Their research encompasses several subfields including Infectious Diseases, Rheumatology, Immunology, Public Health, Environmental and Occupational Health, as well as Cardiology and Cardiovascular Medicine.

Their recent scholarly output highlights a focus on viral infections, immunological responses, and systemic autoimmune diseases, frequently intersecting with COVID-19 research. Key topics in their body of work include COVID-19 Clinical Research Studies, SARS-CoV-2 and COVID-19 Research, Systemic Lupus Erythematosus Research, Viral Infections and Immunology Research, COVID-19 epidemiological studies, Mosquito-borne diseases and control, and Viral Infections and Vectors.

Hans Yssel has contributed to the following recent papers:

  • IgA dominates the early neutralizing antibody response to SARS-CoV-2, 2020, Science Translational Medicine
  • Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine, 2020, Annals of the Rheumatic Diseases
  • IgA dominates the early neutralizing antibody response to SARS-CoV-2, 2020, bioRxiv (Cold Spring Harbor Laboratory)
  • Lower disease activity but higher risk of severe COVID-19 and herpes zoster in patients with systemic lupus erythematosus with pre-existing autoantibodies neutralising IFN-α, 2022, Annals of the Rheumatic Diseases
  • Distinct cytokine profiles associated with COVID-19 severity and mortality, 2021, Journal of Allergy and Clinical Immunology

Frequent co-authors collaborating with Hans Yssel include:

  • Karim Dorgham
  • Guy Gorochov
  • Alexis Mathian
  • Christophe Parizot
  • Zahir Amoura

Their work has appeared in several notable publication venues, such as:

  • Annals of the Rheumatic Diseases
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Allergy and Clinical Immunology
  • Science Translational Medicine
  • Journal of the American College of Cardiology

The research contributions made by Hans Yssel largely revolve around infectious diseases with a focus on understanding immune responses and clinical progressions in COVID-19, in addition to exploring autoimmune disorders such as systemic lupus erythematosus. Their involvement in multidisciplinary topics intersects epidemiological studies, immunology, and cardiovascular complications, reflecting an integrative approach to medical research.

Best Publications

  • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression.

    R de Waal Malefyt;J Haanen;H Spits;M G Roncarolo

  • Biology of Zika Virus Infection in Human Skin Cells

    Rodolphe Hamel;Ophélie Dejarnac;Sineewanlaya Wichit;Peeraya Ekchariyawat

  • IgA dominates the early neutralizing antibody response to SARS-CoV-2.

    Delphine Sterlin;Delphine Sterlin;Alexis Mathian;Makoto Miyara;Audrey Mohr

  • Direct effects of IL-10 on subsets of human CD4+ T cell clones and resting T cells. Specific inhibition of IL-2 production and proliferation.

    R de Waal Malefyt;H Yssel;J E de Vries

  • DNAM-1, A Novel Adhesion Molecule Involved in the Cytolytic Function of T Lymphocytes

    Akira Shibuya;David Campbell;Charles Hannum;Hans Yssel

  • Chronically Inflamed Human Tissues Are Infiltrated by Highly Differentiated Th17 Lymphocytes

    Jérôme Pène;Sylvie Chevalier;Laurence Preisser;Emilie Véneréau

  • Mesenchymal Stem Cells Inhibit Human Th17 Cell Differentiation and Function and Induce a T Regulatory Cell Phenotype

    Soufiane Ghannam;Jérôme Pène;Gabriel Moquet-Torcy;Christian Jorgensen

  • Simultaneous production of IL-2, IL-4, and IFN-gamma by activated human CD4+ and CD8+ T cell clones.

    X Paliard;R de Waal Malefijt;H Yssel;D Blanchard

  • Allergen immunotherapy: therapeutic vaccines for allergic diseases

    J. Bousquet;R. Lockey;H.J. Malling;E. Alvarez-Cuesta

  • A novel receptor involved in T-cell activation.

    B. G. Cocks;C.-C. J. Chang;J. M. Carballido;H. Yssel

  • Serum-free medium for generation and propagation of functional human cytotoxic and helper T cell clones.

    H Yssel;J E De Vries;M Koken;W Van Blitterswijk

  • IL-10 is produced by subsets of human CD4+ T cell clones and peripheral blood T cells.

    H Yssel;R De Waal Malefyt;M G Roncarolo;J S Abrams

  • Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

    Ai Ing Lim;Ai Ing Lim;Ai Ing Lim;Yan Li;Yan Li;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Silvia Lopez-Lastra;Ralph Stadhouders

  • Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by interleukin 4 and a signal provided by activated CD4+ T cell clones.

    H Gascan;J F Gauchat;M G Roncarolo;H Yssel

  • Nasal mast cells in perennial allergic rhinitics exhibit increased expression of the Fc epsilonRI, CD40L, IL-4, and IL-13, and can induce IgE synthesis in B cells.

    R Pawankar;M Okuda;H Yssel;K Okumura

  • Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples.

    John S. Abrams;Maria Grazia Roncarolo;Hans Yssel;Ulf Andersson

  • Cutting edge: IL-21 is a switch factor for the production of IgG1 and IgG3 by human B cells.

    Jérôme Pène;Jean-François Gauchat;Sandrine Lécart;Elodie Drouet

  • Functional expression of B7/BB1 on activated T lymphocytes

    M Azuma;H Yssel;J H Phillips;H Spits

  • Differentiation and stability of T helper 1 and 2 cells derived from naive human neonatal CD4+ T cells, analyzed at the single-cell level.

    T Sornasse;P V Larenas;K A Davis;J E de Vries

  • Borrelia burgdorferi activates a T helper type 1-like T cell subset in Lyme arthritis.

    Hans Yssel;Marie-Claude Shanafelt;Carol Soderberg;Patricia V Schneider

  • T cell activation-inducing epitopes of the house dust mite allergen Der p I. Proliferation and lymphokine production patterns by Der p I-specific CD4+ T cell clones.

    H Yssel;K E Johnson;P V Schneider;J Wideman

Frequent Co-Authors

J E de Vries
J E de Vries AIMM Therapeutics (Netherlands)
Dorothée Missé
Dorothée Missé Institut de Recherche pour le Développement
Guy Gorochov
Guy Gorochov Sorbonne University
Frédéric Thomas
Frédéric Thomas University of Montpellier
Maria Grazia Roncarolo
Maria Grazia Roncarolo Stanford University
Zahir Amoura
Zahir Amoura Université Paris Cité
Hergen Spits
Hergen Spits University of Amsterdam
Jean Bousquet
Jean Bousquet University of Montpellier
Gary Peltz
Gary Peltz Stanford University
Hugues Gascan
Hugues Gascan Grenoble Alpes University

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