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Biology and Biochemistry

D-Index
112
Citations
46680
World Ranking
896
National Ranking
560

Research.com Recognitions

  • 2020 - Benjamin Franklin Medal, Franklin Institute
  • 2011 - Member of the National Academy of Medicine (NAM)
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2000 - Fellow of the American Academy of Arts and Sciences
  • 1996 - Member of the National Academy of Sciences
  • 1989 - Golden Brain Award, Minerva Foundation
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Jeremy Nathans is affiliated with Johns Hopkins University School of Medicine in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions in subfields including Molecular Biology, Neurology, Immunology, Radiology, Nuclear Medicine and Imaging, and Physiology.

Their work covers several main topics such as Barrier Structure and Function Studies, Glycosylation and Glycoproteins Research, Wnt/β-catenin signaling in development and cancer, Congenital heart defects research, Cancer-related gene regulation, Bacterial Infections and Vaccines, and Immune Response and Inflammation.

Jeremy Nathans has published numerous papers in various scientific venues. Frequent publication venues include Proceedings of the National Academy of Sciences, eLife, bioRxiv (Cold Spring Harbor Laboratory), Journal of Biological Chemistry, and Human Molecular Genetics.

Selected recent papers include:

  • A genome-wide view of the de-differentiation of central nervous system endothelial cells in culture (2020, eLife)
  • A mouse model for kinesin family member 11 (Kif11)-associated familial exudative vitreoretinopathy (2020, Human Molecular Genetics)
  • Signaling Pathways in Neurovascular Development (2022, Annual Review of Neuroscience)
  • Normal and Sjogren's syndrome models of the murine lacrimal gland studied at single-cell resolution (2023, Proceedings of the National Academy of Sciences)
  • The WNT7A/WNT7B/GPR124/RECK signaling module plays an essential role in mammalian limb development (2022, Development)

Frequent co-authors collaborating with Jeremy Nathans include Philip M. Smallwood, Amir Rattner, Yanshu Wang, Tao-Hsin Chang, and Sandra B. Gabelli.

Throughout their career, Jeremy Nathans has received multiple recognitions. These include being elected a Member of the National Academy of Sciences in 1996, a Fellow of the American Academy of Arts and Sciences in 2000, a Fellow of the American Association for the Advancement of Science in 2008, a Member of the National Academy of Medicine in 2011, the Benjamin Franklin Medal from the Franklin Institute in 2020, and the Golden Brain Award from the Minerva Foundation in 1989. Additionally, they are a Member of the Association of American Physicians.

Best Publications

  • Molecular genetics of human color vision: the genes encoding blue, green, and red pigments

    Jeremy Nathans;Darcy Thomas;David S. Hogness

  • A new member of the frizzled family from Drosophila functions as a Wingless receptor.

    Purnima Bhanot;Marcel Brink;Cindy Harryman Samos;Jen Chih Hsieh

  • A photoreceptor cell-specific ATP-binding transporter gene (ABCR) is mutated in recessive Stargardt macular dystrophy

    Rando Allikmets;Nanda Singh;Hui Sun;Noah F. Shroyer

  • Vascular development in the retina and inner ear: Control by Norrin and frizzled-4, a high-affinity ligand-receptor pair

    Qiang Xu;Yanshu Wang;Alain Dabdoub;Philip M Smallwood

  • A new secreted protein that binds to Wnt proteins and inhibits their activites

    Jen Chih Hsieh;Laurent Kodjabachian;Martha L. Rebbert;Amir Rattner

  • Molecular genetics of inherited variation in human color vision.

    Jeremy Nathans;Thomas P. Piantanida;Roger L. Eddy;Thomas B. Shows

  • Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin

    Jeremy Nathans;David S. Hogness

  • Apoptotic photoreceptor cell death in mouse models of retinitis pigmentosa.

    C Portera-Cailliau;C H Sung;J Nathans;R Adler

  • A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

    Amir Rattner;Jen Chih Hsieh;Philip M. Smallwood;Debra J. Gilbert

  • Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain

    Alisa Mo;Eran A. Mukamel;Eran A. Mukamel;Fred P. Davis;Chongyuan Luo

  • Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling

    Anna I. Lyuksyutova;Chin Chun Lu;Nancy Milanesio;Leslie A. King

  • Isolation and nucleotide sequence of the gene encoding human rhodopsin

    Jeremy Nathans;David S. Hogness

  • A member of the frizzled protein family mediating axis induction by Wnt- 5A

    Xi He;Jean Pierre Saint-Jeannet;Yanshu Wang;Jeremy Nathans

  • Insights into Wnt binding and signalling from the structures of two Frizzled cysteine-rich domains

    Charles E. Dann;Jen Chih Hsieh;Amir Rattner;Divya Sharma

  • The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells.

    Yanshu Wang;Nini Guo;Jeremy Nathans

  • Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa.

    Ching-Hwa Sung;Barbara G. Schneider;Neeraj Agarwal;David S. Papermaster

  • The vitelliform macular dystrophy protein defines a new family of chloride channels.

    Hui Sun;Takashi Tsunenari;King Wai Yau;Jeremy Nathans

  • Rhodopsin mutations in autosomal dominant retinitis pigmentosa.

    Ching Hwa Sung;Carol M. Davenport;Jill C. Hennessey;Irene H. Maumenee

  • Tissue/planar cell polarity in vertebrates: new insights and new questions

    Yanshu Wang;Jeremy Nathans

  • A Large Family of Putative Transmembrane Receptors Homologous to the Product of the Drosophila Tissue Polarity Gene frizzled

    Yanshu Wang;Jennifer P. Macke;Benjamin S. Abella;Katrin Andreasson

Frequent Co-Authors

Samuel G. Jacobson
Samuel G. Jacobson University of Pennsylvania
Mengqing Xiang
Mengqing Xiang Sun Yat-sen University
William H. Klein
William H. Klein The University of Texas MD Anderson Cancer Center
Neal S. Peachey
Neal S. Peachey Cleveland Clinic
Loyal A. Goff
Loyal A. Goff Johns Hopkins University School of Medicine
King Wai Yau
King Wai Yau Johns Hopkins University School of Medicine
Ryan Lister
Ryan Lister University of Western Australia
Gerald H. Jacobs
Gerald H. Jacobs University of California, Santa Barbara
Joseph R. Ecker
Joseph R. Ecker Salk Institute for Biological Studies
Joseph R. Nery
Joseph R. Nery Salk Institute for Biological Studies

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