2026 Margaret Fahnestock: Neuroscience Researcher – H-Index, Publications & Awards

Discipline name	D-Index	World Ranking	Current World Ranking	National Ranking	Current National Ranking	Publications	Citations
Neuroscience	60	3816	3490	217	196	169	14305

Overview

Margaret Fahnestock is affiliated with McMaster University in Canada. Their academic work spans multiple disciplines within medicine and neuroscience, contributing significantly to research on neurodegenerative diseases, neuroplasticity, and exercise physiology.

Their research publications focus mainly on neurophysiological and molecular mechanisms as they relate to brain function and recovery. Some of the recent papers authored include:

A Single Bout of High-intensity Interval Exercise Increases Corticospinal Excitability, Brain-derived Neurotrophic Factor, and Uncarboxylated Osteolcalcin in Sedentary, Healthy Males, 2020, Neuroscience
Understanding the Neurophysiological and Molecular Mechanisms of Exercise-Induced Neuroplasticity in Cortical and Descending Motor Pathways: Where Do We Stand?, 2020, Neuroscience
Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer's Disease, 2023, Biomolecules
Aberrant AZIN2 and polyamine metabolism precipitates tau neuropathology, 2021, Journal of Clinical Investigation
BDNF, proBDNF and IGF-1 serum levels in naïve and medicated subjects with autism, 2022, Scientific Reports

Margaret Fahnestock's frequent coauthors include:

Bernadeta Michalski
Boris Šakić
Kim Madden
Lisa C. Carlesso
Donglai Ma

Regular publication venues for their research comprise:

Osteoarthritis and Cartilage Open
bioRxiv (Cold Spring Harbor Laboratory)
Alzheimer's & Dementia
Neuroscience
Cells

The main fields of study in which Margaret Fahnestock is active involve:

Medicine
Neuroscience

Their subfields of study include:

Cellular and Molecular Neuroscience
Neurology
Physiology
Molecular Biology
Pharmacology

Key topics covered by Margaret Fahnestock's research are diverse and specialized, including:

Alzheimer's disease research and treatments
Nerve injury and regeneration
Stroke Rehabilitation and Recovery
Neuroinflammation and Neurodegeneration Mechanisms
Tryptophan and brain disorders
Nuclear Receptors and Signaling
Transcranial Magnetic Stimulation Studies

Best Publications

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut–brain communication

P. Bercik;A. J. Park;D. Sinclair;A. Khoshdel

1172
Citations
Kindling and status epilepticus models of epilepsy: rewiring the brain.

Kiyoshi Morimoto;Margaret Fahnestock;Ronald J Racine

1076
Citations
Precursor form of brain-derived neurotrophic factor and mature brain-derived neurotrophic factor are decreased in the pre-clinical stages of Alzheimer's disease.

Shiyong Peng;Joanne Wuu;Elliott J. Mufson;Margaret Fahnestock

799
Citations
The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.

Fabia Filipello;Raffaella Morini;Irene Corradini;Valerio Zerbi

691
Citations
The Precursor Pro-Nerve Growth Factor Is the Predominant Form of Nerve Growth Factor in Brain and Is Increased in Alzheimer's Disease

Margaret Fahnestock;Bernadeta Michalski;Bin Xu;Michael D. Coughlin

637
Citations
The valproic acid-induced rodent model of autism.

Chiara Nicolini;Margaret Fahnestock

565
Citations
Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer's disease

R.M.Dalmian Holsinger;Jane Schnarr;Pauline Henry;Vivian T Castelo

416
Citations
Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer’s disease

Bernadeta Michalski;Margaret Fahnestock

336
Citations
Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease

Shiyong Peng;Joanne Wuu;Elliott J. Mufson;Margaret Fahnestock

295
Citations
Oligomeric Amyloid Decreases Basal Levels of Brain-Derived Neurotrophic factor (BDNF) mRNA via Specific Downregulation of BDNF Transcripts IV and V in Differentiated Human Neuroblastoma Cells

Diego J. Garzon;Margaret Fahnestock

260
Citations
Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression.

G M MacQueen;K Ramakrishnan;S D Croll;J A Siuciak

256
Citations
Decreased brain-derived neurotrophic factor depends on amyloid aggregation state in transgenic mouse models of Alzheimer's disease

Shiyong Peng;Diego J. Garzon;Diego J. Garzon;Monica Marchese;William Klein

253
Citations
The nerve growth factor precursor proNGF exhibits neurotrophic activity but is less active than mature nerve growth factor

Margaret Fahnestock;Guanhua Yu;Bernadeta Michalski;Silvy Mathew

222
Citations
Intraventricular administration of antibodies to nerve growth factor retards kindling and blocks mossy fiber sprouting in adult rats

Ce Van der Zee;K Rashid;K Le;KA Moore

211
Citations
A new brain-derived neurotrophic factor transcript and decrease in brain-derived neurotrophic factor transcripts 1, 2 and 3 in Alzheimer's disease parietal cortex.

Diego Garzon;Guanhua Yu;Margaret Fahnestock

187
Citations
Neurotrophic factors and Alzheimer’s disease: are we focusing on the wrong molecule?

M. Fahnestock;D. Garzon;R. M. D. Holsinger;B. Michalski

186
Citations
ProNGF: a neurotrophic or an apoptotic molecule?

Margaret Fahnestock;Guanhua Yu;Michael D Coughlin

168
Citations
The effects of physical exercise and cognitive training on memory and neurotrophic factors

Jennifer J. Heisz;Ilana B. Clark;Katija Bonin;Emily M. Paolucci

165
Citations
Biological activity of nerve growth factor precursor is dependent upon relative levels of its receptors.

Raheleh Masoudi;Maria S. Ioannou;Michael D. Coughlin;Promila Pagadala

161
Citations
CREB expression mediates amyloid β-induced basal BDNF downregulation.

Elyse Rosa;Margaret Fahnestock

161
Citations
Nerve Growth Factor Accelerates Seizure Development, Enhances Mossy Fiber Sprouting, and Attenuates Seizure-Induced Decreases in Neuronal Density in the Kindling Model of Epilepsy

Beth Adams;Mona Sazgar;Philip Osehobo;Catharina E. E. M. Van der Zee

159
Citations