Ottmar Janssen

Best Publications

• Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells

  S Wesselborg;O Janssen;D Kabelitz

  488
  Citations

• Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: heterogeneous involvement of the "a disintegrin and metalloproteases" 10 and 17.

  Guranda Chitadze;Marcus Lettau;Jaydeep Bhat;Daniela Wesch

  235
  Citations

• Two-step TCRζ/CD3-CD4 and CD28 signaling in T cells: SH2/SH3 domains, protein-tyrosine and lipid kinases

  Christopher E. Rudd;Ottmar Janssen;Yun Cai Cai;Antonio J. da Silva

  234
  Citations

• Src-homology 3 domain of protein kinase p59fyn mediates binding to phosphatidylinositol 3-kinase in T cells

  Kanteti V. S. Prasad;Ottmar Janssen;Rosana Kapeller;Monika Raab

  228
  Citations

• Patterns of Chemokine Receptor Expression on Peripheral Blood γδ T Lymphocytes: Strong Expression of CCR5 Is a Selective Feature of Vδ2/Vγ9 γδ T Cells

  Andrea Glatzel;Daniela Wesch;Florian Schiemann;Ernst Brandt

  228
  Citations

• T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells.

  O Janssen;S Wesselborg;B Heckl-Ostreicher;K Pechhold

  227
  Citations

• ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death.

  M Schulte;K Reiss;M Lettau;T Maretzky

  225
  Citations

• Generation of Soluble NKG2D Ligands: Proteolytic Cleavage, Exosome Secretion and Functional Implications

  G. Chitadze;J. Bhat;M. Lettau;O. Janssen

  219
  Citations

• Staurosporine and conventional anticancer drugs induce overlapping, yet distinct pathways of apoptosis and caspase activation.

  Anna Stepczynska;Kirsten Lauber;Ingo H Engels;Ottmar Janssen

  215
  Citations

• Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage

  André Cohnen;Samuel C. Chiang;Ana Stojanovic;Hendrik Schmidt

  188
  Citations

• Phosphatidylinositol (PI) 3-kinase and PI 4-kinase binding to the CD4-p56lck complex : the p56lck SH3 domain binds to PI 3-kinase but not PI 4-kinase

  K. V S Prasad;Rosana Kapeller;Ottmar Janssen;Heinrich Repke

  182
  Citations

• The primary response of human gamma/delta + T cells to Mycobacterium tuberculosis is restricted to V gamma 9-bearing cells.

  Unknown

  176
  Citations

• Nck adapter proteins: functional versatility in T cells

  Unknown

  136
  Citations

• Nuclear Death Receptor TRAIL-R2 Inhibits Maturation of Let-7 and Promotes Proliferation of Pancreatic and Other Tumor Cells

  Verena Haselmann;Alexandra Kurz;Uwe Bertsch;Sebastian Hübner

  131
  Citations

• Secretory lysosomes and their cargo in T and NK cells

  Marcus Lettau;Hendrik Schmidt;Dieter Kabelitz;Ottmar Janssen

  124
  Citations

• Regulation of activation-induced cell death of mature T-lymphocyte populations.

  Ottmar Janssen;Ralf Sanzenbacher;Dieter Kabelitz

  120
  Citations

• Fas ligand is localized to membrane rafts, where it displays increased cell death–inducing activity

  Unknown

  110
  Citations

• Insights into the molecular regulation of FasL (CD178) biology

  Unknown

  101
  Citations

• CD95 ligand--death factor and costimulatory molecule?

  O Janssen;J Qian;A Linkermann;D Kabelitz

  95
  Citations

• Pro- and anti-apoptotic CD95 signaling in T cells

  Unknown

  93
  Citations