World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
8806
World Ranking
16299
National Ranking
511

Overview

Maria Raffaella Zocchi is affiliated with Vita-Salute San Raffaele University in Italy. Their research spans multiple interconnected areas within medicine, immunology, and molecular biology, with a strong focus on oncology and cancer-related immunotherapies.

The primary fields of study include:

  • Medicine
  • Immunology and Microbiology

More specialized subfields of their work cover:

  • Oncology
  • Immunology
  • Biomedical Engineering
  • Molecular Biology
  • Radiology, Nuclear Medicine and Imaging

Research topics addressed in their publications involve:

  • Immune Cell Function and Interaction
  • Cancer Cells and Metastasis
  • CAR-T cell therapy research
  • T-cell and B-cell Immunology
  • 3D Printing in Biomedical Research
  • Colorectal Cancer Treatments and Studies
  • Immunotherapy and Immune Responses

Zocchi has contributed to several peer-reviewed papers with a focus on immune cell roles in cancer and novel therapeutic approaches. Recent publications include the following:

  • "Natural killer cells and immune-checkpoint inhibitor therapy: Current knowledge and new challenges," 2021, Molecular Therapy - Oncolytics
  • "Physical Characterization of Colorectal Cancer Spheroids and Evaluation of NK Cell Infiltration Through a Flow-Based Analysis," 2020, Frontiers in Immunology
  • "Cancer Nanomedicine Special Issue Review Anticancer Drug Delivery with Nanoparticles: Extracellular Vesicles or Synthetic Nanobeads as Therapeutic Tools for Conventional Treatment or Immunotherapy," 2020, Cancers
  • "ADAM10 Site-Dependent Biology: Keeping Control of a Pervasive Protease," 2021, International Journal of Molecular Sciences
  • "Targeting of colorectal cancer organoids with zoledronic acid conjugated to the anti-EGFR antibody cetuximab," 2022, Journal for ImmunoTherapy of Cancer

The scientist frequently publishes in venues such as:

  • Cancers
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • Molecular Therapy - Oncolytics
  • Journal for ImmunoTherapy of Cancer

Collaborations form an integral part of their research; frequent co-authors include:

  • Alessandro Poggi
  • Roberto Benelli
  • Delfina Costa
  • Francesca Tosetti
  • Federico Villa

Best Publications

  • Unusual expression and localization of heat-shock proteins in human tumor cells.

    M Ferrarini;S Heltai;M R Zocchi;C Rugarli

  • Generation of CD4+ or CD8+ regulatory T cells upon mesenchymal stem cell-lymphocyte interaction

    Claudia Prevosto;Marta Zancolli;Paolo Canevali;Maria Raffaella Zocchi

  • The selective engulfment of apoptotic bodies by dendritic cells is mediated by the αvβ3 integrin and requires intracellular and extracellular calcium

    Anna Rubartelli;Alessandro Poggi;M. Raffaella Zocchi

  • Vδ1 T lymphocytes producing IFN-γ and IL-17 are expanded in HIV-1–infected patients and respond to Candida albicans

    Daniela Fenoglio;Alessandro Poggi;Silvia Catellani;Florinda Battaglia

  • Vδ1 T Lymphocytes from B-CLL Patients Recognize ULBP3 Expressed on Leukemic B Cells and Up-Regulated by Trans-Retinoic Acid

    Alessandro Poggi;Claudia Venturino;Silvia Catellani;Marino Clavio

  • Human γδ T cells: a nonredundant system in the immune-surveillance against cancer

    Marina Ferrarini;Elisabetta Ferrero;Lorenzo Dagna;Alessandro Poggi

  • Interaction between Human NK Cells and Bone Marrow Stromal Cells Induces NK Cell Triggering: Role of NKp30 and NKG2D Receptors

    Alessandro Poggi;Claudia Prevosto;Anna Maria Massaro;Simone Negrini

  • NK cell-mediated lysis of autologous antigen-presenting cells is triggered by the engagement of the phosphatidylinositol 3-kinase upon ligation of the natural cytotoxicity receptors NKp30 and NKp46.

    Grazia Maria Spaggiari;Roberta Carosio;Daniela Pende;Stefania Marcenaro

  • Migration of Vδ1 and Vδ2 T cells in response to CXCR3 and CXCR4 ligands in healthy donors and HIV-1-infected patients: Competition by HIV-1 Tat

    Alessandro Poggi;Roberta Carosio;Daniela Fenoglio;Sabrina Brenci

  • HIV-1 Tat: a polypeptide for all seasons

    Anna Rubartelli;Alessandro Poggi;Roberto Sitia;M.Raffaella Zocchi

  • HIV-1 Tat Inhibits Human Natural Killer Cell Function by Blocking L-Type Calcium Channels

    M R Zocchi;A Rubartelli;P Morgavi;A Poggi

  • Soluble HLA class I induces NK cell apoptosis upon the engagement of killer-activating HLA class I receptors through FasL-Fas interaction

    Grazia Maria Spaggiari;Paola Contini;Alessandra Dondero;Roberta Carosio

  • Phenotypic and functional characterization of recombinant interleukin 2 (rIL 2)-induced activated killer cells: analysis at the population and clonal levels

    S Ferrini;S Miescher;M R Zocchi;V von Fliedner

  • Roles of tumor necrosis factor p55 and p75 receptors in TNF-α-induced vascular permeability

    Elisabetta Ferrero;Maria Raffaella Zocchi;Elena Magni;Maria Carla Panzeri

  • Mechanisms of tumor escape from immune system: Role of mesenchymal stromal cells

    Alessandro Poggi;Alessandra Musso;Irene Dapino;Maria Raffaella Zocchi

  • Soluble HLA class I molecules induce natural killer cell apoptosis through the engagement of CD8: evidence for a negative regulation exerted by members of the inhibitory receptor superfamily.

    Grazia Maria Spaggiari;Paola Contini;Roberta Carosio;Marica Arvigo

  • Human Gut-Associated Natural Killer Cells in Health and Disease

    Alessandro Poggi;Roberto Benelli;Roberta Venè;Delfina Costa

  • Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate

    A Poggi;S Catellani;A Garuti;I Pierri

  • NK cell activation by dendritic cells is dependent on LFA-1-mediated induction of calcium-calmodulin kinase II: inhibition by HIV-1 Tat C-terminal domain.

    Alessandro Poggi;Roberta Carosio;Grazia Maria Spaggiari;Claudio Fortis

  • High ERp5/ADAM10 expression in lymph node microenvironment and impaired NKG2D-ligands recognition in Hodgkin lymphomas

    Maria Raffaella Zocchi;Silvia Catellani;Paolo Canevali;Sara Tavella

Frequent Co-Authors

Alessandro Poggi
Alessandro Poggi University of Modena and Reggio Emilia
Lorenzo Moretta
Lorenzo Moretta Bambino Gesù Children's Hospital
Ruggero Pardi
Ruggero Pardi Vita-Salute San Raffaele University
Roberto Benelli
Roberto Benelli University of Genoa
Anna Rubartelli
Anna Rubartelli National Cancer Research Institute, UK
Francesco Indiveri
Francesco Indiveri University of Genoa
Francesco Puppo
Francesco Puppo University of Genoa
Giuseppe Murdaca
Giuseppe Murdaca University of Genoa
Giovanna Borsellino
Giovanna Borsellino Max Delbrück Center for Molecular Medicine
Silvano Ferrini
Silvano Ferrini University of Genoa

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