Jacqueline Sagen mainly focuses on Adrenal medulla, Transplantation, Nociception, Endocrinology and Internal medicine. The Adrenal medulla study combines topics in areas such as Medullary cavity and Chronic pain. Her work deals with themes such as Neuropathic pain, Hyperalgesia, Allodynia and Opioid, which intersect with Chronic pain.
Her Transplantation research is multidisciplinary, incorporating elements of Chromaffin cell, Immune system and Opioid peptide. Jacqueline Sagen interconnects Central nervous system and Neuroscience in the investigation of issues within Nociception. In Endocrinology, she works on issues like Spinal cord, which are connected to -Naloxone.
Jacqueline Sagen mainly investigates Transplantation, Endocrinology, Internal medicine, Adrenal medulla and Nociception. -Naloxone, Morphine and Nicotine is closely connected to Opioid peptide in her research, which is encompassed under the umbrella topic of Transplantation. Her work carried out in the field of Adrenal medulla brings together such families of science as Tissue Graft, Central nervous system, Medullary cavity, Peripheral nerve injury and Spinal cord.
Her Spinal cord study combines topics from a wide range of disciplines, such as GABAergic and Anatomy. Her research integrates issues of Anesthesia, Neuropathic pain, Pharmacology and Agonist in her study of Nociception. Her Pharmacology research integrates issues from NMDA receptor, Antagonist, Chronic pain and Hyperalgesia, Allodynia.
Neuropathic pain, Pharmacology, Nociception, Anesthesia and Allodynia are her primary areas of study. The concepts of her Neuropathic pain study are interwoven with issues in Spinal cord injury, Hyperalgesia, Chronic pain and Transplantation. Her Hyperalgesia research focuses on Neuroscience and how it relates to Peripheral nerve injury, Internal medicine, Glial fibrillary acidic protein, Endocrinology and Sciatic nerve.
The Analgesic research she does as part of her general Pharmacology study is frequently linked to other disciplines of science, such as Genetic enhancement, therefore creating a link between diverse domains of science. In her study, Hemopressin and Rimonabant is inextricably linked to WIN 55,212-2, which falls within the broad field of Nociception. Her work in Anesthesia tackles topics such as Fatty acid amide hydrolase which are related to areas like Anandamide.
The scientist’s investigation covers issues in Allodynia, Pharmacology, Neuropathic pain, Hyperalgesia and Nociception. Jacqueline Sagen combines subjects such as Analgesic, Anesthesia and AM251 with her study of Allodynia. Her study explores the link between Anesthesia and topics such as Spinal cord injury that cross with problems in Glutamate receptor.
Her work in Pharmacology addresses subjects such as Cannabinoid, which are connected to disciplines such as Cannabinoid receptor, Hot plate test, Fatty acid amide hydrolase and URB597. Her studies deal with areas such as Nerve injury, Neuroscience, Conotoxin and Dorsal root ganglion as well as Hyperalgesia. Jacqueline Sagen has researched Nociception in several fields, including Agonist, WIN 55,212-2, Rimonabant, Hemopressin and Ziconotide.
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Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts.
T Ibuki;A T Hama;X T Wang;G D Pappas.
Peripheral nerve exposure to HIV viral envelope protein gp120 induces neuropathic pain and spinal gliosis.
Uri Herzberg;Jacqueline Sagen.
Journal of Neuroimmunology (2001)
Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances.
Jacqueline Sagen;Hong Wang;Patrick A. Tresco;Patrick Aebischer.
The Journal of Neuroscience (1993)
Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.
Jacqueline Sagen;Herbert K. Proudfit.
Brain Research (1984)
Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury.
Eugene S. Fu;Yan Ping Zhang;Jacqueline Sagen;Keith A. Candiotti.
Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata
Jacqueline Sagen;Herbert K. Proudfit.
Brain Research (1985)
Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model.
Jacqueline Sagen;Hong Wang;George D. Pappas.
Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity
Jacqueline Sagen;George D. Pappas;Mark J. Perlow.
Brain Research (1986)
Adrenal medullary transplants increase spinal cord cerebrospinal fluid catecholamine levels and reduce pain sensitivity.
Jacqueline Sagen;James E. Kemmler;Hong Wang.
Journal of Neurochemistry (1991)
Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord
J Sagen;G D Pappas;H B Pollard.
Proceedings of the National Academy of Sciences of the United States of America (1986)
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