Jacqueline Sagen

Overview

Best Publications

• Loss of GABA-immunoreactivity in the spinal dorsal horn of rats with peripheral nerve injury and promotion of recovery by adrenal medullary grafts.

  T Ibuki;A T Hama;X T Wang;G D Pappas

  399
  Citations

• Peripheral nerve exposure to HIV viral envelope protein gp120 induces neuropathic pain and spinal gliosis.

  Uri Herzberg;Jacqueline Sagen

  217
  Citations

• Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances.

  Jacqueline Sagen;Hong Wang;Patrick A. Tresco;Patrick Aebischer

  196
  Citations

• Effect of intrathecally administered noradrenergic antagonists on nociception in the rat.

  Jacqueline Sagen;Herbert K. Proudfit

  191
  Citations

• Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury.

  Eugene S. Fu;Yan Ping Zhang;Jacqueline Sagen;Keith A. Candiotti

  187
  Citations

• Evidence for pain modulation by pre- and postsynaptic noradrenergic receptors in the medulla oblongata

  Jacqueline Sagen;Herbert K. Proudfit

  157
  Citations

• Widespread cellular proliferation and focal neurogenesis after traumatic brain injury in the rat.

  Carlos Urrea;Daniel A Castellanos;Jacqueline Sagen;Pantelis Tsoulfas

  156
  Citations

• Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity

  Jacqueline Sagen;George D. Pappas;Mark J. Perlow

  155
  Citations

• Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model.

  Jacqueline Sagen;Hong Wang;George D. Pappas

  155
  Citations

• Adrenal medullary transplants increase spinal cord cerebrospinal fluid catecholamine levels and reduce pain sensitivity.

  Jacqueline Sagen;James E. Kemmler;Hong Wang

  145
  Citations

• Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord

  J Sagen;G D Pappas;H B Pollard

  143
  Citations

• Reduced pain-related behavior by adrenal medullary transplants in rats with experimental painful peripheral neuropathy

  Aldric T. Hama;Jacqueline Sagen

  133
  Citations

• Increased levels of Met-enkephalin-like immunoreactivity in the spinal cord CSF of rats with adrenal medullary transplants.

  Jacqueline Sagen;James E. Kemmler

  129
  Citations

• Subarachnoid Adrenal Medullary Transplants for Terminal Cancer Pain A Report of Preliminary Studies

  Alon P. Winnie;George D. Pappas;Tapas K. Das Gupta;Hong Wang

  115
  Citations

• Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats.

  P. Aebischer;P.A. Tresco;J. Sagen;S.R. Winn

  110
  Citations

• Transplantation of Encapsulated Bovine Chromaffin Cells in the Sheep Subarachnoid Space: A Preclinical Study for the Treatment of Cancer Pain:

  J.M. Joseph;M.B. Goddard;J. Mills;V. Padrun

  104
  Citations

• Human chromaffin cell graft into the CSF for cancer pain management: a prospective phase II clinical study.

  Yves Lazorthes;Jacqueline Sagen;Brigitte Sallerin;Jean Tkaczuk

  102
  Citations

• Alleviation of neuropathic pain symptoms by xenogeneic chromaffin cell grafts in the spinal subarachnoid space.

  Aldric T. Hama;Jacqueline Sagen

  95
  Citations

• TrkC overexpression enhances survival and migration of neural stem cell transplants in the rat spinal cord

  Daniel A. Castellanos;Pantelis Tsoulfas;Beata R. Frydel;Shyam Gajavelli

  93
  Citations

• Attenuation of formalin pain responses in the rat by adrenal medullary transplants in the spinal subarachnoid space.

  Julie B Siegan;Jacqueline Sagen

  87
  Citations