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Neuroscience

D-Index
47
Citations
8159
World Ranking
6452
National Ranking
2805

Overview

Damien D. Pearse is affiliated with the University of Miami in the United States and has a research focus spanning multiple fields within medicine and molecular biology. Their work primarily addresses neurological conditions, with particular attention to spinal cord injury and related neurodegenerative disorders.

The scientist's main fields of study include Medicine, Biochemistry, Genetics and Molecular Biology, and Neuroscience. Within these broader areas, Pearse's subfields of research explore Molecular Biology, Pathology and Forensic Medicine, Cellular and Molecular Neuroscience, Neurology, and Genetics.

Research topics covered by Pearse notably involve spinal cord injury research, extracellular vesicles in disease, nerve injury and regeneration, circular RNAs in diseases, neuroinflammation and neurodegeneration mechanisms, amyotrophic lateral sclerosis research, as well as neurogenetic and muscular disorders research.

Several recent publications illustrate Pearse's contributions to these topics:

  • "Phase 1 Safety Trial of Autologous Human Schwann Cell Transplantation in Chronic Spinal Cord Injury," 2021, Journal of Neurotrauma
  • "Schwann Cell-Derived Exosomal Vesicles: A Promising Therapy for the Injured Spinal Cord," 2023, International Journal of Molecular Sciences
  • "The Yin and Yang of Microglia-Derived Extracellular Vesicles in CNS Injury and Diseases," 2024, Cells
  • "Treating amyotrophic lateral sclerosis with allogeneic Schwann cell-derived exosomal vesicles: a case report," 2024, Neural Regeneration Research
  • "Sex Dependent Disparities in the Central Innate Immune Response after Moderate Spinal Cord Contusion in Rat," 2024, Cells

Pearse often collaborates with other researchers who are frequent co-authors, including Mousumi Ghosh, W. Dalton Dietrich, James D. Guest, Aisha Khan, and Allan D. Levi.

Publication venues where Pearse frequently publishes include:

  • International Journal of Molecular Sciences
  • Cells
  • Journal of Neurotrauma
  • Neural Regeneration Research
  • International Journal of Nanomedicine

Best Publications

  • cAMP and Schwann cells promote axonal growth and functional recovery after spinal cord injury

    Damien P. Pearse;Francisco Carlos Pereira;Alexander E. Marcillo;Margaret L. Bates

  • Combining Schwann Cell Bridges and Olfactory-Ensheathing Glia Grafts with Chondroitinase Promotes Locomotor Recovery after Complete Transection of the Spinal Cord

    Karim Fouad;Lisa Schnell;Lisa Schnell;Mary B. Bunge;Martin E. Schwab;Martin E. Schwab

  • Transplantation of Schwann cells and/or olfactory ensheathing glia into the contused spinal cord: Survival, migration, axon association, and functional recovery.

    Damien Daniel Pearse;Andre R. Sanchez;Francisco C. Pereira;Christian M. Andrade

  • Specific pathophysiological functions of JNK isoforms in the brain.

    Stephan Brecht;Rainer Kirchhof;Ansgar Chromik;Mette Willesen

  • Safety of Autologous Human Schwann Cell Transplantation in Subacute Thoracic Spinal Cord Injury.

    Kim D. Anderson;James D. Guest;W. Dalton Dietrich;Mary Bartlett Bunge

  • Cyclic AMP is a key regulator of M1 to M2a phenotypic conversion of microglia in the presence of Th2 cytokines.

    Mousumi Ghosh;Yong Xu;Damien D. Pearse

  • Combination of Engineered Schwann Cell Grafts to Secrete Neurotrophin and Chondroitinase Promotes Axonal Regeneration and Locomotion after Spinal Cord Injury

    Haruo Kanno;Yelena Pressman;Alison Moody;Randall Berg

  • Survival, integration, and axon growth support of glia transplanted into the chronically contused spinal cord.

    D. J. Barakat;S. M. Gaglani;S. R. Neravetla;A. R. Sanchez

  • Critical data-based re-evaluation of minocycline as a putative specific microglia inhibitor.

    Thomas Moller;Frederique Bard;Anindya Bhattacharya;Knut Biber

  • Histopathological and behavioral characterization of a novel cervical spinal cord displacement contusion injury in the rat.

    Damien Daniel Pearse;T. P. Lo;K. S. Cho;M. P. Lynch

  • Modulation of the cAMP signaling pathway after traumatic brain injury.

    Coleen M. Atkins;Anthony A. Oliva;Ofelia F. Alonso;Damien D. Pearse

  • Transplantation strategies to promote repair of the injured spinal cord.

    Mary Bartlett Bunge;Damien D. Pearse

  • Transplantation of Schwann cells and olfactory ensheathing glia after spinal cord injury: does pretreatment with methylprednisolone and interleukin-10 enhance recovery?

    Damien Daniel Pearse;Alexander Eduardo Marcillo;Martin Oudega;Michael Paul Lynch

  • Transduced Schwann cells promote axon growth and myelination after spinal cord injury.

    Kevin L. Golden;Damien D. Pearse;Bas Blits;Maneesh S. Garg

  • Schwann cell transplantation for spinal cord injury repair: its significant therapeutic potential and prospectus

    Haruo Kanno;Haruo Kanno;Damien D. Pearse;Hiroshi Ozawa;Eiji Itoi

  • Systemic hypothermia improves histological and functional outcome after cervical spinal cord contusion in rats.

    Thomas Pang Lo;Kyoung Suok Cho;Maneesh Sen Garg;Michael Patrick Lynch

  • Transgenic inhibition of astroglial NF-κB leads to increased axonal sparing and sprouting following spinal cord injury

    Roberta Brambilla;Andres Hurtado;Trikaldarshi Persaud;Kim Esham

  • The role of the serotonergic system in locomotor recovery after spinal cord injury.

    Mousumi Ghosh;Damien D. Pearse

  • Designing cell- and gene-based regeneration strategies to repair the injured spinal cord.

    Damien Daniel Pearse;M. B. Bunge

  • Up-regulation of glomerular COX-2 by angiotensin II: Role of reactive oxygen species

    Edgar A. Jaimes;Run Xia Tian;Damien Pearse;Leopoldo Raij

Frequent Co-Authors

Mary Bartlett Bunge
Mary Bartlett Bunge University of Miami
W. Dalton Dietrich
W. Dalton Dietrich University of Miami
Patrick M. Wood
Patrick M. Wood University of Miami
Karim Fouad
Karim Fouad University of Alberta
Lisa Schnell
Lisa Schnell University of Zurich
Martin E. Schwab
Martin E. Schwab University of Zurich
Lorne M. Mendell
Lorne M. Mendell Stony Brook University
Paul D. Dalton
Paul D. Dalton University of Oregon
Monica A. Perez
Monica A. Perez Shirley Ryan AbilityLab
Coleen M. Atkins
Coleen M. Atkins University of Miami

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