What is she best known for?
The fields of study she is best known for:
Paula M. Pitha spends much of her time researching Molecular biology, Interferon regulatory factors, Interferon, Gene and Transcription factor.
The study incorporates disciplines such as Promoter, Response element, Gene expression, Transactivation and Regulation of gene expression in addition to Molecular biology.
Her study in Interferon regulatory factors is interdisciplinary in nature, drawing from both Signal transduction, Cell biology, Transcription and IRF1.
In her research, Chloramphenicol acetyltransferase and DNA-binding protein is intimately related to Vero cell, which falls under the overarching field of Interferon.
Her work deals with themes such as Alpha interferon and Virology, which intersect with Gene.
Paula M. Pitha focuses mostly in the field of Transcription factor, narrowing it down to matters related to Chemokine and, in some cases, Ligand and MAPK/ERK pathway.
Her most cited work include:
- LPS-TLR4 Signaling to IRF-3/7 and NF-κB Involves the Toll Adapters TRAM and TRIF (977 citations)
- Virus-Dependent Phosphorylation of the IRF-3 Transcription Factor Regulates Nuclear Translocation, Transactivation Potential, and Proteasome-Mediated Degradation (772 citations)
- E-Cadherin Expression Is Silenced by DNA Hypermethylation in Human Breast and Prostate Carcinomas (745 citations)
What are the main themes of her work throughout her whole career to date?
Her primary areas of investigation include Interferon, Molecular biology, Virology, Gene and Interferon regulatory factors.
Her Interferon research includes elements of RNA, Fibroblast, Biochemistry and Cell biology.
Her Molecular biology research includes themes of Promoter, Gene expression, Transcription factor, Alpha interferon and Regulation of gene expression.
As part of one scientific family, Paula M. Pitha deals mainly with the area of Virology, narrowing it down to issues related to the Genetic enhancement, and often Viral etiology.
Her Gene research integrates issues from Cell culture and Herpes simplex virus.
Her research integrates issues of Response element, IRF1 and Transactivation in her study of Interferon regulatory factors.
She most often published in these fields:
- Interferon (44.70%)
- Molecular biology (43.78%)
- Virology (34.56%)
What were the highlights of her more recent work (between 2004-2014)?
- Immunology (14.29%)
- Interferon regulatory factors (19.82%)
- Virology (34.56%)
In recent papers she was focusing on the following fields of study:
The scientist’s investigation covers issues in Immunology, Interferon regulatory factors, Virology, Interferon and Transcription factor.
Her Immune system and Tumor necrosis factor alpha study in the realm of Immunology interacts with subjects such as Leishmania donovani.
Her Interferon regulatory factors research is multidisciplinary, incorporating elements of Cancer research, Antigen, Molecular biology, IRF1 and Primary effusion lymphoma.
Her Molecular biology research incorporates themes from Promoter, TLR3 and PRDM1.
Her work carried out in the field of Virology brings together such families of science as Innate immune system and Downregulation and upregulation.
Paula M. Pitha combines subjects such as Type I interferon production, TLR7, Gene and IRF3 with her study of Interferon.
Between 2004 and 2014, her most popular works were:
- The Interferon Regulatory Factor, IRF5, Is a Central Mediator of Toll-like Receptor 7 Signaling (328 citations)
- Innate antiviral response targets HIV-1 release by the induction of ubiquitin-like protein ISG15 (291 citations)
- The IRF family, revisited (220 citations)
In her most recent research, the most cited papers focused on:
Her scientific interests lie mostly in Interferon regulatory factors, Interferon, Ubiquitin, Molecular biology and ISG15.
Her biological study spans a wide range of topics, including Signal transduction and TLR3.
Her studies in Interferon integrate themes in fields like Cancer research, Transcription factor and Proteasome.
Her research ties Gene isoform and Molecular biology together.
The ISG15 study which covers Innate immune system that intersects with Virology, Mononegavirales, Filoviridae, RNA and RNA virus.
In her study, which falls under the umbrella issue of Gene, Virus is strongly linked to Cell culture.
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