Yasushi Fujio

Overview

Best Publications

• Regulation of endothelium-derived nitric oxide production by the protein kinase Akt.

  David Fulton;Jean Philippe Gratton;Timothy J. McCabe;Jason Fontana

  3126
  Citations

• Cardiomyocyte grafting for cardiac repair: graft cell death and anti-death strategies.

  Ming Zhang;Danielle Methot;Veronica Poppa;Yasushi Fujio

  1110
  Citations

• Akt Promotes Survival of Cardiomyocytes In Vitro and Protects Against Ischemia-Reperfusion Injury in Mouse Heart

  Yasushi Fujio;Thao Nguyen;Detlef Wencker;Richard N. Kitsis

  1005
  Citations

• Akt Mediates Cytoprotection of Endothelial Cells by Vascular Endothelial Growth Factor in an Anchorage-dependent Manner

  Yasushi Fujio;Kenneth Walsh

  722
  Citations

• Reactive Oxygen Species Mediate the Activation of Akt/Protein Kinase B by Angiotensin II in Vascular Smooth Muscle Cells

  Masuko Ushio-Fukai;R. Wayne Alexander;Marjorie Akers;Qi Qin Yin

  656
  Citations

• Vascular endothelial growth factor-stimulated actin reorganization and migration of endothelial cells is regulated via the serine/threonine kinase Akt

  Manuel Morales-Ruiz;David Fulton;Grzegorz Sowa;Lucia R. Languino

  514
  Citations

• Activation of gp130 Transduces Hypertrophic Signals via STAT3 in Cardiac Myocytes

  Keita Kunisada;Eiroh Tone;Yasushi Fujio;Hideo Matsui

  339
  Citations

• Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase.

  Shinji Negoro;Keita Kunisada;Yasushi Fujio;Masanobu Funamoto

  334
  Citations

• Cell cycle withdrawal promotes myogenic induction of Akt, a positive modulator of myocyte survival.

  Yasushi Fujio;Kun Guo;Kun Guo;Toshiaki Mano;Yasuhiro Mitsuuchi

  312
  Citations

• Erratum: Regulation of endothelium-derived nitric oxide production by the protein kinase Akt (Nature (1999) 399 (597-601))

  D. Fulton;J. P. Gratton;T. J. McCabe;J. Fontana

  308
  Citations

• Signals through gp130 upregulate bcl-x gene expression via STAT1-binding cis-element in cardiac myocytes.

  Yasushi Fujio;Keita Kunisada;Hisao Hirota;Keiko Yamauchi-Takihara

  299
  Citations

• Acute modulation of endothelial Akt/PKB activity alters nitric oxide–dependent vasomotor activity in vivo

  Zhengyu Luo;Yasushi Fujio;Yasuko Kureishi;Radu Daniel Rudic

  296
  Citations

• Pharmacokinetics/genotype associations for major cytochrome P450 enzymes in native and first- and third-generation Japanese populations: comparison with Korean, Chinese, and Caucasian populations.

  SP Myrand;K Sekiguchi;MZ Man;X Lin

  296
  Citations

• NAT2 genotype guided regimen reduces isoniazid-induced liver injury and early treatment failure in the 6-month four-drug standard treatment of tuberculosis: A randomized controlled trial for pharmacogenetics-based therapy

  Junichi Azuma;Masako Ohno;Masako Ohno;Ryuji Kubota;Soichiro Yokota

  282
  Citations

• Constitutive Activation of JAK3/STAT3 in Colon Carcinoma Tumors and Cell Lines: Inhibition of JAK3/STAT3 Signaling Induces Apoptosis and Cell Cycle Arrest of Colon Carcinoma Cells

  Quan Lin;Raymond Lai;Lucian R. Chirieac;Changping Li

  281
  Citations

• Glycoprotein 130 Regulates Cardiac Myocyte Survival in Doxorubicin-Induced Apoptosis Through Phosphatidylinositol 3-Kinase/Akt Phosphorylation and Bcl-xL/Caspase-3 Interaction

  Shinji Negoro;Hidemasa Oh;Eiroh Tone;Keita Kunisada

  277
  Citations

• Activation of JAK-STAT and MAP Kinases by Leukemia Inhibitory Factor Through gp130 in Cardiac Myocytes

  Keita Kunisada;Hisao Hirota;Yasushi Fujio;Hideo Matsui

  276
  Citations

• ACTIVATION OF PHOSPHATIDYLINOSITOL 3-KINASE THROUGH GLYCOPROTEIN 130 INDUCES PROTEIN KINASE B AND P70 S6 KINASE PHOSPHORYLATION IN CARDIAC MYOCYTES

  Hidemasa Oh;Yasushi Fujio;Keita Kunisada;Hisao Hirota

  272
  Citations

• Taurine depletion caused by knocking out the taurine transporter gene leads to cardiomyopathy with cardiac atrophy

  Takashi Ito;Yasushi Kimura;Yoriko Uozumi;Mika Takai

  270
  Citations

• Selective inhibition of STAT3 induces apoptosis and G(1) cell cycle arrest in ALK-positive anaplastic large cell lymphoma.

  Hesham M Amin;Timothy J McDonnell;Yupo Ma;Quan Lin

  238
  Citations