World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
14340
World Ranking
16491
National Ranking
465

Overview

Yanhui Xu is affiliated with Shanghai Medical College of Fudan University in China. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. Within these broad disciplines, their work is more specifically situated in subfields including Molecular Biology, Oncology, Infectious Diseases, Rheumatology, and Cell Biology.

The scientist's publications focus on several main research topics:

  • RNA Research and Splicing
  • RNA modifications and cancer
  • Genomics and Chromatin Dynamics
  • RNA and protein synthesis mechanisms
  • Rheumatoid Arthritis Research and Therapies
  • Epigenetics and DNA Methylation
  • Cancer-related gene regulation

Frequent collaborators of Yanhui Xu include Xizi Chen, Yulei Ren, Zishuo Yu, Xinxin Wang, and Weida Liu, reflecting a network of partnerships that support multidisciplinary inquiry.

The scientist has published extensively in several notable venues. The most frequent publication outlets include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Science
  • Nature Communications
  • Science Advances
  • Annals of the Rheumatic Diseases

Some recent significant papers contributing to their field include the following:

  • "Structure of nucleosome-bound human BAF complex," 2020, Science
  • "Potential therapeutic effects of dipyridamole in the severely ill patients with COVID-19," 2020, Acta Pharmaceutica Sinica B
  • "U1 snRNP regulates chromatin retention of noncoding RNAs," 2020, Nature
  • "Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase," 2020, Science
  • "Structural insights into preinitiation complex assembly on core promoters," 2021, Science

Best Publications

  • Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

    Wei Xu;Hui Yang;Ying Liu;Ying Yang

  • Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

    Mengtao Xiao;Hui Yang;Wei Xu;Shenghong Ma

  • Structure of the Protein Phosphatase 2A Holoenzyme.

    Yanhui Xu;Yongna Xing;Yu Chen;Yang Chao

  • Crystal Structure of TET2-DNA Complex: Insight into TET-Mediated 5mC Oxidation

    Lulu Hu;Ze Li;Jingdong Cheng;Qinhui Rao

  • Structure of Protein Phosphatase 2A Core Enzyme Bound to Tumor-Inducing Toxins

    Yongna Xing;Yanhui Xu;Yu Chen;Philip D. Jeffrey

  • Structural insights into the YAP and TEAD complex

    Ze Li;Bin Zhao;Ping Wang;Fei Chen

  • Structural insight into autoinhibition and histone H3-induced activation of DNMT3A

    Xue Guo;Ling Wang;Jie Li;Zhanyu Ding

  • Structure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau Dephosphorylation

    Yanhui Xu;Yu Chen;Ping Zhang;Philip D. Jeffrey

  • Lysine-5 acetylation negatively regulates lactate dehydrogenase a and is decreased in pancreatic cancer

    Di Zhao;Shao Wu Zou;Ying Liu;Xin Zhou

  • Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine

    Tingting Zhu;Ian A Roundtree;Ping Wang;Xiao Wang

  • Structural insight into substrate preference for TET-mediated oxidation

    Lulu Hu;Lulu Hu;Junyan Lu;Jingdong Cheng;Qinhui Rao

  • Crystal structure of severe acute respiratory syndrome coronavirus spike protein fusion core.

    Yanhui Xu;Zhiyong Lou;Yiwei Liu;Hai Pang

  • Structure of nucleosome-bound human BAF complex.

    Shuang He;Zihan Wu;Yuan Tian;Zishuo Yu

  • PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression.

    Eerappa Rajakumara;Zhentian Wang;Honghui Ma;Lulu Hu

  • U1 snRNP regulates chromatin retention of noncoding RNAs

    Yafei Yin;J. Yuyang Lu;Xuechun Zhang;Wen Shao

  • Structural Basis for Coronavirus-mediated Membrane Fusion CRYSTAL STRUCTURE OF MOUSE HEPATITIS VIRUS SPIKE PROTEIN FUSION CORE

    Yanhui Xu;Yiwei Liu;Zhiyong Lou;Lan Qin

  • Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.

    Hai Zheng;Yilun Qi;Shibin Hu;Xuan Cao

  • Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.

    Jingdong Cheng;Huirong Yang;Jian Fang;Lixiang Ma

  • Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors.

    Jieqing Zhu;Gengfu Xiao;Yanhui Xu;Fang Yuan

  • Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin-like, containing PHD and RING finger domains, 1) protein.

    Jingdong Cheng;Yi Yang;Jian Fang;Jianxiong Xiao

Frequent Co-Authors

Zihe Rao
Zihe Rao Tsinghua University
George F. Gao
George F. Gao Chinese Center For Disease Control and Prevention
Zhiyong Lou
Zhiyong Lou Tsinghua University
Yigong Shi
Yigong Shi Westlake University
Kun-Liang Guan
Kun-Liang Guan Westlake University
Yujiang Geno Shi
Yujiang Geno Shi Harvard University
Po Tien
Po Tien Chinese Academy of Sciences
Jiawei Wang
Jiawei Wang Tsinghua University
Philip D. Jeffrey
Philip D. Jeffrey Princeton University
Yu Chen
Yu Chen New York University

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