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Stephen F. Schaffner

Stephen F. Schaffner

D-Index & Metrics

Genetics

D-Index
71
Citations
110882
World Ranking
2139
National Ranking
970

Overview

Stephen F. Schaffner is affiliated with the Broad Institute in the United States. Their research primarily spans the field of Medicine, with a focus on Infectious Diseases, Public Health, Environmental and Occupational Health, Genetics, Molecular Biology, and Epidemiology.

The main research topics covered by Schaffner include:

  • Malaria Research and Control
  • Mosquito-borne diseases and control
  • SARS-CoV-2 and COVID-19 Research
  • Viral Infections and Outbreaks Research
  • Viral Infections and Vectors
  • SARS-CoV-2 detection and testing
  • Animal Virus Infections Studies

Schaffner has frequently published in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Malaria Journal
  • Cell
  • Science

Their recent notable papers include:

  • Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant, 2020, Cell
  • Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness, 2022, Science
  • Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events, 2020, Science
  • Deployable CRISPR-Cas13a diagnostic tools to detect and report Ebola and Lassa virus cases in real-time, 2020, Nature Communications
  • Single-Cell Profiling of Ebola Virus Disease In Vivo Reveals Viral and Host Dynamics, 2020, Cell

Schaffner has collaborated frequently with several co-authors including:

  • Pardis C. Sabeti
  • Bronwyn MacInnis
  • Katherine J. Siddle
  • Dyann F. Wirth
  • Daniel J. Park

Best Publications

  • A global reference for human genetic variation.

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

  • An integrated map of genetic variation from 1,092 human genomes

    Goncalo R Abecasis;Adam Auton;Lisa D Brooks

  • Table S2: Trans-factors and trinucleotide repeat instability Trans-factor

    Arturo López Castel;John D Cleary;Christopher E Pearson

  • The Structure of Haplotype Blocks in the Human Genome

    Stacey B. Gabriel;Stephen F. Schaffner;Huy Nguyen;Jamie M. Moore

  • The International HapMap Project

    John W. Belmont;Paul Hardenbol;Thomas D. Willis;Fuli Yu

  • A haplotype map of the human genome

    John W. Belmont;Andrew Boudreau;Suzanne M. Leal;Paul Hardenbol

  • A second generation human haplotype map of over 3.1 million SNPs

    Kelly A. Frazer;Dennis G. Ballinger;David R. Cox;David A. Hinds

  • Integrating common and rare genetic variation in diverse human populations

    D M Altshuler;R A Gibbs;L Peltonen

  • A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

    Ravi Sachidanandam;David Weissman;Steven C. Schmidt;Jerzy M. Kakol

  • Genome-wide detection and characterization of positive selection in human populations

    Pardis C. Sabeti;Pardis C. Sabeti;Patrick Varilly;Patrick Varilly;Ben Fry;Jason Lohmueller

  • The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes.

    David Altshuler;Joel N. Hirschhorn;Joel N. Hirschhorn;Joel N. Hirschhorn;Mia Klannemark;Cecilia M. Lindgren;Cecilia M. Lindgren

  • Initial sequence of the chimpanzee genome and comparison with the human genome

    Tarjei S. Mikkelsen;LaDeana W. Hillier

  • High-resolution haplotype structure in the human genome.

    Mark J. Daly;John D. Rioux;Stephen F. Schaffner;Thomas J. Hudson;Thomas J. Hudson

  • Detecting recent positive selection in the human genome from haplotype structure

    Pardis C Sabeti;David E Reich;John M Higgins;Haninah Z P Levine

  • Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak

    Stephen K. Gire;Stephen K. Gire;Augustine Goba;Kristian G. Andersen;Kristian G. Andersen;Rachel S G Sealfon;Rachel S G Sealfon

  • Positive Natural Selection in the Human Lineage

    P. C. Sabeti;S. F. Schaffner;B. Fry;J. Lohmueller

  • Mapping copy number variation by population-scale genome sequencing

    Ryan E. Mills;Klaudia Walter;Chip Stewart;Robert E. Handsaker

  • Genetic signatures of strong recent positive selection at the lactase gene.

    Todd Bersaglieri;Pardis C. Sabeti;Nick Patterson;Trisha Vanderploeg

  • Structural and Functional Analysis of the D614G SARS-CoV-2 Spike Protein Variant.

    Leonid Yurkovetskiy;Xue Wang;Kristen E. Pascal;Christopher Tomkins-Tinch

  • A global reference for human genetic variation

    Adam Auton;Gonçalo R. Abecasis;David M. Altshuler;Richard M. Durbin

Frequent Co-Authors

Pardis C. Sabeti
Pardis C. Sabeti Harvard University
Sarah K. Volkman
Sarah K. Volkman Harvard University
Dyann F. Wirth
Dyann F. Wirth Harvard University
Eric S. Lander
Eric S. Lander Broad Institute
Kristian G. Andersen
Kristian G. Andersen Scripps Research Institute
Daniel E. Neafsey
Daniel E. Neafsey Broad Institute
David Altshuler
David Altshuler Harvard University
Mark J. Daly
Mark J. Daly Massachusetts General Hospital
Bronwyn MacInnis
Bronwyn MacInnis Broad Institute
Robert F. Garry
Robert F. Garry Tulane University

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