D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 61 Citations 11,194 312 World Ranking 6116 National Ranking 144

Overview

What is she best known for?

The fields of study she is best known for:

  • Internal medicine
  • Chemotherapy
  • Cancer

Pharmacology, Pharmacokinetics, Chemotherapy, Oral administration and Paclitaxel are her primary areas of study. Her Pharmacology research includes elements of Camptothecin and Docetaxel. Her Pharmacokinetics study combines topics from a wide range of disciplines, such as Metabolite, Topotecan, Toxicity, Enzyme inhibitor and Drug.

Her research in Chemotherapy intersects with topics in Nausea, Regimen and Vomiting. The Oral administration study combines topics in areas such as Knockout mouse and Multidrug resistance-associated protein 2. Her studies deal with areas such as Oral therapy, Ovarian cancer, Co administration and Antibiotics as well as Paclitaxel.

Her most cited work include:

  • The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria (674 citations)
  • Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not? (391 citations)
  • Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918 (390 citations)

What are the main themes of her work throughout her whole career to date?

Her scientific interests lie mostly in Chromatography, Pharmacokinetics, Pharmacology, High-performance liquid chromatography and Tandem mass spectrometry. Her research in Chromatography tackles topics such as Metabolite which are related to areas like Tamoxifen. Her Pharmacokinetics study integrates concerns from other disciplines, such as Paclitaxel, Topotecan, Chemotherapy and Urine.

Her Paclitaxel research incorporates elements of Cyclosporin a and Urology. Her research integrates issues of Excretion and Toxicity in her study of Pharmacology. Her Tandem mass spectrometry research is multidisciplinary, relying on both Electrospray, Therapeutic drug monitoring and Electrospray ionization.

She most often published in these fields:

  • Chromatography (42.46%)
  • Pharmacokinetics (41.96%)
  • Pharmacology (37.19%)

What were the highlights of her more recent work (between 2017-2021)?

  • Pharmacokinetics (41.96%)
  • Internal medicine (15.33%)
  • Chromatography (42.46%)

In recent papers she was focusing on the following fields of study:

Hilde Rosing mostly deals with Pharmacokinetics, Internal medicine, Chromatography, Oncology and Pharmacology. She works on Pharmacokinetics which deals in particular with Therapeutic drug monitoring. Her Internal medicine research also works with subjects such as

  • DPYD which is related to area like Capecitabine, Dihydropyrimidine dehydrogenase and Prospective cohort study,
  • Gastroenterology and related Docetaxel, Chemotherapy and Oral Docetaxel.

Her Oncology research is multidisciplinary, incorporating elements of Clinical trial, Tamoxifen, Breast cancer, KRAS and Trametinib. Pharmacology and Receptor are commonly linked in her work. Her work carried out in the field of Bioanalysis brings together such families of science as Metabolite, Quantitative determination, Extraction and Mass spectrometry.

Between 2017 and 2021, her most popular works were:

  • DPYD genotype-guided dose individualisation of fluoropyrimidine therapy in patients with cancer: a prospective safety analysis. (95 citations)
  • Development and validation of a liquid chromatography-tandem mass spectrometry analytical method for the therapeutic drug monitoring of eight novel anticancer drugs. (29 citations)
  • A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy (24 citations)

In her most recent research, the most cited papers focused on:

  • Internal medicine
  • Cancer
  • Enzyme

Hilde Rosing spends much of her time researching Pharmacokinetics, Internal medicine, Oncology, Chromatography and Pharmacology. Her study in Pharmacokinetics is interdisciplinary in nature, drawing from both Cancer, Chemotherapy, Gemcitabine, MicroDose and Drug. She has researched Chemotherapy in several fields, including Gastroenterology and High-performance liquid chromatography.

Her study looks at the intersection of Internal medicine and topics like DPYD with Capecitabine. Her Chromatography research includes themes of Metabolite and Therapeutic drug monitoring. Her Pharmacology study incorporates themes from Dihydrouracil and Dihydropyrimidine dehydrogenase activity.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria

Johan W. Jonker;Marije Buitelaar;Els Wagenaar;Martin A. van der Valk.
Proceedings of the National Academy of Sciences of the United States of America (2002)

956 Citations

Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

Ellen Stokvis;Hilde Rosing;Jos H. Beijnen;Jos H. Beijnen.
Rapid Communications in Mass Spectrometry (2005)

672 Citations

Increased Oral Bioavailability of Topotecan in Combination With the Breast Cancer Resistance Protein and P-Glycoprotein Inhibitor GF120918

C. M.F. Kruijtzer;J. H. Beijnen;H. Rosing;W. W. ten Bokkel Huinink.
Journal of Clinical Oncology (2002)

600 Citations

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients

M.T. Huizing;A.C.F. Keung;H. Rosing;V. van der Kuij.
Journal of Clinical Oncology (1993)

437 Citations

Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel

Jetske M Meerum Terwogt;Wim W ten Bokkel Huinink;Jan Hm Schellens;Margaret Schot.
Anti-Cancer Drugs (2001)

373 Citations

Coadministration of Cyclosporine Strongly Enhances the Oral Bioavailability of Docetaxel

Mirte M. Malingré;Dick J. Richel;Jos H. Beijnen;Hilde Rosing.
Journal of Clinical Oncology (2001)

264 Citations

Multidrug Transporter ABCG2/Breast Cancer Resistance Protein Secretes Riboflavin (Vitamin B2) into Milk

Antonius E. van Herwaarden;Els Wagenaar;Gracia Merino;Johan W. Jonker.
Molecular and Cellular Biology (2007)

263 Citations

Coadministration of oral cyclosporin A enables oral therapy with paclitaxel.

Jetske M. Meerum Terwogt;Mirte M. Malingré;Jos H. Beijnen;Wim W. ten Bokkel Huinink.
Clinical Cancer Research (1999)

243 Citations

BIOANALYTICAL LIQUID CHROMATOGRAPHIC METHOD VALIDATION. A REVIEW OF CURRENT PRACTICES AND PROCEDURES

H. Rosing;W. Y. Man;E. Doyle;A. Bult.
Journal of Liquid Chromatography & Related Technologies (2000)

230 Citations

Phase I and Pharmacokinetic Study of Ecteinascidin-743, a New Marine Compound, Administered as a 24-hour Continuous Infusion in Patients With Solid Tumors

A. Taamma;J. L. Misset;M. Riofrio;C. Guzman.
Journal of Clinical Oncology (2001)

224 Citations

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