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Chemistry

D-Index
67
Citations
15473
World Ranking
6924
National Ranking
157

Overview

Hilde Rosing is affiliated with the Antoni van Leeuwenhoek Hospital in the Netherlands and has contributed extensively to medical research, with a specific emphasis on oncology and pharmacology. Their work encompasses multiple areas of medicine, especially oncology, molecular biology, pulmonary and respiratory medicine, pharmacology, and public health, environmental and occupational health.

The primary fields of study for Hilde Rosing include:

  • Medicine

Within these broad areas, their subfields of study are:

  • Oncology
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Pharmacology
  • Public Health, Environmental and Occupational Health

The main research topics covered by their publications are:

  • Pharmacogenetics and Drug Metabolism
  • Colorectal Cancer Treatments and Studies
  • Cancer Treatment and Pharmacology
  • Lung Cancer Treatments and Mutations
  • Research on Leishmaniasis Studies
  • Chronic Lymphocytic Leukemia Research
  • Cancer Genomics and Diagnostics

Hilde Rosing has collaborated frequently with several researchers including:

  • Jos H. Beijnen (84 coauthored works)
  • Alwin D. R. Huitema (55 coauthored works)
  • Neeltje Steeghs (17 coauthored works)
  • Jan H.M. Schellens (16 coauthored works)
  • Alfred H. Schinkel (14 coauthored works)

They have published across multiple journals, with notable frequency in:

  • Journal of Pharmaceutical and Biomedical Analysis (13 publications)
  • Journal of Chromatography B (9 publications)
  • Annals of Oncology (5 publications)
  • Cancer Chemotherapy and Pharmacology (5 publications)
  • Clinical Pharmacology & Therapeutics (4 publications)

Among their recent scientific contributions are the following papers:

  • "Therapeutic drug monitoring-based precision dosing of oral targeted therapies in oncology: a prospective multicenter study," 2022, Annals of Oncology
  • "Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study," 2022, Clinical Pharmacology & Therapeutics
  • "Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer," 2020, British Journal of Cancer
  • "Exposure-Response Analyses of Anaplastic Lymphoma Kinase Inhibitors Crizotinib and Alectinib in Non-Small Cell Lung Cancer Patients," 2020, Clinical Pharmacology & Therapeutics
  • "Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer," 2020, Cancer Chemotherapy and Pharmacology

Best Publications

  • Stable isotopically labeled internal standards in quantitative bioanalysis using liquid chromatography/mass spectrometry: necessity or not?

    Ellen Stokvis;Hilde Rosing;Jos H. Beijnen;Jos H. Beijnen

  • Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients

    M.T. Huizing;A.C.F. Keung;H. Rosing;V. van der Kuij

  • Phase I clinical and pharmacokinetic study of PNU166945, a novel water-soluble polymer-conjugated prodrug of paclitaxel

    Jetske M Meerum Terwogt;Wim W ten Bokkel Huinink;Jan Hm Schellens;Margaret Schot

  • Multidrug Transporter ABCG2/Breast Cancer Resistance Protein Secretes Riboflavin (Vitamin B2) into Milk

    Antonius E. van Herwaarden;Els Wagenaar;Gracia Merino;Johan W. Jonker

  • BIOANALYTICAL LIQUID CHROMATOGRAPHIC METHOD VALIDATION. A REVIEW OF CURRENT PRACTICES AND PROCEDURES

    H. Rosing;W. Y. Man;E. Doyle;A. Bult

  • Phase I and Pharmacokinetic Study of Ecteinascidin-743, a New Marine Compound, Administered as a 24-hour Continuous Infusion in Patients With Solid Tumors

    A. Taamma;J. L. Misset;M. Riofrio;C. Guzman

  • Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses.

    Ron J. Keizer;Ron J. Keizer;Robert S. Jansen;Hilde Rosing;Bas Thijssen

  • Phase I and pharmacological study of daily oral administration of perifosine (D-21266) in patients with advanced solid tumours

    M Crul;H Rosing;G.J de Klerk;R Dubbelman

  • Carcinogen and Anticancer Drug Transport by Mrp2 in Vivo: Studies Using Mrp2 (Abcc2) Knockout Mice

    M. L. H. Vlaming;K. Mohrmann;E. Wagenaar;D. R. de Waart

  • Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in N-glycosylation profile of the therapeutic monoclonal antibody trastuzumab

    Carola W. N. Damen;Weibin Chen;Asish B. Chakraborty;Mike van Oosterhout

  • The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry

    Elisabeth J Rook;Michel J X Hillebrand;Hilde Rosing;Jan M van Ree

  • A phase I and pharmacokinetic study of MAG-CPT, a water-soluble polymer conjugate of camptothecin.

    N E Schoemaker;C van Kesteren;H Rosing;S Jansen

  • High-performance liquid chromatographic procedures for the quantitative determination of paclitaxel (Taxol) in human urine.

    M.T. Huizing;H. Rosing;F. Koopman;A.C.F. Keung

  • Quantification of protease inhibitors and non-nucleoside reverse transcriptase inhibitors in dried blood spots by liquid chromatography-triple quadrupole mass spectrometry.

    R. ter Heine;H. Rosing;E.C.M. van Gorp;J.W. Mulder

  • Pharmacokinetics and pharmacodynamics of topotecan administered daily for 5 days every 3 weeks

    Laurence J. C. van Warmerdam;Jaap Verweij;Jan H. M. Schellens;Hilde Rosing

  • Method development and validation for the quantification of dasatinib, erlotinib, gefitinib, imatinib, lapatinib, nilotinib, sorafenib and sunitinib in human plasma by liquid chromatography coupled with tandem mass spectrometry.

    N. A. G. Lankheet;M. J. X. Hillebrand;H. Rosing;J. H. M. Schellens;J. H. M. Schellens

  • Phase I and Pharmacokinetic Study of Oral Paclitaxel

    Mirte M. Malingré;Jetske M. Meerum Terwogt;Jos H. Beijnen;Hilde Rosing

  • Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity.

    Didier Meulendijks;Linda M Henricks;Bart A W Jacobs;Abidin Aliev

  • A phase I and pharmacokinetic study of ecteinascidin-743 on a daily x 5 schedule in patients with solid malignancies.

    Miguel A Villalona-Calero;S Gail Eckhardt;Geoffrey Weiss;Manuel Hidalgo

  • Treatment of ovarian cancer using intraperitoneal chemotherapy with taxanes: from laboratory bench to bedside.

    Eelco de Bree;Panayiotis A. Theodoropoulos;Hilde Rosing;John Michalakis

  • Bioavailability andpharmacokinetics oforal topotecan: a new topoisomerase Iinhibitor

    JH Beijnen;H Rosing;M de Boer-Dennert;M McDonald

Frequent Co-Authors

Jos H. Beijnen
Jos H. Beijnen Utrecht University
Jan H.M. Schellens
Jan H.M. Schellens Utrecht University
Alfred H. Schinkel
Alfred H. Schinkel Antoni van Leeuwenhoek Hospital
Emile E. Voest
Emile E. Voest Antoni van Leeuwenhoek Hospital
René Bernards
René Bernards Antoni van Leeuwenhoek Hospital
Sjoerd Rodenhuis
Sjoerd Rodenhuis Antoni van Leeuwenhoek Hospital
H.M. Pinedo
H.M. Pinedo Vrije Universiteit Amsterdam
Hans Gelderblom
Hans Gelderblom Leiden University Medical Center
Henk-Jan Guchelaar
Henk-Jan Guchelaar Leiden University Medical Center
Ron H.J. Mathijssen
Ron H.J. Mathijssen Erasmus University Rotterdam

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