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D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
13353
World Ranking
11350
National Ranking
391

Overview

Lawrence D. Mayer is affiliated with the University of British Columbia in Canada. Their research spans multiple fields including Medicine and Materials Science, with a specific focus on subfields such as Hematology, Biomaterials, and Genetics.

The scientist's work primarily covers topics related to Acute Myeloid Leukemia Research, Nanoparticle-Based Drug Delivery, and Hemoglobinopathies and Related Disorders.

Among their recent publications is a paper titled Pharmacokinetics, drug metabolism, and tissue distribution of CPX-351 in animals, published in 2020 in the journal Nanomedicine Nanotechnology Biology and Medicine. This publication has garnered a notable number of citations.

Lawrence D. Mayer collaborates frequently with several coauthors, including:

  • Qi Wang
  • Paul Tardi
  • Nicole Sadowski
  • Sherwin Xie
  • Dennis Heller

Their published work appears primarily in the venue Nanomedicine Nanotechnology Biology and Medicine, which reflects a focus on interdisciplinary approaches blending medicine and materials science.

Best Publications

  • Vesicles of variable sizes produced by a rapid extrusion procedure

    L.D. Mayer;M.J. Hope;P.R. Cullis

  • Multidrug resistance (MDR) in cancer. Mechanisms, reversal using modulators of MDR and the role of MDR modulators in influencing the pharmacokinetics of anticancer drugs.

    Rajesh Krishna;Lawrence D Mayer

  • Liposomal compositions for enhanced retention of bioactive agents

    Marcel B. Bally;Nancy L. Boman;Pieter R. Cullis;Lawrence D. Mayer

  • Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles.

    L.D. Mayer;M.J. Hope;P.R. Cullis;A.S. Janoff

  • Generation of multilamellar and unilamellar phospholipid vesicles

    M.J. Hope;M.B. Bally;L.D. Mayer;A.S. Janoff

  • Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol).

    C. Allen;N. Dos Santos;N. Dos Santos;R. Gallagher;G.N.C. Chiu;G.N.C. Chiu

  • The liposomal formulation of doxorubicin.

    Sheela A Abraham;Dawn N Waterhouse;Lawrence D Mayer;Pieter R Cullis

  • Influence of Vesicle Size, Lipid Composition, and Drug-to-Lipid Ratio on the Biological Activity of Liposomal Doxorubicin in Mice

    Lawrence D. Mayer;Linda C. L. Tai;Dicken S. C. Ko;Dana Masin

  • Uptake of adriamycin into large unilamellar vesicles in response to a pH gradient.

    L.D. Mayer;M.B. Bally;P.R. Cullis

  • Reduced incidence of AD with NSAID but not H2 receptor antagonists: The Cache County Study

    Peter P. Zandi;James C. Anthony;Kathleen M. Hayden;Kala Mehta

  • Ratiometric dosing of anticancer drug combinations: Controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice

    Lawrence D. Mayer;Troy O. Harasym;Paul G. Tardi;Natashia L. Harasym

  • First-In-Man Study of CPX-351: A Liposomal Carrier Containing Cytarabine and Daunorubicin in a Fixed 5:1 Molar Ratio for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia

    Eric J. Feldman;Jeffrey E. Lancet;Jonathan E. Kolitz;Ellen K. Ritchie

  • Sphingosomes for enhanced drug delivery

    Murray S. Webb;Marcel B. Bally;Lawrence D. Mayer;James M. Miller

  • In vivo maintenance of synergistic cytarabine:daunorubicin ratios greatly enhances therapeutic efficacy

    Paul Tardi;Sharon Johnstone;Natashia Harasym;Sherwin Xie

  • Characterization of liposomal systems containing doxorubicin entrapped in response to pH gradients.

    Lawrence D. Mayer;Linda C.L. Tai;Marcel B. Bally;George N. Mitilenes

  • The accumulation of drugs within large unilamellar vesicles exhibiting a proton gradient: a survey.

    Thomas D. Madden;P.Richard Harrigan;Linda C.L. Tai;Marcel B. Bally

  • Antisense Oligonucleotides Targeting XIAP Induce Apoptosis and Enhance Chemotherapeutic Activity against Human Lung Cancer Cells in Vitro and in Vivo

    YanPing Hu;Gabriele Cherton-Horvat;Visia Dragowska;Stephen Baird

  • Sphingomyelin-cholesterol liposomes significantly enhance the pharmacokinetic and therapeutic properties of vincristine in murine and human tumour models.

    M. S. Webb;T. O. Harasym;D. Masin;M. B. Bally

  • Discovery and Characterization of OC144-093, a Novel Inhibitor of P-Glycoprotein-mediated Multidrug Resistance

    Michael J. Newman;Jennifer C. Rodarte;Khalid D. Benbatoul;Suzanne J. Romano

  • A comparison of liposomal formulations of doxorubicin with drug administered in free form: changing toxicity profiles.

    Dawn N. Waterhouse;Paul G. Tardi;Lawrence D. Mayer;Marcel B. Bally

Frequent Co-Authors

Marcel B. Bally
Marcel B. Bally University of British Columbia
Pieter R. Cullis
Pieter R. Cullis University of British Columbia
Michael J. Hope
Michael J. Hope University of British Columbia
Andrew S. Janoff
Andrew S. Janoff Princeton University
Karen A. Gelmon
Karen A. Gelmon University of British Columbia
Katarina Edwards
Katarina Edwards Uppsala University
Kim N. Chi
Kim N. Chi BC Cancer Agency
Walid Saad
Walid Saad Virginia Tech
John C.S. Breitner
John C.S. Breitner Douglas Mental Health University Institute
Robert K. Prud'homme
Robert K. Prud'homme Princeton University

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