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D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
10853
World Ranking
15056
National Ranking
531

Overview

Jody J. Haigh is affiliated with the University of Manitoba in Canada and has contributed extensively to the fields of medicine and biochemistry, genetics, and molecular biology. Their research emphasizes molecular biology, hematology, oncology, public health, environmental and occupational health, and surgery. The scientist's work spans multiple critical topics including acute lymphoblastic leukemia research, pluripotent stem cells research, cancer cells and metastasis, acute myeloid leukemia research, CRISPR and genetic engineering, congenital heart defects research, and genomics and chromatin dynamics.

Haigh has published numerous articles in prominent journals such as bioRxiv (Cold Spring Harbor Laboratory), Nature Communications, Cardiovascular Research, Blood, and Nature Cancer. These venues reflect a focus on cardiovascular, cancer, and hematological research disciplines.

The following recent papers highlight areas of investigation and their publication years and venues:

  • Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice, 2021, Science
  • Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner, 2021, Nature Communications
  • The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype, 2020, Cancer Research
  • Interplay between the EMT transcription factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity, 2021, PLoS Biology
  • Peripheral-specific Y1 receptor antagonism increases thermogenesis and protects against diet-induced obesity, 2021, Nature Communications

Frequent coauthors include:

  • Steven Goossens
  • Katharina Haigh
  • Carlos Farkas
  • Geert Berx
  • Stephen M. Jane

Haigh's research environments and collaboration networks likely engage with cardiovascular, cancer, and hematological topics, as suggested by coauthors and publication venues.

The scientist's work on topics related to acute lymphoblastic leukemia and acute myeloid leukemia research shows a strong focus on hematological cancers. Their research on CRISPR and genetic engineering indicates involvement with cutting-edge genetic editing technologies. Additional focus areas such as congenital heart defects research and genomics and chromatin dynamics demonstrate a multidisciplinary approach linking developmental biology, cardiology, and genome regulation.

Best Publications

  • Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases

    Vera Eremina;Manish Sood;Jody Haigh;András Nagy

  • A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

    Benjamin Beck;Gregory Driessens;Steven Goossens;Khalil Kass Youssef

  • Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction

    Gusztav Belteki;Jody Haigh;Jody Haigh;Nikolett Kabacs;Katharina Haigh;Katharina Haigh

  • MDM4 is a key therapeutic target in cutaneous melanoma

    Agnieszka Gembarska;Agnieszka Gembarska;Flavie Luciani;Flavie Luciani;Clare Fedele;Clare Fedele;Elisabeth A Russell

  • Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling.

    Jody J Haigh;Paula I Morelli;Holger Gerhardt;Katharina Haigh

  • Vascular Endothelial Growth Factor A Signaling in the Podocyte-Endothelial Compartment Is Required for Mesangial Cell Migration and Survival

    Vera Eremina;Shiying Cui;Hanspeter Gerber;Napoleone Ferrara

  • Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state

    Jody J. Haigh;Hans-Peter Gerber;Napoleone Ferrara;Erwin F. Wagner

  • Developmental and adult phenotyping directly from mutant embryonic stem cells.

    Sophia H. L. George;Marina Gertsenstein;Kristina Vintersten;Ella Korets-Smith

  • Transcriptional repressor ZEB2 promotes terminal differentiation of CD8+ effector and memory T cell populations during infection.

    Kyla D. Omilusik;J. Adam Best;Bingfei Yu;Steven Goossens;Steven Goossens

  • Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression.

    G Denecker;N Vandamme;Ö Akay;D Koludrovic

  • Increased skeletal VEGF enhances β‐catenin activity and results in excessively ossified bones

    Christa Maes;Steven Goossens;Sonia Bartunkova;Benjamin Drogat

  • Reversible reprogramming of cardiomyocytes to a fetal state drives heart regeneration in mice

    Yanpu Chen;Felipe F Lüttmann;Eric Schoger;Hans R Schöler

  • Direct Evidence for Endothelial Vascular Endothelial Growth Factor Receptor-1 Function in Nitric Oxide–Mediated Angiogenesis

    Shakil Ahmad;Peter W. Hewett;Ping Wang;Bahjat Al-Ani

  • VEGF Mediates Commissural Axon Chemoattraction through Its Receptor Flk1

    Carmen Ruiz de Almodovar;Pierre J. Fabre;Ellen Knevels;Cathy Coulon

  • Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

    Mary J. van Helden;Steven Goossens;Cécile Daussy;Anne-Laure Mathieu

  • Loss of vascular endothelial growth factor a activity in murine epidermal keratinocytes delays wound healing and inhibits tumor formation

    Heidemarie Rossiter;Caterina Barresi;Johannes Pammer;Michael Rendl

  • VEGFR2 (KDR/Flk1) Signaling Mediates Axon Growth in Response to Semaphorin 3E in the Developing Brain

    Anaïs Bellon;Jonathan Luchino;Katharina Haigh;Geneviève Rougon

  • The transcription factor Zeb2 regulates development of conventional and plasmacytoid DCs by repressing Id2

    Charlotte L. Scott;Charlotte L. Scott;Bieke Soen;Bieke Soen;Liesbet Martens;Liesbet Martens;Nicolas Skrypek;Nicolas Skrypek

  • Vascular Endothelial Growth Factor Directly Inhibits Primitive Neural Stem Cell Survival But Promotes Definitive Neural Stem Cell Survival

    Tamaki Wada;Jody J Haigh;Masatsugu Ema;Seiji Hitoshi

  • Role of VEGF in organogenesis.

    Jody J. Haigh

Frequent Co-Authors

Geert Berx
Geert Berx Ghent University
Andras Nagy
Andras Nagy Lunenfeld-Tanenbaum Research Institute
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Jose M. Polo
Jose M. Polo Monash University
Erwin F. Wagner
Erwin F. Wagner Medical University of Vienna
Peter A. Greer
Peter A. Greer Queen's University
Napoleone Ferrara
Napoleone Ferrara University of California, San Diego

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